
Parasites & Vectors, Journal Year: 2024, Volume and Issue: 17(1)
Published: Dec. 23, 2024
Abstract Background Culex quinquefasciatus plays a crucial role as vector of West Nile virus (WNV). This mosquito species is widely distributed in Cape Verde, being found all inhabited islands the archipelago. However, no data are currently available on susceptibility local population to WNV. study aimed assess competence Cx. mosquitoes from Santiago Island, for WNV and explore potential impact its native Wolbachia transmission. Methods -infected uninfected female were exposed lineage 1 PT6.39 strain using Hemotek membrane feeding system. Mosquito samples, including body, legs, wings saliva, collected at days 7, 14 21 post-infection (dpi) infection through one-step quantitative real-time PCR (RT-qPCR). Results Verde exhibited high tested Also, treated females without their significantly higher load bodies greater dissemination rate 7 dpi than wild-type counterparts carrying . Conclusions The poses risk transmission this seems confer protection against early stages viral infection. Additional research required uncover mechanisms driving Graphical abstract
Language: Английский