Antimalarial Evaluation of Magnesium Nanoparticlres of Bioactive Compounds Derived From Crinum Jagus Rhizome

Research Square (Research Square), Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 7, 2025

Magnesium Nanoparticles (MgNPs), are biocompatible and have shown promise in various biomedical applications, including antimicrobial antimalarial treatments. Synthesis of magnesium nanoparticles from crude extract isolated compound crinum jagus rhizome their activity were reported. mediated by characterized UV-visible spectroscopy, SEM TEM analyses. The absorption results the synthesized showed that varies slightly across wavelength range 343 nm to 353 nm, with a peak value 1.52934 at 345 nm. data for (lupeol) shows significant values relatively high, where absorbance is 0.88005. MgNPs exhibited best (IC50 = 0.1310), significantly outperforming both lupeol-based 0.9103) chloroquine 0.2762). enhanced extract-based may be attributed synergistic effects multiple bioactive compounds present extract. observed this study highlights potential combining traditional plant-based medicine nanotechnology. lower IC50 (0.1310) compared (0.2762) demonstrate promising future approach overcoming drug resistance improving efficacy

Language: Английский

Evaluation and toxicity of Indian plant extracts to the larvae of the malaria vector Anopheles stephensi Liston 1901 (Diptera: Culicidae)

Journal of Natural Pesticide Research, Journal Year: 2025, Volume and Issue: unknown, P. 100113 - 100113

Published: Jan. 1, 2025

Language: Английский