Application of Hydroxyapatite Composites in Bone Tissue Engineering: A Review

Journal of Functional Biomaterials, Journal Year: 2025, Volume and Issue: 16(4), P. 127 - 127

Published: April 2, 2025

The treatment of bone defects is complicated by clinical conditions, such as trauma, tumor resection, and infection, which result in impair the bone’s regenerative capacity. Hydroxyapatite (HAp), primary inorganic component bone, possesses good biocompatibility osteoconductivity. However, it has poor mechanical properties, a slow degradation rate, limited functionality, necessitating combination with other materials to broaden its application scope. This paper summarizes importance properties HAp composites provides categorized review current research on tissue engineering. These composite scaffolds not only offer excellent support for cell growth regeneration but also facilitate new formation vascularization. Additionally, challenges faced composites, material property optimization improvement preparation techniques, are discussed. applications defect repair, dental implants, spinal fusion, fields.

Language: Английский

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Tissue Engineering Strategies Applied in Bone Regeneration and Bone Repair

Bioengineering, Journal Year: 2023, Volume and Issue: 10(6), P. 644 - 644

Published: May 25, 2023

Bone regeneration and repair present significant challenges in the field of regenerative medicine [...].

Language: Английский

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Porcine thigh as an ideal cadaveric animal model for flap training: a home do-it-yourself model

European Journal of Plastic Surgery, Journal Year: 2024, Volume and Issue: 47(1)

Published: July 11, 2024

Language: Английский

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Bioabsorbable Composites Based on Polymeric Matrix (PLA and PCL) Reinforced with Magnesium (Mg) for Use in Bone Regeneration Therapy: Physicochemical Properties and Biological Evaluation

Polymers, Journal Year: 2023, Volume and Issue: 15(24), P. 4667 - 4667

Published: Dec. 11, 2023

Improvements in Tissue Engineering and Regenerative Medicine (TERM)-type technologies have allowed the development of specific materials that, together with a better understanding bone tissue structure, provided new pathways to obtain biomaterials for regeneration. In this manuscript, bioabsorbable are presented as emerging engineering therapies related lesions because their ability degrade physiological environments while regeneration process is completed. This comprehensive review aims explore studies, published since its inception (2010s) present, on composite based PLA PCL polymeric matrix reinforced Mg, which also has recognized osteoinductive capacity. The research collected literature reveals studies different manufacturing dispersion processes reinforcement well physicochemical analysis corresponding biological evaluation know capacity proposed PLA/Mg PCL/Mg composites. short, shows potential these serves guide those interested applied engineering.

Language: Английский

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Trends in bioactivity: inducing and detecting mineralization of regenerative polymeric scaffolds

Journal of Materials Chemistry B, Journal Year: 2024, Volume and Issue: 12(11), P. 2720 - 2736

Published: Jan. 1, 2024

Advances in bioactive regenerative polymeric scaffolds continue to be made with new materials and methods of characterization.

Language: Английский

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