Health Effects and Therapeutic Potential of the Gut Microbe Akkermansia muciniphila

Nutrients, Journal Year: 2025, Volume and Issue: 17(3), P. 562 - 562

Published: Jan. 31, 2025

Akkermansia muciniphila is a bacterium commonly found in the human gastrointestinal tract that has received considerable interest as potential probiotic for improvement of gut health and overall metabolic function. A. enriched mucus layer intestinal lining, where it degrades mucin plays significant role barrier maintenance immune regulation. A higher abundance been observed healthy individuals relative to those with disorders, multiple benefits, including improved glucose management, reduced body fat, inflammation have linked muciniphila. Current research on primarily relies mouse models, limited interventional studies available. While these animal offer valuable insights into roles disease, further clinical investigations humans are needed fully understand its impact. Here, we explore current scope therapeutic agent improve while also emphasizing need optimize techniques this organism.

Language: Английский

Pasteurized Akkermansia muciniphila ameliorates preeclampsia via inhibiting mitochondrial dysfunction-mediated placental apoptosis in vivo and in vitro

Free Radical Biology and Medicine, Journal Year: 2025, Volume and Issue: 234, P. 233 - 247

Published: April 26, 2025

Language: Английский