Anti-cancer efficiency of Campylobacter jejuni secretome loaded chitosan nanoparticles on colorectal cancer signaling pathways DOI

Ghazale Khodadadi,

Masoumeh Saberpour,

Bita Bakhshi

et al.

Cytotechnology, Journal Year: 2025, Volume and Issue: 77(3)

Published: April 28, 2025

Language: Английский

Chitosan Approaches in Colon Cancer Therapy: Understanding its Macromolecular Interactions and Structure-Property Relationships DOI
Sankha Bhattacharya, Dilpreet Singh

Journal of Macromolecular Science Part B, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 12

Published: Jan. 9, 2025

Colon cancer is still a significant cause of cancer-related deaths and, therefore, new treatment approaches are required. As naturally derived polysaccharide, Chitosan has become one the most promising materials in polymer-based drug delivery systems because its outstanding biocompatibility, biodegradability, and pH-responsive release. This review explores expanding roles chemical modifications colon therapy, emphasizing relationship between macromolecular interactions structure-property dynamics. Recent progress Chitosan-based nanocarriers, including nanoparticles, nanogels hybrid systems, highlights their potential to overcome multidrug resistance minimize off-target toxicity. These advancements closely aligned with developments precision medicine, incorporating stimuli-responsive components targeted ligands for enhanced efficacy. While preclinical clinical studies yield results, critical challenges such as scalability, reproducibility regulatory compliance remain obstacles translation. emphasizes transformative addressing therapeutic barriers treatment. Looking ahead, future should focus on utilizing cutting-edge technologies, artificial intelligence 3D bioprinting, enhance formulations develop personalized solutions that more effective tailored individual needs.

Language: Английский

Citations

1
Advanced therapeutic strategies using Thermo-sensitive chitosan/pectin hydrogel in the treatment of multiple cancers DOI
Tosha Pandya,

Disha Joshi,

Zenab Presswala

et al.

Carbohydrate Polymers, Journal Year: 2025, Volume and Issue: 357, P. 123454 - 123454

Published: Feb. 27, 2025

Language: Английский

Citations

0
Metal ion crosslinked polysaccharide hydrogels: A review on their potential for therapeutic delivery and tissue engineering DOI

Riya Hazra,

Md Sahil Shanawaz Alam,

Ashim Malakar

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 310, P. 143467 - 143467

Published: April 23, 2025

Language: Английский

Citations

0
Anti-cancer efficiency of Campylobacter jejuni secretome loaded chitosan nanoparticles on colorectal cancer signaling pathways DOI

Ghazale Khodadadi,

Masoumeh Saberpour,

Bita Bakhshi

et al.

Cytotechnology, Journal Year: 2025, Volume and Issue: 77(3)

Published: April 28, 2025

Language: Английский

Citations

0