Putative Role of Adenosine A1 Receptors in Exogenous Ketone Supplements-Evoked Anti-Epileptic Effect
International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(18), P. 9869 - 9869
Published: Sept. 12, 2024
Approximately
30%
of
patients
with
epilepsy
are
drug-refractory.
There
is
an
urgent
need
to
elucidate
the
exact
pathophysiology
different
types
epilepsies
and
mechanisms
action
both
antiseizure
medication
metabolic
therapies
treat
more
effectively
safely.
For
example,
it
has
been
demonstrated
that
exogenous
ketone
supplement
(EKS)-generated
therapeutic
ketosis,
as
a
therapy,
may
decrease
epileptic
activity
in
animal
models
humans,
but
its
mechanism
unknown.
However,
was
among
others,
can
increase
adenosine
level,
which
enhance
A1
receptors
(A
Language: Английский
Exploring diet-induced ketosis with exogenous ketone supplementation as a potential intervention in post-traumatic stress disorder: a feasibility study
Frontiers in Nutrition,
Journal Year:
2024,
Volume and Issue:
11
Published: Oct. 31, 2024
Post-Traumatic
Stress
Disorder
(PTSD)
is
a
severe
and
pervasive
mental
disorder,
patients
experience
numerous
distressing
symptoms
impairments
that
significantly
impact
their
lives.
In
addition
to
being
PTSD
strongly
associated
with
wide
range
of
metabolic
abnormalities
affect
the
entire
body.
Existing
treatment
options
psychotherapy
medications
are
often
ineffective.
Exploring
other
potential
treatments
necessitated.
The
ketogenic
diet
has
shown
as
therapy
in
certain
neurological
disorders
promising
intervention
PTSD.
Language: Английский