Role of Serum and Dietary Vitamins A and E in Pulmonary Function and Chronic Obstructive Pulmonary Disease: A Systematic Review
Shabina Saifullah,
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Amna Ihsan,
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Syed Wajahat Ali Shah
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et al.
Pakistan Journal of Health Sciences,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 28, 2025
Chronic
Obstructive
Pulmonary
Disease
(COPD)
is
a
major
global
health
concern,
significantly
affecting
quality
of
life
and
healthcare
systems.
Oxidative
stress
plays
critical
role
in
COPD
pathogenesis.
Vitamins
A
E,
as
fat-soluble
antioxidants,
are
believed
to
support
pulmonary
health,
but
studies
report
conflicting
findings.
Objectives:
To
evaluate
associations
between
serum
dietary
concentrations
vitamins
E
with
function
parameters
risk
or
severity,
this
systematic
review
was
conducted.
Methods:
search
conducted
PubMed,
EMBASE,
Scopus,
the
Cochrane
Library.
Of
150
screened
studies,
22
met
inclusion
criteria,
comprising
cross-sectional,
cohort,
case-control,
interventional
designs.
Studies
assessing
levels
their
relationships
(FEV₁,
FVC,
FEV₁/FVC)
were
included.
Results:
Higher
vitamin
linked
improved
FEV₁
FVC
reduced
prevalence.
Vitamin
intake
associated
lower
COPD,
though
its
effects
on
lung
varied.
Supplementation
showed
mixed
results,
benefits
observed
mainly
when
combined
other
antioxidants.
Effects
more
pronounced
smokers
individuals
systemic
inflammation.
Conclusions:
particularly
A,
may
slow
progression.
However,
inconsistencies
highlighted
need
for
well-designed
trials
confirm
management.
Language: Английский
Nutritional Support of Chronic Obstructive Pulmonary Disease
Péter Simon,
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É Török,
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Klára Szalontai
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et al.
Nutrients,
Journal Year:
2025,
Volume and Issue:
17(7), P. 1149 - 1149
Published: March 26, 2025
Background:
COPD
is
a
heterogenous
disease
of
the
respiratory
tract
caused
by
diverse
genetic
factors
along
with
environmental
and
lifestyle-related
effects
such
as
industrial
dust
inhalation
and,
most
frequently,
cigarette
smoking.
These
lead
to
airflow
obstruction
chronic
symptoms.
Additionally,
increased
risk
infections
exacerbates
airway
inflammation
in
patients.
As
consequence
complex
pathomechanisms
difficulty
treatment,
among
leading
causes
mortality
both
western
countries
developing
world.
Results:
The
management
still
challenge
for
clinicians;
however,
alternative
interventions
smoking
cessation
lifestyle
changes
from
sedentary
life
moderate
physical
activity
special
attention
diet
may
ameliorate
patients'
health.
Here,
we
reviewed
different
dietary
components
supplements
on
conditions
COPD.
Conclusions:
patients
are
continuously
exposed
heavy
metals,
which
commonly
present
smoke
polluted
air.
Meanwhile,
they
often
experience
significant
nutrient
deficiencies,
affect
detoxification
these
toxic
metals.
This
turn
can
further
disrupt
nutritional
balance
interfering
absorption,
metabolism,
utilization
essential
micronutrients.
Therefore,
awareness
deliberate
efforts
should
be
made
check
levels
micronutrients,
ensuring
adequate
antioxidants,
vitamin
D,
K2,
magnesium,
iron,
particularly
important
reducing
development
limiting
severity.
Language: Английский
An Overview of Sarcopenia: Focusing on Nutritional Treatment Approaches
M. Barone,
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Palmina Baccaro,
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Alessio Molfino
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et al.
Nutrients,
Journal Year:
2025,
Volume and Issue:
17(7), P. 1237 - 1237
Published: April 1, 2025
Sarcopenia
is
a
syndrome
characterized
by
the
progressive
and
generalized
loss
of
skeletal
muscle
mass
strength.
This
condition
associated
with
physical
disability,
decreased
quality
life,
increased
mortality.
Therefore,
reducing
prevalence
sarcopenia
could
significantly
lower
healthcare
costs.
can
be
classified
into
primary
secondary
sarcopenia.
The
former
related
to
aging
begins
after
fourth
decade
life;
that,
there
around
8%
per
until
age
70
years,
which
subsequently
increases
15%
decade.
On
other
hand,
affect
all
individuals
may
result
from
various
factors
including
inactivity,
malnutrition,
endocrine
disorders,
neurodegenerative
diseases,
inflammation,
cachexia.
Understanding
multiple
mechanisms
involved
in
onset
progression
allows
for
us
develop
strategies
that
prevent,
treat,
or
at
least
mitigate
caused
protein
breakdown.
One
potential
treatment
based
on
nutritional
interventions,
adequate
caloric
intake
specific
nutrients
support
health.
Such
include
natural
food
rich
whey
omega-3
fatty
acids
as
well
supplements
like
branched-chain
amino
acids,
β-hydroxy-β-methylbutyrate,
vitamin
D
along
special
medical
purposes.
It
important
emphasize
exercises,
especially
resistance
training,
not
only
promote
synthesis
their
own
but
also
work
synergistically
enhance
effectiveness.
Language: Английский