Changes in Hormonal Profile and Body Mass Index in Women with Polycystic Ovary Syndrome After Probiotic Intake: A 12-Week Placebo-Controlled and Randomized Clinical Study

Nutrients, Journal Year: 2025, Volume and Issue: 17(3), P. 405 - 405

Published: Jan. 23, 2025

Introduction: The beneficial effect of probiotics on the improvement carbohydrate and lipid metabolism, as well body mass index (BMI), has been demonstrated in various patient groups. We aimed to investigate a multi-strain probiotic hormonal balance women with PCOS. Ethical approval was obtained from Bioethical Committee. Methods: study designed 12-week, randomized, double-blind, placebo-controlled clinical study. SanProbi® Barrier capsules, which contain unique composition nine bacteria strains (Lactobacillus Biffidobacterium), were used mean age participants 28.42 ± 5.62 years. A total 50 PCOS, diagnosed based Rotterdam ESHRE criteria, included Among them, 25 randomized placebo group, group. Results: comparison changes individual hormone levels between groups confirmed statistically significant differences for TSH, androstenedione, SHBG, BMI. In case LH, statistical significance difference delta change group use one-tailed test. Conclusions: Probiotic supplementation may serve an alternative supporting treatment, especially phenotype high FAI index. therapy is also effective reducing BMI overweight PCOS

Language: Английский

Impact of Probiotic Treatment on Clinical Symptom Reduction in Schizophrenia: A Systematic Review and Meta-Analysis

Journal of Psychiatric Research, Journal Year: 2025, Volume and Issue: 182, P. 413 - 420

Published: Jan. 24, 2025

Language: Английский