Pharmaceutics, Journal Year: 2022, Volume and Issue: 14(12), P. 2827 - 2827
Published: Dec. 16, 2022
Current advances in biomaterials processing and engineering for drug delivery have allowed interesting progressed biomedical field [...]
Language: Английский
Journal of Drug Delivery Science and Technology, Journal Year: 2023, Volume and Issue: 89, P. 104985 - 104985
Published: Oct. 2, 2023
Language: Английский
Citations
9
Elsevier eBooks, Journal Year: 2023, Volume and Issue: unknown, P. 505 - 520
Published: Jan. 1, 2023
Language: Английский
Citations
3
Current Topics in Medicinal Chemistry, Journal Year: 2022, Volume and Issue: 22(11), P. 922 - 938
Published: March 4, 2022
Cancer is a multistage process that numerous modalities including systemic treatment can treat. About half of the molecules have been approved in last few decades count for plant derivatives. This review presents application tree/shrub-derived biologically active compounds as anticancer agents. Different parts trees/shrubs - wood, bark, branches, roots, leaves, needles, fruits, flowers, etc. contain wide variety primary and secondary metabolites demonstrate properties. Special attention was paid to phenolics (phenolic acids polyphenols, flavonoids non-flavonoids (tannins, lignans, stilbenes)), essential oils, their main constituents such terpenes/terpenoids, phytosterols, alkaloids, many others. The properties these are mainly attributed strong antioxidant In vitro experiments on various cancer cell lines revealed cytotoxic effect tree-derived extracts. Mechanisms action extracts also listed. Examples drugs successfully underwent clinical trials with well-established positions guidelines created by oncological societies provided. focuses directions future development agents derived from trees/shrubs. Applying trees shrubs continuously seems promising treating cancer.
Language: Английский
Citations
4
Royal Society of Chemistry eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 374 - 403
Published: July 19, 2024
Osteoarthritis (OA) is a major chronic and degenerative condition that affects, more frequently, the aging population. Current clinical therapies for OA can only relieve symptoms. The introduction of novel therapy regimens has been made easier by greater understanding pathophysiology OA; however, it still difficult to deliver target locations with minimal invasiveness, high retention, few adverse effects. Biocompatible injectable smart hydrogels hold great promise controlled delivery release medicines biomolecules tissue healing. In present chapter, insight provided on conventional modalities employed its treatment. Moreover, fabrication integration stimuli-responsive moieties design treatment are discussed. On other hand, succinct discussion how features composition these affect presented. Additionally presented methods utilization as cargoes various growth factors they could diverse portions injured joints in order effectively treat OA. conclusion, most recent efforts fabricate paving way further advancement refine outcomes
Language: Английский
Citations
0
Pharmaceutics, Journal Year: 2022, Volume and Issue: 14(12), P. 2827 - 2827
Published: Dec. 16, 2022
Current advances in biomaterials processing and engineering for drug delivery have allowed interesting progressed biomedical field [...]
Language: Английский
Citations
1