The Use of Neurons Derived from Pluripotent Stem Cells to Study Nerve–Cancer Cell Interactions DOI Open Access
Adriana Jiménez, Adolfo López-Ornelas,

Noelia Cruz

et al.

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(7), P. 3057 - 3057

Published: March 27, 2025

Tumor innervation is a complex interaction between nerves and cancer cells that consists of axons invading tumors, its complexity remains largely unknown in humans. Although some retrospective studies have provided important insights into the relationship further knowledge required about this biological process. Animal experiments elucidated several molecular cellular mechanisms tumor innervation; however, no experimental models currently exist to study interactions human nerve cells. Human pluripotent stem can differentiate neurons for research purposes; use these with unexplored. Hence, here we analyze potential derived from unravel poorly understood innervation.

Language: Английский

The Use of Neurons Derived from Pluripotent Stem Cells to Study Nerve–Cancer Cell Interactions DOI Open Access
Adriana Jiménez, Adolfo López-Ornelas,

Noelia Cruz

et al.

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(7), P. 3057 - 3057

Published: March 27, 2025

Tumor innervation is a complex interaction between nerves and cancer cells that consists of axons invading tumors, its complexity remains largely unknown in humans. Although some retrospective studies have provided important insights into the relationship further knowledge required about this biological process. Animal experiments elucidated several molecular cellular mechanisms tumor innervation; however, no experimental models currently exist to study interactions human nerve cells. Human pluripotent stem can differentiate neurons for research purposes; use these with unexplored. Hence, here we analyze potential derived from unravel poorly understood innervation.

Language: Английский

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