Breastfeeding Shapes the Gut Microbiota and Its Structure Is Associated with Weight Gain Trajectories in Mexican Infants DOI Open Access

Alejandra Arguelles-Lopez,

Sandra V. Aguayo-Patrón, Calderón de la Barca

et al.

Nutrients, Journal Year: 2025, Volume and Issue: 17(5), P. 826 - 826

Published: Feb. 27, 2025

Background: Rapid weight gain in early infancy increases the risk of childhood obesity, while exclusive breastfeeding can protect against it, depending on breastmilk composition, maternal diet, and infant gut microbiota. Objective: The objective this study was to analyze association between components, microbiota, first year life Mexican breastfed infants. Methods: This longitudinal included 27 mothers with exclusively infants (≥5 months age). We evaluated diet composition at 5 postpartum (pp), fecal microbiota 12 pp using 16S rRNA gene sequencing, as normal, rapid or slow (NWG, RWG SWG) periods 1 (0–5.5 months) 2 (5.5–12 months). Results: Infants NWG made up 51% 56%, respectively. In period 1, ingested protein content higher for than SWG (p = 0.01), negatively correlated BMI (r −0.42, p 0.02). genera Veillonella (19.5%), Bifidobacterium Escherichia-Shigella (16.8%) dominated months. At months, Bacteroides predominated, two remained. Breastmilk fat abundance −0.50, 0.02) oligosaccharides Lachnospiraceae 0.73, 0.03) There a trend other had Ruminococcus gnavus Alistipes Conclusions: Breastfeeding shaped infants, its structure associated trajectories.

Language: Английский

Breastfeeding Shapes the Gut Microbiota and Its Structure Is Associated with Weight Gain Trajectories in Mexican Infants DOI Open Access

Alejandra Arguelles-Lopez,

Sandra V. Aguayo-Patrón, Calderón de la Barca

et al.

Nutrients, Journal Year: 2025, Volume and Issue: 17(5), P. 826 - 826

Published: Feb. 27, 2025

Background: Rapid weight gain in early infancy increases the risk of childhood obesity, while exclusive breastfeeding can protect against it, depending on breastmilk composition, maternal diet, and infant gut microbiota. Objective: The objective this study was to analyze association between components, microbiota, first year life Mexican breastfed infants. Methods: This longitudinal included 27 mothers with exclusively infants (≥5 months age). We evaluated diet composition at 5 postpartum (pp), fecal microbiota 12 pp using 16S rRNA gene sequencing, as normal, rapid or slow (NWG, RWG SWG) periods 1 (0–5.5 months) 2 (5.5–12 months). Results: Infants NWG made up 51% 56%, respectively. In period 1, ingested protein content higher for than SWG (p = 0.01), negatively correlated BMI (r −0.42, p 0.02). genera Veillonella (19.5%), Bifidobacterium Escherichia-Shigella (16.8%) dominated months. At months, Bacteroides predominated, two remained. Breastmilk fat abundance −0.50, 0.02) oligosaccharides Lachnospiraceae 0.73, 0.03) There a trend other had Ruminococcus gnavus Alistipes Conclusions: Breastfeeding shaped infants, its structure associated trajectories.

Language: Английский

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