Carbohydrate Polymers, Journal Year: 2025, Volume and Issue: 356, P. 123381 - 123381
Published: Feb. 14, 2025
Language: Английский
Citations
2Journal of Advanced Research, Journal Year: 2025, Volume and Issue: unknown
Published: March 1, 2025
The impact of non-antibiotic feed additives on livestock performance and health is contingent upon a multitude variables, including the animal species, dosage type additives, duration oral administration. However, there paucity knowledge regarding relationship between these factors animals. objective this study was to conduct global meta-analysis based pool empirical studies investigate effects dietary growth, production, blood metabolites, immunity, intestinal morphology, abundance gut microbiota in livestock. A meta-regression coupled with dose-effect analysis performed ascertain optimal feeding for body function. total 71 papers, estimating 1, 035 effect size across 9 species 7 types were recruited our meta-dataset. Overall assessment confirmed that diet can significantly improve production immune function species. Our findings indicated more pronounced herbivores than omnivores. dose-response results overall doses antimicrobial peptides, enzymes, oligosaccharides, organic acids, phytogenic, probiotics prebiotics 100 mg/kg, 30 200 50 10⁶ CFU/kg, 10 respectively. Oral administration 2-month period effectively improves health. This evidence-based approach provides foundation implementing customized strategies designed optimize performance, enhance immunity reduce costs. shows are promising alternatives antibiotics reducing use antibiotics. Furthermore, suggest lead recommendations practical strategies, providing producers sustainable cost-effective management.
Language: Английский
Citations
0Food Hydrocolloids, Journal Year: 2025, Volume and Issue: unknown, P. 111350 - 111350
Published: March 1, 2025
Language: Английский
Citations
0Archives of Gerontology and Geriatrics Plus, Journal Year: 2025, Volume and Issue: unknown, P. 100142 - 100142
Published: March 1, 2025
Language: Английский
Citations
0International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 142678 - 142678
Published: March 1, 2025
Language: Английский
Citations
0Foods, Journal Year: 2025, Volume and Issue: 14(9), P. 1559 - 1559
Published: April 29, 2025
Neurodegenerative disorders such as Alzheimer’s disease (AD), the most common form of dementia, represent a growing global health crisis, yet current treatment strategies remain primarily palliative. Recent studies have shown that neurodegeneration through complex interactions within gut–brain axis largely depends on gut microbiota and its metabolites. This review explores intricate molecular mechanisms linking dysbiosis to cognitive decline, emphasizing impact microbial metabolites, including short-chain fatty acids (SCFAs), bile acids, tryptophan neuroinflammation, blood–brain barrier (BBB) integrity, amyloid-β tau pathology. The paper highlights major microbiome signatures associated with disease, detailing their metabolic pathways inflammatory crosstalk. Dietary interventions promise in modulating composition, potentially mitigating neurodegenerative processes. critically examines influence dietary patterns, Mediterranean Western diets, microbiota-mediated neuroprotection. Bioactive compounds like prebiotics, omega-3 polyphenols exhibit neuroprotective effects by reducing neuroinflammation. Furthermore, it discusses emerging microbiome-based therapeutic strategies, probiotics, postbiotics, fecal transplantation (FMT), potential for slowing progression. Despite these advances, several knowledge gaps remain, interindividual variability responses need large-scale, longitudinal studies. study proposes an integrative, precision medicine approach, incorporating science into paradigms. Ultimately, cognizance at mechanistic level could unlock novel avenues, offering non-invasive, diet-based strategy managing improving health.
Language: Английский
Citations
0Published: Jan. 1, 2024
Language: Английский
Citations
0