Probiotic Microorganisms in Inflammatory Bowel Diseases: Live Biotherapeutics as Food DOI Creative Commons

Emanuelle Natalee dos Santos,

Karina Teixeira Magalhães‐Guedes, Fernando Elias de Melo Borges

et al.

Foods, Journal Year: 2024, Volume and Issue: 13(24), P. 4097 - 4097

Published: Dec. 18, 2024

(1) Background: Inflammatory bowel diseases (IBDs) are characterized by chronic and complex inflammatory processes of the digestive tract that evolve with frequent relapses manifest at any age; they predominantly affect young individuals. Diet plays a direct role in maintaining gut mucosal integrity immune function. Regarding diet, administration probiotics stands out. The use for IBD treatment has shown promising effects on consumers’ quality life. (2) Methods: This study aimed to conduct literature review probiotic smart ingestion analyze available based searched keywords using boxplot diagrams search scientific data online published up October 2024. (3) Results: Google Scholar (containing ~6 × 106 articles) Science Direct ~5 were databases highest number articles used study. When analyzing content articles, although microorganisms currently not part standard protocol IBD, these live biotherapeutics have proven be an effective option, considering adverse conventional therapies. Furthermore, development genetically engineered or is IBD. (4) Conclusions: Probiotics could represent future nutritional medicine care, allowing patients treated more natural, safe, effective, nutritious way. However, many studies demonstrated potential this biotherapy, clinical trials standardizing dosage strains still necessary.

Language: Английский

Beyond hormones: 3PM approach to vaginal microbiota dynamics in postmenopausal women DOI

Panchita Pongsupasamit,

Chanisa Thonusin, Suchaya Luewan

et al.

The EPMA Journal, Journal Year: 2025, Volume and Issue: unknown

Published: April 15, 2025

Language: Английский

Citations

0
Very-Low-Absorbable Geraniol for the Treatment of Irritable Bowel Syndrome: A “Real-World” Open-Label Study on 1585 Patients DOI Open Access
Chiara Ricci, Ilaria Maria Saracino, Maria Chiara Valerii

et al.

Nutrients, Journal Year: 2025, Volume and Issue: 17(2), P. 328 - 328

Published: Jan. 17, 2025

The objective of this study was to evaluate the efficacy a very-low-absorbable geraniol formulation, administered as food supplement, in patients with irritable bowel syndrome (IBS) real-world setting Italy. This open-label conducted Italy on diagnosed IBS and treated for 4 weeks 240 mg/day Palmarosa essential oil, absorbed 960 mg ginger root powder obtain formulation. Baseline characteristics, including demographic symptoms were recorded using Severity Scoring System (IBS-SSS). After 28 ± 7 days, asked complete IBS-SSS questionnaire again. primary confirm effects formulation self-reported quality life affected individuals. secondary effect treatment different subtypes. A total 1585 included study, mean age 44.8 years 56.4% women. Following 4-week supplementation period, significant decreases observed patients' (-67.9%) all symptoms, such abdominal distention (-82.3%), unsatisfaction habits (-46.2%), interference (QoL) (-64.9%) (all p < 0.01). stool type improved significantly. Treatment effective very-low-adsorbable supplement associated improvements subtypes These findings support use an option regardless disease subtype.

Language: Английский

Citations

0
Periodic Changes in the Gut Microbiome in Women with the Mixed Type of Irritable Bowel Syndrome DOI Creative Commons
Aleksandra Kaczka, Aleksandra Błońska, Cezary Chojnacki

et al.

Biomedicines, Journal Year: 2025, Volume and Issue: 13(3), P. 652 - 652

Published: March 7, 2025

Background: The mixed type of irritable bowel syndrome (IBS-M) is characterized by recurrent constipation and diarrhea. cause the variability these symptoms not sufficiently understood. aim this study was to perform metagenomic metabolic assessment gut microbiome in diarrheal period IBS-M. Methods: This included 30 women, aged 28–47 years old, with which aligned those IBS-M, according Rome IV Criteria. Results: In both periods disease, dysbiosis index (DI), Shannon diversity (SDI), hydrogen–methane ammonia breath tests, as well selected bacterial metabolites (-p-hydroxyphenyl acetic acid (HPA), 3-indoxyl sulfate (Indican, 3-IS)), hippuric (A) urine, were determined. (DI) 3.73 ± 0.90 points, it did change significantly 3.93 0.75 points (p > 0.05). During period, bacteria increases from 2.16 0.59 2.74 0.50 on dietary < 0.001). profile also changed, especially during where an abundance Bifidobacterium spp. Lactobacillus decreased significantly. addition, levels hydrogen air increased, while methane level decreased. differences concern results urinary metabolites, related indican. ions Conclusions: patients periodic changes metabolism occur, coexist such

Language: Английский

Citations

0
Probiotic Microorganisms in Inflammatory Bowel Diseases: Live Biotherapeutics as Food DOI Creative Commons

Emanuelle Natalee dos Santos,

Karina Teixeira Magalhães‐Guedes, Fernando Elias de Melo Borges

et al.

Foods, Journal Year: 2024, Volume and Issue: 13(24), P. 4097 - 4097

Published: Dec. 18, 2024

(1) Background: Inflammatory bowel diseases (IBDs) are characterized by chronic and complex inflammatory processes of the digestive tract that evolve with frequent relapses manifest at any age; they predominantly affect young individuals. Diet plays a direct role in maintaining gut mucosal integrity immune function. Regarding diet, administration probiotics stands out. The use for IBD treatment has shown promising effects on consumers’ quality life. (2) Methods: This study aimed to conduct literature review probiotic smart ingestion analyze available based searched keywords using boxplot diagrams search scientific data online published up October 2024. (3) Results: Google Scholar (containing ~6 × 106 articles) Science Direct ~5 were databases highest number articles used study. When analyzing content articles, although microorganisms currently not part standard protocol IBD, these live biotherapeutics have proven be an effective option, considering adverse conventional therapies. Furthermore, development genetically engineered or is IBD. (4) Conclusions: Probiotics could represent future nutritional medicine care, allowing patients treated more natural, safe, effective, nutritious way. However, many studies demonstrated potential this biotherapy, clinical trials standardizing dosage strains still necessary.

Language: Английский

Citations

0