The Role of Nutrition in Menstrual Cycle Regularity and the Management of Menstrual Disorder: A Review DOI

Harshita Gupta

Published: May 14, 2025

The menstrual cycle serves as a critical marker of women’s reproductive health and is intricately governed by hormonal interactions that are notably sensitive to external influences like diet. Recent studies emphasize the significant influence nutrition has on sustaining regularity mitigating disorders. A nutritionally balanced diet supports equilibrium, whereas poor eating habits frequently associated with disruptions. Conditions such polycystic ovary syndrome (PCOS), dysmenorrhea, premenstrual (PMS), functional hypothalamic amenorrhea have been linked inadequate dietary patterns. Diets high in refined sugars, Tran’s fats, processed items contribute insulin resistance fluctuations seen PCOS. In contrast, anti-inflammatory diets demonstrated benefits managing dysmenorrhea PMS symptoms, highlighting potential changes non-pharmacological strategy. Essential nutrients iron, magnesium, calcium, vitamin D, omega-3 fatty acids closely health. Iron replenishes blood loss, both magnesium B6 shown relieve symptoms. Vitamin D insufficiency correlates irregular menstruation PCOS risk. Mediterranean pattern, which fruits, vegetables, whole grains, healthy support balance, while high-glycemic severe calorie restriction may disrupt cycles trigger amenorrhea. This review emphasizes integral role plays regulation disorder management. Recognizing these connections can guide nutritional interventions enhance well-being holistic accessible manner. Further research essential create tailored guidelines for improving

Language: Английский

Association of Polycystic Ovary Syndrome with Clinical, Physical, and Reproductive Factors: A Data-Driven Analysis DOI Creative Commons

Ismat Ara Begum,

A. S. M. Sanwar Hosen, Deepak Ghimire

et al.

Diagnostics, Journal Year: 2025, Volume and Issue: 15(6), P. 711 - 711

Published: March 12, 2025

Background/Objectives: Polycystic Ovary Syndrome (PCOS) is a multifactorial endocrine disorder with significant clinical and reproductive implications. Identifying dose–response relationships between clinical, physical, factors PCOS can enhance diagnostic accuracy inform treatment strategies. This study utilized data-driven approach to analyze the associations key factors, including age, weight, menstrual cycle length, Anti-Mullerian Hormone (AMH) levels, follicle count, prevalence. Methods: A retrospective analysis was conducted on dataset of 539 participants determine optimal ranges these associated an increased likelihood diagnosis. Statistical analyses were using Python, correlation matrix, univariate multivariate logistic regression, evaluations. Results: Our findings demonstrated that risk increases positively in women under 32 years age. AMH levels above 4.18 ng/mL strongly PCOS, suggesting higher may reflect excessive follicular activity rather than enhanced ovarian function. Weight correlated emphasizing role metabolic disturbances its pathophysiology. Additionally, length exhibited non-linear association both shortened prolonged cycles being indicative hormonal dysregulation. count consistently linked reinforcing significance. Conclusions: provides evidence factors. The proposed serve as valuable reference points for clinicians, aiding early diagnosis personalized management strategies PCOS.

Language: Английский

Citations

1
The Anti-Mullerian Hormone as a Biomarker of Effectiveness of Metformin Hydrochloride Therapy in Polycystic Ovarian Syndrome and Insulin Resistance DOI Open Access
Nikoleta Parahuleva, Anna Mihaylova, Stanislava Harizanova

et al.

Healthcare, Journal Year: 2025, Volume and Issue: 13(8), P. 884 - 884

Published: April 11, 2025

Background/Objectives: Among the therapeutic options available for managing PCOS, metformin improves insulin sensitivity, reduces androgen levels, and helps restore menstrual regularity ovulation. While primarily used its metabolic effects, therapy may also influence reproductive parameters, including AMH which are pivotal in improving ovarian function predicting outcomes PCOS. The aim of this study was to search scientific literature analyze correlation between levels hydrochloride women with PCOS IR. Methods: A systematic review conducted using following keywords: polycystic syndrome, anti-Mullerian hormone, resistance, metformin, treatment, biomarker, syndrome. This aimed at investigating potential as a biomarker effectiveness patients Results: Metformin treatment has shown significant reductions serum prolonged therapy. As an sensitizer, hyperinsulinemia, suppresses hyperandrogenism. process inhibits growth antral follicles, is reflected decreased levels. Conclusions: Reductions improvements sensitivity can serve indicators efficacy enhancements these patients. could be considered prognostic marker evaluating decrease indicate improved reduction morphology. However, further research necessary confirm findings determine optimal dosages duration treatment.

Language: Английский

Citations

1
Nutritional and herbal interventions for polycystic ovary syndrome (PCOS): a comprehensive review of dietary approaches, macronutrient impact, and herbal medicine in management DOI Creative Commons
Aya A. Muhammed Saeed, Sobia Noreen, Farhang Hameed Awlqadr

et al.

Journal of Health Population and Nutrition, Journal Year: 2025, Volume and Issue: 44(1)

Published: May 2, 2025

Polycystic Ovary Syndrome (PCOS) is a common health condition related to woman's hormonal problems. Hormonal imbalance, metabolic disorders, and an increased insulin level mainly characterize the ailment. This detailed review focuses on dietary strategies, macromolecules, herbal interventions that exception-ally work in PCOS treatment. Research has shown Mediterranean, low-glycemic index, ketogenic diets are modified with individuals mind best ways resolve resistance, obesity, lack of ovulation. The other nutrients affect glucose metabolism play role hormone regulation such as protein reduced refined carbs. Among different micronutrients, vitamin D, omega-3 fatty acids, inositol were be most vital supplements treatment PCOS-induced oxidative damage, hyperandrogenism, infertility. Not mention, cinnamon, curcumin, sage, fennel, traditional Chinese medicine among some remedies so far show good potential perfect complementary therapy tools they create better glycemic control, inflammation reduction, menstrual cycle regularization. Even though findings promising, current supply clinical trials for standardizing these nutritional protocols lacking. Overall, this report stresses fact customized, holistic diet regime women make them feel well live long healthy life.

Language: Английский

Citations

0
Pharmacological and Non-Pharmacological Interventions for Polycystic Ovary Syndrome (PCOS) in Indian Women: A Systematic Review and Meta-Analysis DOI Creative Commons
Pratibha Maan, Rohit Gautam, Sudharsan Vasudevan

et al.

Pharmaceuticals, Journal Year: 2025, Volume and Issue: 18(5), P. 680 - 680

Published: May 2, 2025

Background: Polycystic ovary syndrome (PCOS) is an endocrine disorder prevalent in women of reproductive age. Treatment or management this includes several pharmacological and non-pharmacological treatment approaches for different manifestations the disease that vary with patient’s age, symptoms, requirements, geographical location. Objective: This systematic review aims to conduct a comprehensive evidence-based analysis various available options identify knowledge gaps PCOS India. Methods: A search was conducted PubMed, Scopus, Embase databases from January 2010 till February 2024. We included randomized control trials (RCTs) using any drugs (e.g., insulin sensitizers, anti-androgens, anti-obesity drugs, oral contraceptive pills, ovulation induction etc.) intervention yoga, diet, herbal supplements, Indian patients improving common written English language. Studies were screened by two authors independently two-level process. Data extraction also performed authors. Risk bias RoB 2 Tool. Subgroup meta-analysis RevMan tool. Results: Thirty RCTs on eight interventions study. However, all so heterogeneous terms used, subject recruited, outcomes measured possible only three subgroups (metformin vs. inositol, metformin metformin+ letrozole clomiphene citrate), studies per analysis. Most single-centric small-sized had high risk bias, limiting their generalizability. Conclusions: synthesized existing research evaluated effectiveness safety treatments. Limitations current identified, which may inform future better understanding context.

Language: Английский

Citations

0
The Role of Nutrition in Menstrual Cycle Regularity and the Management of Menstrual Disorder: A Review DOI

Harshita Gupta

Published: May 14, 2025

The menstrual cycle serves as a critical marker of women’s reproductive health and is intricately governed by hormonal interactions that are notably sensitive to external influences like diet. Recent studies emphasize the significant influence nutrition has on sustaining regularity mitigating disorders. A nutritionally balanced diet supports equilibrium, whereas poor eating habits frequently associated with disruptions. Conditions such polycystic ovary syndrome (PCOS), dysmenorrhea, premenstrual (PMS), functional hypothalamic amenorrhea have been linked inadequate dietary patterns. Diets high in refined sugars, Tran’s fats, processed items contribute insulin resistance fluctuations seen PCOS. In contrast, anti-inflammatory diets demonstrated benefits managing dysmenorrhea PMS symptoms, highlighting potential changes non-pharmacological strategy. Essential nutrients iron, magnesium, calcium, vitamin D, omega-3 fatty acids closely health. Iron replenishes blood loss, both magnesium B6 shown relieve symptoms. Vitamin D insufficiency correlates irregular menstruation PCOS risk. Mediterranean pattern, which fruits, vegetables, whole grains, healthy support balance, while high-glycemic severe calorie restriction may disrupt cycles trigger amenorrhea. This review emphasizes integral role plays regulation disorder management. Recognizing these connections can guide nutritional interventions enhance well-being holistic accessible manner. Further research essential create tailored guidelines for improving

Language: Английский

Citations

0