Quantification of Secondary Metabolites of Satureja pilosa (Lamiaceae) by LC-HRMS and Evaluation of Antioxidant and Cholinergic Activities DOI Open Access
Ahmet C. Gören,

Betül Kiraz Kinoğlu,

İlhami Gülçın

et al.

Records of Natural Products, Journal Year: 2024, Volume and Issue: 6, P. 674 - 686

Published: Dec. 26, 2024

In this study, secondary metabolite profiles of dichloromethane, acetone and methanol extracts leaves branches Satureja pilosa species were determined by LC-HRMS.In-vitro inhibition activities the obtained against Alzheimer's disease (AD) which is a neurodegenerative performed, structure-activity relationships discussed.While rosmarinic acid was found to be at highest rate among reported metabolites in plant, penduletin with concentration dichloromethane extract plant.The AChE leaf IC50: 41.2  5.6 μg/mL, BChE detected 52.3 8.6 μg/mL concentration.Herein, total antioxidant capacities DPPH ABTS radical scavenging CUPRAC reducing ability methods.

Language: Английский

Darutoside promotes skin wound healing via regulating macrophage polarization DOI
Liming Gao, Jing Su, Lijia Guo

et al.

Molecular Immunology, Journal Year: 2025, Volume and Issue: 181, P. 129 - 138

Published: March 26, 2025

Language: Английский

Citations

0
Polydopamine-Based Biomaterials in Orthopedic Therapeutics: Properties, Applications, and Future Perspectives DOI Creative Commons
M. Zhang,

Mi Man,

Zilong Hu

et al.

Drug Design Development and Therapy, Journal Year: 2024, Volume and Issue: Volume 18, P. 3765 - 3790

Published: Aug. 1, 2024

Polydopamine is a versatile and modifiable polymer, known for its excellent biocompatibility adhesiveness. It can also be engineered into variety of nanoparticles biomaterials drug delivery, functional modification, making it an choice to enhance the prevention treatment orthopedic diseases. Currently, application polydopamine in disease early stages, despite some initial achievements. This article aims review these applications encourage further development therapeutic needs. We detail properties biomaterial types, highlighting superior performance modification on materials. Additionally, we explore challenges future prospects developing optimal clinical use treatment.

Language: Английский

Citations

1
Comparative study of the antibacterial effects of wound secretions of different cultivars of Chinese fir DOI Creative Commons

Yu Jiang,

Yalin Zeng,

Jianing Zhu

et al.

PeerJ, Journal Year: 2024, Volume and Issue: 12, P. e17850 - e17850

Published: Aug. 16, 2024

The bark of Chinese fir (

Language: Английский

Citations

0
Differential Accumulation of Bioactive Compounds in Different Populations of Mesona chinensis Benth: An Integrated Transcriptomic and Metabolomic Analysis DOI
Yan Qin, Rui Xie, Shaozhong Peng

et al.

Food Bioscience, Journal Year: 2024, Volume and Issue: unknown, P. 105722 - 105722

Published: Dec. 1, 2024

Language: Английский

Citations

0
Quantification of Secondary Metabolites of Satureja pilosa (Lamiaceae) by LC-HRMS and Evaluation of Antioxidant and Cholinergic Activities DOI Open Access
Ahmet C. Gören,

Betül Kiraz Kinoğlu,

İlhami Gülçın

et al.

Records of Natural Products, Journal Year: 2024, Volume and Issue: 6, P. 674 - 686

Published: Dec. 26, 2024

In this study, secondary metabolite profiles of dichloromethane, acetone and methanol extracts leaves branches Satureja pilosa species were determined by LC-HRMS.In-vitro inhibition activities the obtained against Alzheimer's disease (AD) which is a neurodegenerative performed, structure-activity relationships discussed.While rosmarinic acid was found to be at highest rate among reported metabolites in plant, penduletin with concentration dichloromethane extract plant.The AChE leaf IC50: 41.2  5.6 μg/mL, BChE detected 52.3 8.6 μg/mL concentration.Herein, total antioxidant capacities DPPH ABTS radical scavenging CUPRAC reducing ability methods.

Language: Английский

Citations

0