An Innovative Approach Based on the Green Synthesis of Silver Nanoparticles Using Pomegranate Peel Extract for Antibacterial Purposes

Bioinorganic Chemistry and Applications, Journal Year: 2025, Volume and Issue: 2025(1)

Published: Jan. 1, 2025

This study describes a green synthesis method for silver nanoparticles (AgNPs) using autochthonous "Mollar de Elche" pomegranate peel extract and optimized through Python-programmed Box-Behnken design (BBD) created specifically the work. The bioactive compounds in pomegranate, particularly punicalagin, serve as effective reducing stabilizing agents. BBD was used to analyze effects of dependent variables such nitrate concentration, temperature on responses hydrodynamic diameter, polydispersity index, zeta potential, minimizing experimental trials highlighting variable interactions. Optimal conditions were experimentally validated agreed well with predicted values. AgNPs characterized via ultraviolet-visible spectrophotometry, Fourier transform infrared spectroscopy, X-ray diffraction, field emission scanning electron microscopy. These demonstrated substantial antibacterial activity against Escherichia coli Staphylococcus aureus. Furthermore, incorporated into nanofibrous scaffolds proof concept potential biomedical applications, where their partially retained postincorporation. highlights sustainable medium AgNP promising applications ability useful tool efficient optimization multivariable processes, including nanomaterials.

Language: Английский

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The effect of different wall materials on the physicochemical properties and antioxidant activity of pomegranate peel polyphenols (PPP) microcapsules

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 139958 - 139958

Published: Jan. 1, 2025

Language: Английский

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Bacterial nanocellulose and its oxidized form as functional carriers for pomegranate peel extract: A sustainable approach to bioactive delivery

Future Foods, Journal Year: 2025, Volume and Issue: unknown, P. 100560 - 100560

Published: Feb. 1, 2025

Language: Английский

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Pectin as the carrier for the spray drying of green tea extracts: Tailoring microencapsulation to obtain a prospective nutraceutical

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 141514 - 141514

Published: Feb. 1, 2025

Language: Английский

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Advancements in Cyclodextrin Complexes with Bioactive Secondary Metabolites and Their Pharmaceutical Applications

Pharmaceutics, Journal Year: 2025, Volume and Issue: 17(4), P. 506 - 506

Published: April 11, 2025

Cyclodextrins (CDs) have largely been investigated during the last decades for their outstanding properties, such as biocompatibility and biodegradability, with wide applications in pharmaceutical field, among which formation of inclusion complexes (ICs) natural or synthetic lipophilic compounds. This review prioritizes research recent years (2022–2025), being focused on (1) systematization ICs based structure secondary metabolite, namely (i) polyphenols (PPs), (ii) terpenes terpenoids (TTs), (iii) alkaloids (Alks); (2) each type complex, following aspects discussed: benefits complexation, composite materials, vitro/in vivo theoretical studies; (3) pharmacokinetics pharmacodynamics, risks, limitations, perspectives cyclodextrin metabolites.

Language: Английский

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Dietary natural products as inhibitors of α-amylase and α-glucosidase: an updated review of ligand-receptor correlations validated by docking studies

Food Bioscience, Journal Year: 2024, Volume and Issue: 62, P. 105456 - 105456

Published: Nov. 13, 2024

Language: Английский

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Endemic Plant Rumex balcanicus: Promising Source of Polyphenols with Antioxidant, Hypoglycemic and Depigmentation Potential

Chemistry & Biodiversity, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 7, 2024

Abstract Although the nutritional and health benefits of Rumex species are well known, little is known about chemical composition pharmacological activities balcanicus Rech. fil. (Polygonaceae), an endemic plant Balkan Peninsula. To best our knowledge, this paper represents first attempt to comparatively analyse phenolic composition, as in vitro activites dry hydromethanol extracts R. fruit (RBF), leaf (RBL) root (RBR), collected Serbia. The maximum total content was found RBF (386.6 mg GAE/g). characterized by high amounts miquelianin (28.8 mg/g) procyanidin B 1 (28.1 mg/g). RBL richest quercitrin (18.4 (15.0 mg/g), while nepodin (54.1 2 (40.6 were major compounds RBR. exhibited significant antioxidant activity, evaluated DPPH ( IC 50 =4.9 μg/mL), ABTS =0.8 μg/mL) FRAP (5.9 mmol Fe 2+ /g) assays. Moreover, showed strong α‐glucosidase inhibitory activity =1.8 addition notable anti‐α‐amylase, anti‐acetylcholinesterase anti‐tyrosinase activities. Molecular docking analysis predicted greatest inhibitors these enzymes. Overall, fruits stood out most promising material worth further research.

Language: Английский

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Elucidating the Microencapsulation of Bioactives from Pomegranate Fruit Waste for Enhanced Stability, Controlled Release, Biological Activity, and Application

Food and Bioprocess Technology, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 29, 2024

Language: Английский

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