Pharmaceutics,
Journal Year:
2022,
Volume and Issue:
14(10), P. 2195 - 2195
Published: Oct. 15, 2022
Liposomes
are
well-known
nanoparticles
with
a
non-toxic
nature
and
the
ability
to
incorporate
both
hydrophilic
hydrophobic
drugs
simultaneously.
As
modern
drug
delivery
formulations
produced
by
emerging
technologies,
numerous
advantages
of
liposomal
systems
over
conventional
liposomes
or
free
treatment
cancer
have
been
reported.
Recently,
liposome
nanocarriers
exhibited
high
loading
capacity,
protection,
improved
bioavailability,
enhanced
intercellular
delivery,
better
therapeutic
effect
because
resounding
success
in
targeting
delivery.
The
site
smart
responsive
liposomes,
achieved
through
changes
their
physicochemical
morphological
properties,
allows
for
controlled
release
active
compounds
under
certain
endogenous
exogenous
stimuli.
In
that
way,
multifunctional
stimuli-responsive
therapeutics
enhance
efficacy
prevention
fighting
metastases,
while
limiting
systemic
side
effects
on
healthy
tissues
organs.
Since
constitute
promising
site-targeted
anticancer
release,
this
review
focuses
recent
progress
achievements
applications.
Molecules,
Journal Year:
2022,
Volume and Issue:
27(19), P. 6280 - 6280
Published: Sept. 23, 2022
Polyphenols
(PPs)
are
a
large
group
of
phytochemicals
containing
phenolic
rings
with
two
or
more
hydroxyl
groups.
They
possess
powerful
antioxidant
properties,
multiple
therapeutic
effects,
and
possible
health
benefits
in
vivo
vitro,
as
well
reported
clinical
studies.
Considering
their
free-radical
scavenging
anti-inflammatory
these
substances
can
be
used
to
treat
different
kinds
conditions
associated
metabolic
disorders.
Many
symptoms
syndrome
(MtS),
including
obesity,
dyslipidemia,
atherosclerosis,
elevated
blood
sugar,
accelerating
aging,
liver
intoxication,
hypertension,
cancer
neurodegenerative
disorders,
substantially
relieved
by
dietary
PPs.
The
present
study
explores
the
bioprotective
properties
underlying
mechanisms
A
detailed
understanding
natural
compounds
will
open
up
new
opportunities
for
producing
unique
PP-rich
medicinal
plans,
ultimately
affirming
benefits.
International Journal of Molecular Sciences,
Journal Year:
2022,
Volume and Issue:
23(17), P. 9668 - 9668
Published: Aug. 26, 2022
Development
of
nanomaterials
for
drug
delivery
has
received
considerable
attention
due
to
their
potential
achieving
on-target
the
diseased
area
while
surrounding
healthy
tissue
is
spared.
Safe
and
efficiently
delivered
payloads
have
always
been
a
challenge
in
pharmaceutics.
Niosomes
are
self-assembled
vesicular
nanocarriers
formed
by
hydration
non-ionic
surfactant,
cholesterol
or
other
molecules
that
combine
form
versatile
system
with
variety
applications
ranging
from
topical
targeted
delivery.
advantages
similar
those
liposomes
regards
ability
incorporate
both
hydrophilic
hydrophobic
payloads.
Moreover,
niosomes
simple
manufacturing
methods,
low
production
cost
exhibit
extended
stability,
consequently
overcoming
major
drawbacks
associated
liposomes.
This
review
provides
comprehensive
summary
niosomal
research
date,
including
types
critical
material
attributes
(CMA)
process
parameters
(CPP)
effects
on
quality
(CQA)
technology.
Furthermore,
physical
characterisation
techniques
provided.
The
then
highlights
recent
specialised
Finally,
limitations
prospects
this
technology
discussed.
Applied Physics Reviews,
Journal Year:
2022,
Volume and Issue:
9(1)
Published: March 1, 2022
In
recent
years,
the
role
of
optically
sensitive
nanomaterials
has
become
powerful
moieties
in
therapeutic
techniques
and
particularly
emphasized.
Currently,
by
extraordinary
development
different
fields
medicine,
they
have
found
new
applications.
Phototherapy
modalities,
such
as
photothermal
therapy
(PTT)
toxic
heat
generation
photodynamic
(PDT)
reactive
oxygen
species,
are
known
promising
phototherapeutic
techniques,
which
can
overcome
limitations
conventional
protocols.
Moreover,
nanomaterial-based
PDT
PTT
match
simultaneous
immune
increase
system
stimulation
resulting
from
denaturation
cancer
cells.
Nevertheless,
should
sufficient
biocompatibility
efficiency
to
meet
requirements
agents.
The
present
review
focuses
on
potency
PDT,
PTT,
also
their
combined
alternative
protocols
with
minimal
morbidity
integrated
into
gold
standard
treatments
surgery,
chemotherapy,
radiation
at
tumor
treatment
cancer-related
infectious
diseases.
addition,
for
deeper
understanding,
photoablation
effects
emphasis
nature,
morphology,
size
photosensitive
were
studied.
Finally,
transportation
needed
carriers
photosensitizers
agents
hard-accessed
regions,
example,
cancerous
investigated.
Pharmaceutics,
Journal Year:
2022,
Volume and Issue:
14(10), P. 2195 - 2195
Published: Oct. 15, 2022
Liposomes
are
well-known
nanoparticles
with
a
non-toxic
nature
and
the
ability
to
incorporate
both
hydrophilic
hydrophobic
drugs
simultaneously.
As
modern
drug
delivery
formulations
produced
by
emerging
technologies,
numerous
advantages
of
liposomal
systems
over
conventional
liposomes
or
free
treatment
cancer
have
been
reported.
Recently,
liposome
nanocarriers
exhibited
high
loading
capacity,
protection,
improved
bioavailability,
enhanced
intercellular
delivery,
better
therapeutic
effect
because
resounding
success
in
targeting
delivery.
The
site
smart
responsive
liposomes,
achieved
through
changes
their
physicochemical
morphological
properties,
allows
for
controlled
release
active
compounds
under
certain
endogenous
exogenous
stimuli.
In
that
way,
multifunctional
stimuli-responsive
therapeutics
enhance
efficacy
prevention
fighting
metastases,
while
limiting
systemic
side
effects
on
healthy
tissues
organs.
Since
constitute
promising
site-targeted
anticancer
release,
this
review
focuses
recent
progress
achievements
applications.
