Antioxidant potential, antimicrobial activity, polyphenol profile analysis, and cytotoxicity against breast cancer cell lines of hydro-ethanolic extracts of leaves of (Ficus carica L.) from Eastern Morocco

Frontiers in Chemistry, Journal Year: 2024, Volume and Issue: 12

Published: Nov. 27, 2024

Many beneficial compounds found in fig leaves can be used tea and medicine. These aid with digestion, reduce inflammation, treat diabetes bronchitis. Chetoui, Malha, Ghoudane, Onk Hmam leaf hydro-ethanol extracts from Eastern Morocco were analyzed for metabolites biological activities.

Language: Английский

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Biological Activities of Ceratonia siliqua Pod and Seed Extracts: A Comparative Analysis of Two Cretan Cultivars

International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 24(15), P. 12104 - 12104

Published: July 28, 2023

Ceratonia siliqua L., commonly known as the carob tree, appears in most Mediterranean countries, often cultivated for collection of its fruits to be used food humans and animals. This study was aimed at phytochemical characterization two common Cretan C. cultivars biological evaluation deseeded pod seed extracts regarding their putative use cosmetics. Gas liquid chromatographic techniques were assess essential oil, fatty acid, carbohydrate profiles. Cell-free assays, including free-radical scavenging; inhibition tyrosinase collagenase; blocking advanced glycation end product (AGE) formation; along with assays human skin fibroblast cultures, i.e., reactive oxygen species suppression, glutathione stimulation, protection from oxidative stress ultraviolet (UVB) radiation, also used. Extracts both found possess antioxidant capacity, tyrosinase- collagenase-inhibitory activities, an ability block glucose-induced AGEs, certain cases, UVB absorbance photoprotective activities. Seed general more active, while 30% aqueous methanol seemed efficient than n-hexane extraction. Serial partition active resulted fractions enriched These properties make suitable candidates

Language: Английский

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Screening of Phytochemical, Antimicrobial, and Antioxidant Properties of Juncus acutus from Northeastern Morocco

Life, Journal Year: 2023, Volume and Issue: 13(11), P. 2135 - 2135

Published: Oct. 29, 2023

Juncus acutus, acknowledged through its indigenous nomenclature "samar", is part of the Juncaceae taxonomic lineage, bearing considerable import as a botanical reservoir harboring conceivable therapeutic attributes. Its historical precedence in traditional curative methodologies for alleviation infections and inflammatory conditions notable. In purview Eastern medicine, species seeds find application their remedial efficacy addressing diarrhea, while fruits are subjected to infusion processes targeting attenuation symptoms associated with cold manifestations. The primary objective this study was unravel phytochemical composition distinct constituents within J. specifically leaves (JALE) roots (JARE), originating from expanse Nador region northeastern Morocco. extraction plant executed utilizing an ethanol-based protocol. subsequent elucidation chemical embedded extracts accomplished employing analytical techniques based on high-performance liquid chromatography (HPLC). For purpose vitro antioxidant evaluation, dual approach adopted, encompassing radical scavenging technique 2,2-diphenyl-1-picrylhydrazyl (DPPH) total capacity (TAC) assay. acquired empirical data showcase substantial pronounced relative activity. Specifically, DPPH TAC methods yielded values 483.45 ± 4.07 µg/mL 54.59 2.44 µg ascorbic acid (AA)/mL, respectively, leaf extracts. Correspondingly, root demonstrated 297.03 43.3 65.615 0.54 AA/mL methods. realm antimicrobial assessment effects undertaken agar well diffusion technique. minimum inhibitory concentration, bactericidal fungicidal concentration were determined each extract. influence ethanol observed across bacterial strains including Staphylococcus aureus, Micrococcus luteus, Pseudomonas aeruginosa, notable exception Escherichia coli. However, fungal such Candida glabrata Rhodotorula glutinis exhibited comparatively lower resistance, whereas Aspergillus niger Penicillium digitatum heightened evincing negligible antifungal An anticipatory computational pharmacokinetic parameters conducted, complemented by Pro-tox II web tool delineate potential toxicity profile compounds intrinsic studied culmination these endeavors underpins prospects investigated promising candidates oral medicinal applications.

Language: Английский

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International Biological Flora: Ceratonia siliqua

Journal of Ecology, Journal Year: 2024, Volume and Issue: 112(8), P. 1885 - 1922

Published: May 20, 2024

Abstract This account presents information on all aspects of the biology Ceratonia siliqua L. (Carob) that are relevant to understanding its ecological characteristics and behaviour. The main topics presented within standard framework International Biological Flora : distribution, habitat, communities, responses biotic factors, environment, structure physiology, phenology, floral seed characters, herbivores disease, history conservation. is a lowland evergreen shrub or tree, native around Mediterranean basin widely cultivated in areas with warm temperate subtropical climate, more than 100 named cultivars. Carob grows wide range soils including nutrient‐poor strongly calcareous, dry soils. dioecious rarely hermaphrodite although females dominate cultivation due their fruit. Pollination primarily by insects relatively large seeds spread mainly ingestion fruits mammals. Seed dormancy imposed hard coat germinate readily after natural artificial scarification. Drought tolerance very high, acting as drought avoiding water spender. also tolerant saline conditions fire can act restrict wildfire generating fuel discontinuity. It shows high post‐fire regrowth. Old individuals house diversity associated fauna comparatively unaffected serious pests diseases. has long cultural food source for humans domesticated animals, herbal modern medicine and, recently, carob bean gum used variety domestic products foods. Commercial production declined over past decades but low care needed growing orchards, potential new markets fruit seeds, use tree prevent soil erosion sequester carbon gives brighter future.

Language: Английский

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A Study of the Bioactive Compounds, Antioxidant Capabilities, Antibacterial Effectiveness, and Cytotoxic Effects on Breast Cancer Cell Lines Using an Ethanolic Extract from the Aerial Parts of the Indigenous Plant Anabasis aretioïdes Coss. & Moq.

Current Issues in Molecular Biology, Journal Year: 2024, Volume and Issue: 46(11), P. 12375 - 12396

Published: Nov. 1, 2024

contain numerous bioactive compounds that provide several advantages, including antioxidant, antibacterial, anticancer, neuroprotective, anti-inflammatory, and antidiabetic characteristics. This study aimed to make a hydroethanolic extract from the aerial part of plant, analyze its biochemical compounds, test biological activities. From HPLC-DAD analysis, cinnamic acid, sinapic vanillin bioactives were found be main in extract. The spectrometric tests revealed was rich flavonoids (8.52 ± 0.32 mg RE/100 g DW), polyphenols (159.32 0.63 GAE/100 condensed tannins (8.73 0.23 CE/100 DW). showed significant antioxidant activity. There strong correlations between amount flavonoid or polyphenol assays, ABTS, DPPH, β-carotene, TAC. also highly effective results against Gram-positive bacteria

Language: Английский

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