The incorporation of red meat in higher-HEI diets supports brain-health critical nutritional adequacy, and gut microbial diversity DOI Creative Commons
Samitinjaya Dhakal, Mosharraf Hossain, Sudip Parajuli

et al.

Research Square (Research Square), Journal Year: 2025, Volume and Issue: unknown

Published: March 24, 2025

Abstract We evaluated whether red meat could be integrated into a high Healthy Eating Index (HEI) diet to improve brain health-critical nutrient adequacy without compromising quality, mental health, or gut microbiota. Using data from 3,643 adults in the American Gut Project, participants were stratified four groups: high-HEI (≥ 80) with (HH-R), (HH-NR), low-HEI (< (LH-R), and (LH-NR). Both groups maintained healthy BMI values regardless of intake. HH-R had higher protein intake lower carbohydrate intake, saturated fat levels within recommended limits. Brain micronutrient adequacies (selenium, vitamin B12, zinc, calcium, D3, choline) significantly (p < 0.001). Higher HEI scores, irrespective consumption, associated reduced odds depression (logOR= -2.22), PTSD -3.80), bipolar disorder -5.90). microbiota diversity richness highest HH-R, increased Bacteroides caccae (padj = 0.003) Clostridium hathewayi 0.001), while HH-NR showed Bifidobacterium adolescentis eggerthii Therefore, these findings suggest that inclusion lean improves health-supporting adverse effects on health microbial diversity.

Language: Английский

The incorporation of red meat in higher-HEI diets supports brain-health critical nutritional adequacy, and gut microbial diversity DOI Creative Commons
Samitinjaya Dhakal, Mosharraf Hossain, Sudip Parajuli

et al.

Research Square (Research Square), Journal Year: 2025, Volume and Issue: unknown

Published: March 24, 2025

Abstract We evaluated whether red meat could be integrated into a high Healthy Eating Index (HEI) diet to improve brain health-critical nutrient adequacy without compromising quality, mental health, or gut microbiota. Using data from 3,643 adults in the American Gut Project, participants were stratified four groups: high-HEI (≥ 80) with (HH-R), (HH-NR), low-HEI (< (LH-R), and (LH-NR). Both groups maintained healthy BMI values regardless of intake. HH-R had higher protein intake lower carbohydrate intake, saturated fat levels within recommended limits. Brain micronutrient adequacies (selenium, vitamin B12, zinc, calcium, D3, choline) significantly (p < 0.001). Higher HEI scores, irrespective consumption, associated reduced odds depression (logOR= -2.22), PTSD -3.80), bipolar disorder -5.90). microbiota diversity richness highest HH-R, increased Bacteroides caccae (padj = 0.003) Clostridium hathewayi 0.001), while HH-NR showed Bifidobacterium adolescentis eggerthii Therefore, these findings suggest that inclusion lean improves health-supporting adverse effects on health microbial diversity.

Language: Английский

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