Polymers,
Journal Year:
2024,
Volume and Issue:
17(1), P. 18 - 18
Published: Dec. 25, 2024
The
grapevine
industry
is
confronted
with
challenges
such
as
plant
stress
from
environmental
factors
and
microbial
infections,
alongside
the
need
for
sustainable
waste
management
practices.
Natural
polymers
offer
promising
solutions
to
these
issues
due
their
biocompatibility,
biodegradability,
functional
versatility.
This
review
explores
dual
role
of
natural
in
enhancing
industry:
protective
agents
against
various
stressors
carriers
delivery
valuable
compounds
recovered
wastes.
We
examine
use
chitosan,
alginate,
cellulose
formulating
bio-based
coatings
treatments
that
bolster
resistance
abiotic
stress,
pathogens,
pests.
Additionally,
delves
into
innovative
utilization
residues,
including
skins,
seeds,
stems,
sources
polyphenols
other
bioactive
compounds.
These
can
be
efficiently
encapsulated
polymer
matrices
applications
agriculture,
food,
pharmaceuticals.
Key
topics
include
mechanisms
action,
benefits,
limitations
polymer-based
interventions,
well
case
studies
demonstrating
practical
implementation
vineyards.
also
addresses
future
research
directions,
emphasizing
integrated
approaches
enhance
sustainability
economic
viability
industry.
Molecules,
Journal Year:
2025,
Volume and Issue:
30(9), P. 2073 - 2073
Published: May 7, 2025
Morus
alba
L.
(Moraceae),
white
mulberry,
is
an
ancient,
well-known
source
of
several
compounds
with
potent
biological
activities
and
beneficial
effects
on
human
health.
In
this
study,
the
juices
three
stabilised
undifferentiated
cell
lines,
calli
maintained
in
light
dark
conditions,
suspensions
condition
M.
were
investigated
for
their
phytochemical
content
activity.
The
results
highlighted
main
presence
oxyresveratrol
resveratrol-backbone
glucosides,
together
benzofuran
derivatives.
Oxyresveratrol
triglucoside
was
found
first
time
vitro
cultures,
where
it
represents
compound,
accounting
almost
90
µg/mL
all
juices.
total
stilbenoid
resulted
significantly
higher
during
logarithmic
phase
growth
cycle,
suspension
juice
exhibited
statistically
highest
(313.21
juice).
Only
showed
ROS
reduction
Caco-2
cells,
whereas
reduced
IL-1β
TNF-α
levels
cells
stimulated
LPS.
These
lay
groundwork
future
exploitation
dedifferentiated
cultures
as
sustainable
resources
to
be
used
nutraceutical,
cosmetic,
pharmaceutical
industries.
Frontiers in Bioengineering and Biotechnology,
Journal Year:
2025,
Volume and Issue:
13
Published: May 9, 2025
Mesenchymal
stem
cells
(MSCs)
have
the
potential
to
differentiate
into
various
cell
types,
providing
important
sources
of
for
development
regenerative
medicine.
Although
MSCs
advantages,
there
are
also
problems,
such
as
low
survival
rate
transplanted
and
poor
migration
homing;
therefore,
determining
how
reform
improve
their
utilization
is
particularly
important.
many
natural
bioactive
compounds
shown
great
improving
MSCs,
mechanisms
pathways
involved;
however,
in
final
analysis,
promoted
MSC
proliferation,
homing
differentiation
antiaging.
This
article
reviews
regulatory
effects
on
provide
new
ideas
therapeutic
modified
diseases.
Fermentation,
Journal Year:
2023,
Volume and Issue:
9(9), P. 838 - 838
Published: Sept. 13, 2023
The
plethora
of
bio-functional
compounds
present
in
fermented
alcoholic
beverages
like
wine,
as
well
the
valorisation
bioactives
from
wineries’/breweries’
by-products
grape
pomace
and
seed,
has
gained
significant
interest
functional
foods
sector.
This
beverage,
always
accompanied
humanity,
for
religion
or
health,
especially
Mediterranean,
while
benefits
its
moderate
consumption
were
documented
even
by
Greek
physician
Hippocrates
Kos
(460–370
BC).
After
a
big
gap,
an
outbreak
research
on
wine
surfaced
only
since
1990s,
when
term
“French
paradox”
was
introduced
to
US
public
during
CBS
show,
recent
evidence
outlined
that
beneficial
effects
are
derived
synergisms
their
digestion-derived
metabolites.
Within
this
article,
proposed
health
consumption,
component
balanced
diet
(i.e.,
Mediterranean
diet)
against
inflammation-related
chronic
disorders,
is
thoroughly
reviewed.
various
both
wineries’
by-products,
such
bioactive
phenolics,
unsaturated
fatty
acids,
polar
lipids
dietary
fibres,
antioxidant,
anti-inflammatory
antithrombotic
health-promoting
properties,
also
evaluated.
mechanisms
action
synergism,
which
elicited,
explored.
Functional
properties
non-alcoholic
products
introduced.
Emphasis
given
applications
bioactives,
ingredients
foods,
supplements
nutraceuticals.
Limitations
future
perspectives
popular
beverage
(wine)
rich
addressed.
ACS Applied Materials & Interfaces,
Journal Year:
2024,
Volume and Issue:
16(38), P. 50442 - 50458
Published: Sept. 16, 2024
Respiratory
syncytial
virus
(RSV)-induced
viral
pneumonia
in
children
is
common
worldwide.
Its
high
occurrence
and
lack
of
an
effective
vaccine
make
it
a
leading
cause
death
children.
Severe
RSV
infection
can
trigger
uncontrolled
inflammatory
responses
patients,
so
the
development
small
molecule
drugs
with
dual
function
"direct
antivirus"
"inflammatory
response
regulation"
welcome.
Resveratrol
(Res)
has
been
reported
to
have
antiviral
anti-inflammatory
pharmacological
effects,
but
its
application
limited
because
poor
water
solubility
oral
bioavailability.
Based
on
small-molecule
nanotechnology,
we
developed
sonication-assisted
self-assembly
method
for
preparing
insoluble
Res
into
highly
soluble
resveratrol
nanoparticles
(Res
NPs).
The
obtained
NPs
exhibited
higher
faster
dissolution
rate,
which
was
more
conducive
effectiveness
addressing
RSV-induced
pneumonia.
In
vitro
studies
had
shown
that
played
role
by
inhibiting
replication
reducing
production
pro-inflammatory
cytokines.
Nebulized
inhalation
administration
prolonged
drug's
residence
time
lungs,
appears
increase
accumulation
NPs.
Additionally,
vivo
demonstrated
significant
benefits
load
improving
pulmonary
microenvironment
RSV-infected
mice.
Both
experiments
confirmed
activity
superior
Res.
This
suggested
nanosizing
way
enhance
original
also
offered
new
formulation
strategy
treating
Polymers,
Journal Year:
2024,
Volume and Issue:
17(1), P. 18 - 18
Published: Dec. 25, 2024
The
grapevine
industry
is
confronted
with
challenges
such
as
plant
stress
from
environmental
factors
and
microbial
infections,
alongside
the
need
for
sustainable
waste
management
practices.
Natural
polymers
offer
promising
solutions
to
these
issues
due
their
biocompatibility,
biodegradability,
functional
versatility.
This
review
explores
dual
role
of
natural
in
enhancing
industry:
protective
agents
against
various
stressors
carriers
delivery
valuable
compounds
recovered
wastes.
We
examine
use
chitosan,
alginate,
cellulose
formulating
bio-based
coatings
treatments
that
bolster
resistance
abiotic
stress,
pathogens,
pests.
Additionally,
delves
into
innovative
utilization
residues,
including
skins,
seeds,
stems,
sources
polyphenols
other
bioactive
compounds.
These
can
be
efficiently
encapsulated
polymer
matrices
applications
agriculture,
food,
pharmaceuticals.
Key
topics
include
mechanisms
action,
benefits,
limitations
polymer-based
interventions,
well
case
studies
demonstrating
practical
implementation
vineyards.
also
addresses
future
research
directions,
emphasizing
integrated
approaches
enhance
sustainability
economic
viability
industry.