Point-of-care diagnostics for sepsis using clinical biomarkers and microfluidic technology

Biosensors and Bioelectronics, Journal Year: 2023, Volume and Issue: 227, P. 115181 - 115181

Published: Feb. 24, 2023

Sepsis is a life-threatening immune response which caused by wide variety of sources and leading cause mortality globally. Rapid diagnosis appropriate antibiotic treatment are critical for successful patient outcomes; however, current molecular diagnostic techniques time-consuming, costly require trained personnel. Additionally, there lack rapid point-of-care (POC) devices available sepsis detection despite the urgent requirements in emergency departments low-resource areas. Recent advances have been made toward developing POC test early that will be more accurate compared to conventional techniques. Within this context, review discusses use novel biomarkers using microfluidics testing.

Language: Английский

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Highly flexible, PEDOT:PSS-polyvinylpyrrolidone coated carbon nanofiber-polydimethylsiloxane composite for electromagnetic interference shielding

Synthetic Metals, Journal Year: 2023, Volume and Issue: 296, P. 117376 - 117376

Published: May 19, 2023

Language: Английский

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Recent progress in structural design of graphene/polymer porous composites toward electromagnetic interference shielding application

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 495, P. 153586 - 153586

Published: June 28, 2024

Language: Английский

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The impact of nanoparticle leach on sustainable performance of the membranes – A critical review

Environmental Nanotechnology Monitoring & Management, Journal Year: 2024, Volume and Issue: 22, P. 100984 - 100984

Published: July 16, 2024

Fouling remains a major challenge in membrane-based water treatment technologies. As result, contemporary research is geared towards membrane surface modification techniques to reduce fouling. Mitigation strategies involving incorporation of nanoparticles (NPs) into polymeric membranes has gained remarkable interest. However, NPs leach eminent, particularly with poor support on resulting secondary pollution. Consequently, aquatic life threatened depending the level toxicity leached NPS. Also, these present toxicological effects other consumers. Therefore, this work reviews literature paying attention polymer matrices. Various factors governing are concisely presented. Special was focused stability immobilization due thermodynamic interactions. Similarly, physicochemical properties and NPS ecotoxicity discussed detail based reports. Different approaches presenting improvement NP matrix discussed. Lastly casting future perspectives impact sustainable performance

Language: Английский

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Wearable Devices for Respiratory Monitoring

Advanced Functional Materials, Journal Year: 2024, Volume and Issue: unknown

Published: June 10, 2024

Abstract Respiratory diseases are currently monitored through traditional pulmonary function tests, such as spirometry. However, the restrictions of these procedures, particularly in context COVID‐19 pandemic, have underscored need for alternative approaches to respiratory health assessment. Wearable devices emerged a promising solution, providing continuous data collection, and overcoming limitations posed by conventional methods. This review explores multifaceted field wearable monitoring, presenting most common sensing technologies applied ventilation, their constituent materials, fabrication techniques, diverse morphologies enhance sensor performance. The role machine learning algorithms ethical sharing is highlighted, contributing forthcoming patient‐centered healthcare landscape. Ultimately, importance validation calibration protocols underlined. In anticipation evolving needs, this in‐depth study addresses current challenges monitoring while laying robust foundation personalized, connected, ethically sound future care.

Language: Английский

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Bio‐Disintegrable Elastic Polymers for Stretchable Piezoresistive Strain Sensors

Advanced Sustainable Systems, Journal Year: 2024, Volume and Issue: 8(6)

Published: Jan. 9, 2024

Abstract The fast‐growing usage of electronics is creating large amounts e‐waste (electronic waste), most which are directly sent into landfills or incinerated as recycling either impractical too costly. Therefore, it believed that degradable, environmentally friendly materials the solution to this pressing issue. Herein, disintegrable, durable, and highly stretchable strain sensors developed based on elastic thin films made sodium carboxymethyl cellulose, glycerol, polyvinyl alcohol. polymer show a failure up ≈ 330% low hysteresis (5.74% at second cycle) when subjected 50% cyclic strain, due formation inter intramolecular hydrogen bonds. Carbon nanofibers with Au film deposited film, resulting in piezoresistive maximum gauge factor 1.7. More interestingly, as‐developed can be completely broken down hot water (at 95 °C) within 25 min, indicating their remarkable disintegrability. This unique characteristic expected contribute environmental sustainability. applications sensor for joint bending recognition well physiological sign measurement have been demonstrated.

Language: Английский

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Sustainable Soft Electronics Combining Recyclable Metal Nanowire Circuits and Biodegradable Gel Film Substrates

Advanced Electronic Materials, Journal Year: 2024, Volume and Issue: 10(6)

Published: Jan. 15, 2024

Abstract Direct disposal of used soft electronics into the environment can cause severe pollution to ecosystem due inability most inorganic materials and synthetic polymers biodegrade. Additionally, loss noble metals that are commonly in leads a waste scarce resources. Thus, there is an urgent need develop “green” sustainable based on eco‐friendly manufacturing may be recycled or biodegraded after devices’ end life. Here approach fabricating demonstrated where expensive functional substrate biodegradable. A stretchable agarose/glycerol gel film as substrate, silver nanowires (AgNWs) printed fabricate electronic circuits. The mechanical chemical properties films characterized, functionality AgNW electrodes for electrophysiological sensors demonstrated. demonstration biodegradability recyclability AgNWs points toward ways electronics.

Language: Английский

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Measurement of Axial and Shear Mechanical Response of PDMS Elastomers and Determination of Poisson’s Ratio using Digital Image Correlation

Polymer Testing, Journal Year: 2025, Volume and Issue: unknown, P. 108687 - 108687

Published: Jan. 1, 2025

Language: Английский

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Biomechanics in the tumor microenvironment: from biological functions to potential clinical applications

Experimental Hematology and Oncology, Journal Year: 2025, Volume and Issue: 14(1)

Published: Jan. 11, 2025

Abstract Immune checkpoint therapies have spearheaded drug innovation over the last decade, propelling cancer treatments toward a new era of precision therapies. Nonetheless, challenges low response rates and prevalent resistance underscore imperative for deeper understanding tumor microenvironment (TME) pursuit novel targets. Recent findings revealed profound impacts biomechanical forces within on immune surveillance progression in both murine models clinical settings. Furthermore, pharmacological or genetic manipulation mechanical checkpoints, such as PIEZO1, DDR1, YAP/TAZ, TRPV4, has shown remarkable potential activation eradication tumors. In this review, we delved into underlying mechanisms resulting intricate biological meaning TME, focusing mainly extracellular matrix, stiffness cells, synapses. We also summarized methodologies employed research translation derived from current evidence. This comprehensive review biomechanics will enhance functional role provide basic knowledge discovery therapeutic

Language: Английский

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Poly(lactic acid)-based materials with enhanced gas permeability for modified atmosphere packaging of Chinese bayberry

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 140202 - 140202

Published: Jan. 1, 2025

Language: Английский

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