Synergistic Anticandidal Effectiveness of Greenly Synthesized Zinc Oxide Nanoparticles with Antifungal Agents against Nosocomial Candidal Pathogens DOI Creative Commons
Mohamed Taha Yassin, Fatimah Al-Otibi, Abdulaziz A. Al‐Askar

et al.

Microorganisms, Journal Year: 2023, Volume and Issue: 11(8), P. 1957 - 1957

Published: July 31, 2023

The high prevalence of fungal resistance to antifungal drugs necessitates finding new combinations boost the bioactivity these agents. Hence, aim present investigation was greenly synthesize zinc oxide nanoparticles (ZnO-NPs) using an aqueous leaf extract Salvia officinalis and investigate their activity synergistic efficiency with common biofabricated ZnO-NPs were characterized detect physicochemical properties. A disk diffusion assay employed effectiveness synthesized evaluate patterns Candida tropicalis strain detected be most susceptible at both tested concentrations 50 100 µg/disk, demonstrating relative suppressive zones 19.68 ± 0.32 23.17 0.45 mm, respectively. minimum inhibitory concentration (MIC) against C. 40 µg/mL, whereas fungicidal (MFC) found 80 µg/mL. highest biogenic terbinafine agent glabrata strain, fluconazole albicans increases in fold inhibition area (IFA) values 6.82 1.63, Moreover, potential nystatin a IFA value 1.06. scanning electron microscopy (SEM) analysis affirmed morphological deformations candidal cells treated biosynthesized as formation abnormal infoldings cell wall membranes also pores membranes, which might lead leakage intracellular constituents. In conclusion, terbinafine, nystatin, strains highlights application formulating novel agents antimicrobial efficiency. ZnO exhibit powerful efficiency, prospective use formulation efficient medications, including mouthwash, ointments, lotions, creams for effective candidiasis treatment.

Language: Английский

Applications of Green Synthesized Metal Nanoparticles — a Review DOI Open Access
Seerengaraj Vijayaram, Hary Razafindralambo, Yun‐Zhang Sun

et al.

Biological Trace Element Research, Journal Year: 2023, Volume and Issue: 202(1), P. 360 - 386

Published: April 13, 2023

Language: Английский

Citations

267
Green synthesized silver nanoparticles: Optimization, characterization, antimicrobial activity, and cytotoxicity study by hemolysis assay DOI Creative Commons

Nida Liaqat,

Nazish Jahan,

Khalil-ur-Rahman

et al.

Frontiers in Chemistry, Journal Year: 2022, Volume and Issue: 10

Published: Aug. 29, 2022

Green nanotechnology has emerged as a viable option for the production of nanoparticles. The purpose current investigation was to synthesize silver nanoparticles (AgNPs) using Eucalyptus camaldulensis and Terminalia arjuna extracts, well their combinations, green reducing capping agents. parameters (concentration nitrate solution plant extract, time, pH, temperature) were optimized maximal yields, regulated size, stability ultraviolet-visible spectrophotometer (UV-Vis) surface plasmon resonance band (SPR) used validate synthesis AgNPs. shape, assessed zeta analyzer scanning electron microscope (SEM). biomolecules responsible reduction ion (Ag+) generated with extracts identified Fourier-transform infrared spectroscopy (FTIR). agar-well diffusion method test antimicrobial activity biosynthesized against Bacillus subtilis, Staphylococcus aureus, Pasteurella multocida, Escherichia coli. When 1 mM (AgNO3) added incubated 60 min at 75°C in neutral medium, maximum produced. Biosynthesized stable, spherical, monodispersed according potential microscopy. Silver synthesized combination 2 T. showed highest zone inhibition (16 mm) B. subtilis while 3 largest S. aureus (17 ± 0.8). It concluded that greenly produced good antibacterial causing negligible cytotoxicity.

Language: Английский

Citations

148
Biofabrication of nanoparticles: sources, synthesis, and biomedical applications DOI Creative Commons
Deepak Kulkarni, Rushikesh S. Sherkar,

Chaitali S. Shirsathe

et al.

Frontiers in Bioengineering and Biotechnology, Journal Year: 2023, Volume and Issue: 11

Published: May 2, 2023

Graphical Abstract Sources for biogenic synthesis: The synthesis sources include but are not limited to bacteria, fungi, algae, yeasts, marine and plant sources.

Language: Английский

Citations

118
Green Synthesis of Nanoparticles and Their Energy Storage, Environmental, and Biomedical Applications DOI Creative Commons
Hanaa M. Abuzeid, C. Julien, Likun Zhu

et al.

Crystals, Journal Year: 2023, Volume and Issue: 13(11), P. 1576 - 1576

Published: Nov. 8, 2023

Green synthesis offers a superior alternative to traditional methods for producing metal and oxide nanoparticles. This approach is not only benign safe but also cost-effective, scalable, straightforward, operating under ambient conditions. Notable metals nanoparticles, such as manganese oxides, iron silver, gold, have been produced using various bio-reductants derived from plant extracts. These biological agents expedite the reduction process stabilize serving dual roles reducing capping agents. review presents green of nanoparticles (NPs) obtained biogenic wastes The green-synthesized nanostructured MnO2 are evaluated potential photocatalyst water treatment an electrode material in lithium-ion batteries supercapacitors. green-derived examined promising antioxidant, anti-inflammatory, anti-diabetic Additionally, this discusses precious specifically silver (Ag NPs) gold (Au NPs), highlighting their medical applications areas like antiviral treatments cancer therapy.

Language: Английский

Citations

95
Limitations of nanomaterials insights in green chemistry sustainable route: Review on novel applications DOI Creative Commons
Kaushik Pal, Subhendu Chakroborty, Nibedita Nath

et al.

Green Processing and Synthesis, Journal Year: 2022, Volume and Issue: 11(1), P. 951 - 964

Published: Jan. 1, 2022

Abstract “Nanotechnology” is an emerging as a significant development tool for the green synthesis of noble nanomaterial. Green superior to conventional chemical methods it less expensive, reduced pollution, and enhances human health environment safety. Nanomaterial their from plants became interesting aspect nanotechnologies due many benefits they provide living beings, well low cost minimal harm humans environment. They also have wide range applications in biomedical research, diagnostics, drug discovery catalysis. The current review focuses on nanoparticle using greener approach novel applications.

Language: Английский

Citations

76
A critical review of microplastics in aquatic ecosystems: Degradation mechanisms and removing strategies DOI Creative Commons
Sameh S. Ali, Tamer Elsamahy,

Rania Al-Tohamy

et al.

Environmental Science and Ecotechnology, Journal Year: 2024, Volume and Issue: 21, P. 100427 - 100427

Published: April 25, 2024

Plastic waste discarded into aquatic environments gradually degrades smaller fragments, known as microplastics (MPs), which range in size from 0.05 to 5 mm. The ubiquity of MPs poses a significant threat ecosystems and, by extension, human health, these particles are ingested various marine organisms including zooplankton, crustaceans, and fish, eventually entering the food chain. This contamination threatens entire ecological balance, encompassing safety health systems. Consequently, developing effective MP removal technologies has emerged critical area research. Here, we summarize mechanisms recently reported strategies for removing ecosystems. Strategies combining physical chemical pretreatments with microbial degradation have shown promise decomposing MPs. Microorganisms such bacteria, fungi, algae, specific enzymes being leveraged remediation efforts. Recent advancements focused on innovative methods membrane bioreactors, synthetic biology, organosilane-based techniques, biofilm-mediated remediation, nanomaterial-enabled strategies, nano-enabled demonstrating substantial potential enhance efficiency. review aims stimulate further innovation methods, promoting environmental social well-being.

Language: Английский

Citations

19
Green synthesis, antioxidant and anticancer activities of TiO2 nanoparticles using aqueous extract of Tulbhagia violacea DOI Creative Commons

Yamkela Mbenga,

Jerry O. Adeyemi, Doctor Mziwenkosi Nhlanhla Mthiyane

et al.

Results in Chemistry, Journal Year: 2023, Volume and Issue: 6, P. 101007 - 101007

Published: June 20, 2023

In this study, titanium oxide nanoparticles represented as TiO2(1), TiO2(2), and TiO2(3) were prepared using different volumes (10, 20, 40 mL, respectively) of aqueous leaf extract Tulbhagia violacea. The physicochemical characteristics these materials established X-ray diffraction (XRD), ultraviolet-visible (UV-vis) spectroscopy, scanning electron microscopy (SEM), transmission (TEM), energy-dispersive spectroscopy. obtained XRD pattern confirmed the formation anatase TiO2 phase in all irrespective volume extracts used. Nevertheless, TiO2(2) 20 mL plant showed highest crystallinity. maximum absorption wavelength found region between 260 – 267 nm UV-vis spectroscopy study suggested a quantum size effect. All synthesized appeared to possess varying shapes sizes, mostly dominated by rectangular that irregularly distributed across materials. material was be highly agglomerated due high calcination temperature. antioxidant assay weak moderate activity relative standard ascorbic acid. Also, compared 5-Fluorouracil, exhibited cytotoxicity against HEK 293 HeLa cell lines. (1) best specificity towards cancer line with IC50 values 29.73 34.27 µg/mL for both lines, respectively. This suggests its potential promising candidate applications where it is important protect healthy cells.

Language: Английский

Citations

31
Nano-green: Harnessing the potential of plant extracts for sustainable antimicrobial metallic nanoparticles DOI

Pratibha Kaushal,

Dipak Maity, Rajendra Awasthi

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: 94, P. 105488 - 105488

Published: Feb. 17, 2024

Language: Английский

Citations

15
Breaking Barriers in Eco-Friendly Synthesis of Plant-Mediated Metal/Metal Oxide/Bimetallic Nanoparticles: Antibacterial, Anticancer, Mechanism Elucidation, and Versatile Utilizations DOI Open Access
Swati Dubey, Tarun Virmani, ShivKumar Yadav

et al.

Journal of Nanomaterials, Journal Year: 2024, Volume and Issue: 2024, P. 1 - 48

Published: April 12, 2024

Nanotechnology has emerged as a promising field in pharmaceutical research, involving producing unique nanoscale materials with sizes up to 100 nm via physiochemical and biological approaches. Nowadays more emphasis been given eco-friendly techniques for developing nanomaterials enhance their applications minimize health environmental risks. With the help of green nanotechnology, wide range metal, metal oxide, bimetallic nanoparticles distinct chemical compositions, sizes, morphologies have manufactured which are safe, economical, environment friendly. Due biocompatibility vast potential biomedical (antibacterial, anticancer, antiviral, analgesic, anticoagulant, biofilm inhibitory activity) other fields such (nanofertilizers, fermentative, food, bioethanol production, construction field), garnered significant interest worldwide. The precursors combined natural extracts plants, algae, fungi, bacteria get potent novel Ag, Au, Co, Cu, Fe, Zr, Zn, Ni, Pt, Mg, Ti, Pd, Cd, Bi2O3, CeO2, Co3O4, CoFe2O4, CuO, Fe2O3, MgO, NiO, TiO2, ZnO, ZrO2, Ag-Au, Ag-Cr, Ag-Cu, Ag-Zn, Ag-CeO2, Ag-CuO, Ag-SeO2, Ag-TiO2, Ag-ZnO, Cu-Ag, Cu-Mg, Cu-Ni, Pd-Pt, Pt-Ag, ZnO-CuO, ZnO-SeO, ZnO-Se, Se-Zr, Co-Bi2O3. These plant-mediated possess excellent antibacterial anticancer activity when tested against several microorganisms cancer cell lines. Plants contain essential phytoconstituents (polyphenols, flavonoids, terpenoids, glycosides, alkaloids, etc.) compared sources (bacteria, algae) higher concentration that play vital role development because these plant-phytoconstituents act reducing, stabilizing, capping agent helps nanoparticles. After concluding all findings, this review designed first time way it imparts satisfactory knowledge about together, along mechanisms. Additionally, provides information characterization (UV–vis, FT-IR, DLS, XRD, SEM, TEM, BET, AFM) employed nanoparticles, applications, industries. Hence, various types versatile application diverse is not covered pieces literature.

Language: Английский

Citations

14
Progress in the Sustainable Development of Biobased (Nano)materials for Application in Water Treatment Technologies DOI Creative Commons
Asif Saud, Soumya Gupta,

Ahmed Allal

et al.

ACS Omega, Journal Year: 2024, Volume and Issue: 9(27), P. 29088 - 29113

Published: June 27, 2024

Water pollution remains a widespread problem, affecting the health and wellbeing of people around globe. While current advancements in wastewater treatment desalination show promise, there are still challenges that need to be overcome make these technologies commercially viable. Nanotechnology plays pivotal role water purification processes today. However, release nanoparticles (NPs) into environment without proper safeguards can lead both physical chemical toxicity. Moreover, many methods NP synthesis expensive not environmentally sustainable. The utilization biomass as source for production NPs has potential mitigate issues pertaining cost, sustainability, pollution. biobased nanomaterials (bio-NMs) sourced from garnered attention field due their cost-effectiveness, biocompatibility, biodegradability. Several research studies have been conducted efficiently produce (both inorganic organic) applications treatment. Biosynthesized materials such zinc oxide NPs, phytogenic magnetic biopolymer-coated metal cellulose nanocrystals, silver among others, demonstrated efficacy enhancing process purification. friendly presents viable option efficiency sustainability eradication. present review delves topic biomass, its origins, by which it transformed utilizing an sustainable approach. study will examine greener contemporary technologies.

Language: Английский

Citations

14