Natural Products as Drug Candidates for Redox-Related Human Disease DOI Creative Commons
Jong H. Kim, Kirkwood M. Land, Canhua Huang

et al.

Pharmaceuticals, Journal Year: 2023, Volume and Issue: 16(9), P. 1294 - 1294

Published: Sept. 13, 2023

This Special Issue presented recent progress on natural products that serve as drug candidates for redox-related human diseases [...]

Language: Английский

Mesoporous zinc-polyphenol nanozyme for attenuating renal ischemia–reperfusion injury DOI

Zepeng Li,

J. Qin,

Youyou Feng

et al.

Nanomedicine, Journal Year: 2024, Volume and Issue: 19(24), P. 2011 - 2026

Published: Aug. 8, 2024

To target the reactive oxygen species (ROS) accumulation and renal tubular epithelial cell (rTEC) death in ischemia-reperfusion injury (IRI), we constructed a nanoparticle that offers ROS scavenging rTEC-death inhibition: mesoporous zinc-tannic acid nanozyme (ZnTA).

Language: Английский

Citations

0
Synthetic and Natural Drug Nanodelivery Systems Used in Oncology Treatment DOI

Nadia Talin Mirakian,

Daniela L. Papademetrio, Valeria P. Sülsen

et al.

Interdisciplinary cancer research, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Language: Английский

Citations

0
Innovative nanocarrier systems for enhanced delivery of phyto-active compounds in cancer therapy DOI
Khusbu Dwivedi, Ankit Sahoo, Waleed Hassan Almalki

et al.

Nanomedicine, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 26

Published: Dec. 20, 2024

Millions of people worldwide suffer from cancer, facing challenges such as treatments affecting healthy cells, suboptimal responses, adverse effects, recurrence risk, drug resistance, and nonspecific targeting. Chemoresistance leads to fatalities, but phytoactives show promise in cancer management despite limitations high metabolism, poor absorption, dosage requirements. Challenges the large-scale isolation phytoactive compounds, solubility, bioavailability, targeting limit their development. Recent developments, including carbohydrate, lipid, protein-based nanoparticles, have enhanced treatment by improving bioavailability targeted delivery polyphenols, alkaloids, sulfur-containing flavonoids, terpenes. Despite advancements, clinical application faces hurdles inconsistent immune responses. This article discusses phytoactive-loaded nanoformulations management, highlighting delivery, unmet needs, challenges. Further research is needed overcome these fully understand potential management.

Language: Английский

Citations

0
Natural Products as Drug Candidates for Redox-Related Human Disease DOI Creative Commons
Jong H. Kim, Kirkwood M. Land, Canhua Huang

et al.

Pharmaceuticals, Journal Year: 2023, Volume and Issue: 16(9), P. 1294 - 1294

Published: Sept. 13, 2023

This Special Issue presented recent progress on natural products that serve as drug candidates for redox-related human diseases [...]

Language: Английский

Citations

1