Advances in Animal and Veterinary Sciences,
Journal Year:
2023,
Volume and Issue:
11(10)
Published: Jan. 1, 2023
The
aim
of
this
project
to
study
the
effect
combination
between
ciprofloxacin
and
diclofenac
alone
in
treating
urinary
tract
infection
caused
by
Escherichia
coli
(0157):H7.Samples
were
collected
for
purpose
isolation
diagnosis
resist.E.
0157:H7
two
hundred
urine
samples
from
adult
women
patients
suffering
UTIs
during
a
period
February
2022
July
Diwaniyah
city
Iraq
.All
incubated
aerobically
at
37°C
24-48
hrs
on
blood
agar,
MacConkey
agar
as
well
biochemical
tests
identified
special
media
isolates.The
isolates
confirmed
diagnosed
Vitek
assay.In
study,
forty-eighth
female
rabbit
aged
(6-8
weeks)
weighing
(1500
2000)
gm.,
was
randomly
divided
into
six
equal
groups(8/each)
follow
positive
control(PC)
,
negative
control(NC)
1mg/kg(DC),
7
mg/kg(CIP),
(ciprofloxacin
3.5
mg/kg+diclofenac1mg/kg)
COM1
combination(ciprofloxacin
1.75
mg/kg+diclofenac
1mg/kg)
com2
groups
all
injection
0.1
ml
1
x
10
9
CFU
E
0157
:H7
catheterization
route
excepting
control
resulted
significant
increase(P<
0.05)
white
cells,
monocyte,
neutrophils
after
three
days
comparison
with
experimental
(14
days)
which
increase
(P<
(P.C.).However,(D-C,COM1,COM2)
decrease
values
(seven,
fourteen)
PC
CIP
groups.diclofenac
can
be
used
antibiotics
an
anti-virulence
agent
will
enhance
ability
immune
system
eradicate
infection.In
histopathological
examination
clear
damage
kidney
tissue
specimens
group
(PC,DC)
observed,
hyperplasia
endothelial
cell
swelling,
ulcer
lining
membrane,
compared
with(CIP,COM1and
COM2).Altogether,
we
conclude
that
has
required
anti-boiflim
effects
support
body
responses
against
consequences
o157
BIO Integration,
Journal Year:
2024,
Volume and Issue:
5(1)
Published: Jan. 1, 2024
Abstract
Background:
Nitrofurantoin
is
a
BCS
II
drug
with
low
solubility
and
dissolution
rate.
Therefore,
the
pharmaceutical
applications
of
nitrofurantoin
are
limited.
The
purpose
current
study
was
to
enhance
solubility,
dissolution,
bioavailability
by
formulating
solid
dispersion
(SD).
Methods:
SD
developed
using
3
2
factorial
designs
considering
poloxamer
188
trituration
time
as
independent
variables,
release
dependent
variables.
characterized
for
FTIR,
DSC,
XRD,
in
vitro
pharmacokinetic
studies
rats.
Results:
Nitrofurantoin:poloxamer
at
1:1
ratio
had
higher
than
nitrofurantoin.
directly
related
amount
time.
In
addition,
concentration
DR
45
(%),
while
rate
stirring
inversely
(%).
An
FTIR
revealed
excellent
excipient
compatibility.
crystallinity
decreased,
which
indicated
more
amorphous
nature
XRD
DSC
studies.
Compared
pure
dispersion,
optimized
formulation
exhibited
3.88-fold
improvement
nitrofurantoin,
whereas
compared
marketed
formulation,
1.77-fold
enhancement
noted.
Conclusion:
This
that
could
be
potential
carrier
system
Expert Opinion on Drug Safety,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 13, 2024
Drug-induced
urinary
retention
(DIUR)
can
severely
impact
patient
quality
of
life
and
complicate
treatment.
This
study
investigates
the
incidence
characteristics
DIUR
using
data
from
FDA
Adverse
Event
Reporting
System
(FAERS)
over
20
years.
Journal of Intellectual Disability Research,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 24, 2024
ABSTRACT
Background
Urinary
and
bowel
incontinence
are
more
common
in
adults
with
intellectual
disability
(ID),
compared
to
the
general
population.
Little
is
known
about
their
experiences
toileting
issues.
The
aim
was
learn
Method
Incontinence
issues
assessment
conducted
a
community‐based
sample
of
22
ID
urinary
incontinence,
or
without
incontinence.
Assessment
included
IPSS
,
ICIQ‐UI
POTI
checklists;
bladder
scans;
urine
screening
for
presence
tract
infection.
Results
majority
(19
adults,
86%)
developed
during
adulthood.
Seven
(32%)
also
experienced
constipation
most
commonly
reported
health
condition
(13
59%),
other
than
Fifty
per
cent
(11
adults)
had
been
treated
infection
within
previous
12
months.
Conclusion
There
an
urgent
need
develop
accessible
reliable
materials
supporters.
These
assessments
should
pay
close
attention
conditions
that
can
cause
this
group
factors
associated
which
by
ID.
potentially
modifiable.
Česká a slovenská farmacie,
Journal Year:
2024,
Volume and Issue:
73(1), P. 48 - 56
Published: March 19, 2024
Pharmaceutical
care
in
the
self-treatment
of
common
urological
problems
In
case
disorders,
a
pharmacist
or
pharmacy
assistant
is
often
first
healthcare
professional
patient
turns
to.
Appropriate
information
should
be
obtained
from
interview
with
to
distinguish
between
symptoms
and
conditions
suitable
for
and,
conversely,
recommend
visit
physician.
The
contact
professionals
can
also
contribute
detection
more
serious
diseases.
article
deals
possibilities
pharmaceutical
difficulties
requirement
recommendation
self-treatment,
focusing
on
understanding
individual
symptoms,
their
differentiation,
principles
identification
situations
unsuitable
self-treatment.
Advances in Animal and Veterinary Sciences,
Journal Year:
2023,
Volume and Issue:
11(10)
Published: Jan. 1, 2023
The
aim
of
this
project
to
study
the
effect
combination
between
ciprofloxacin
and
diclofenac
alone
in
treating
urinary
tract
infection
caused
by
Escherichia
coli
(0157):H7.Samples
were
collected
for
purpose
isolation
diagnosis
resist.E.
0157:H7
two
hundred
urine
samples
from
adult
women
patients
suffering
UTIs
during
a
period
February
2022
July
Diwaniyah
city
Iraq
.All
incubated
aerobically
at
37°C
24-48
hrs
on
blood
agar,
MacConkey
agar
as
well
biochemical
tests
identified
special
media
isolates.The
isolates
confirmed
diagnosed
Vitek
assay.In
study,
forty-eighth
female
rabbit
aged
(6-8
weeks)
weighing
(1500
2000)
gm.,
was
randomly
divided
into
six
equal
groups(8/each)
follow
positive
control(PC)
,
negative
control(NC)
1mg/kg(DC),
7
mg/kg(CIP),
(ciprofloxacin
3.5
mg/kg+diclofenac1mg/kg)
COM1
combination(ciprofloxacin
1.75
mg/kg+diclofenac
1mg/kg)
com2
groups
all
injection
0.1
ml
1
x
10
9
CFU
E
0157
:H7
catheterization
route
excepting
control
resulted
significant
increase(P<
0.05)
white
cells,
monocyte,
neutrophils
after
three
days
comparison
with
experimental
(14
days)
which
increase
(P<
(P.C.).However,(D-C,COM1,COM2)
decrease
values
(seven,
fourteen)
PC
CIP
groups.diclofenac
can
be
used
antibiotics
an
anti-virulence
agent
will
enhance
ability
immune
system
eradicate
infection.In
histopathological
examination
clear
damage
kidney
tissue
specimens
group
(PC,DC)
observed,
hyperplasia
endothelial
cell
swelling,
ulcer
lining
membrane,
compared
with(CIP,COM1and
COM2).Altogether,
we
conclude
that
has
required
anti-boiflim
effects
support
body
responses
against
consequences
o157
