Modern
techniques
of
thin
film
deposition
(e.g.,
atomic
layer
(ALD))
have
paved
the
way
for
modification
surface
target
substrates
with
films,
nanoparticles,
or
other
types
nanomaterials.
This
novel
can
improve
properties
base
material
and
has
capability
to
add/enhance
specific
through
addition
functionalized
groups
surface.In
this
study,
ALD
silver
was
carried
out
on
commercially
available
collagen
membrane
bioactivity.
Two
different
sample
were
studied:
pristine
silver-coated
via
(Ag/Collagen).
Chemical
morphological
changes
investigated
X-ray
photoelectron
spectroscopy
scanning
electron
microscopy
bioactivity
studied
in
vivo.Nano-islands
obtained
fibrils
an
average
diameter
~16
nm.
Comparison
gingival
cells
cultured
collagen,
demonstrated
that
attained
nanoparticle
size
concentration
are
below
toxicity
level
oral
environment.
In
vivo
assessment
showed
biocompatibility
Collagen-1300Ag,
greater
new
bone
formation.
be
used
surgeries
as
grafting
agent
osteopromotive
properties.
Gels,
Journal Year:
2023,
Volume and Issue:
9(4), P. 277 - 277
Published: March 27, 2023
Chitosan
is
a
promising
naturally
derived
polysaccharide
to
be
used
in
hydrogel
forms
for
pharmaceutical
and
biomedical
applications.
The
multifunctional
chitosan-based
hydrogels
have
attractive
properties
such
as
the
ability
encapsulate,
carry,
release
drug,
biocompatibility,
biodegradability,
non-immunogenicity.
In
this
review,
advanced
functions
of
are
summarized,
with
emphasis
on
fabrications
resultant
reported
literature
from
recent
decade.
progress
applications
drug
delivery,
tissue
engineering,
disease
treatments,
biosensors
reviewed.
Current
challenges
future
development
direction
prospected.
International Journal of Molecular Sciences,
Journal Year:
2025,
Volume and Issue:
26(2), P. 764 - 764
Published: Jan. 17, 2025
Marine
polysaccharide
hydrogels
have
emerged
as
an
innovative
platform
for
regulating
the
in
vivo
release
of
natural
bioactive
compounds
medical
purposes.
These
hydrogels,
which
exceptional
biocompatibility,
biodegradability,
and
high
water
absorption
capacity,
create
effective
matrices
encapsulating
different
molecules.
In
addition,
by
modifying
physical
chemical
properties
marine
including
cross-linking
density,
swelling
behavior,
response
to
external
stimuli
like
pH,
temperature,
or
ionic
strength,
profile
encapsulated
is
strictly
regulated,
thus
maximizing
therapeutic
efficacy
minimizing
side
effects.
Finally,
using
naturally
sourced
polysaccharides
hydrogel
formulations,
sustainability
promoted
reducing
dependence
on
synthetic
polymers,
meeting
growing
demand
eco-friendly
materials.
This
review
analyzes
interaction
between
offers
examples
how
molecules
can
be
encapsulated,
released,
stabilized.
ACS Biomaterials Science & Engineering,
Journal Year:
2023,
Volume and Issue:
9(6), P. 3084 - 3115
Published: May 13, 2023
Over
the
past
decade,
smart
and
functional
biomaterials
have
escalated
as
one
of
most
rapidly
emerging
fields
in
life
sciences
because
performance
could
be
improved
by
careful
consideration
their
interaction
response
with
living
systems.
Thus,
chitosan
play
a
crucial
role
this
frontier
field
it
possesses
many
beneficial
properties,
especially
biomedical
such
excellent
biodegradability,
hemostatic
antibacterial
activity,
antioxidant
biocompatibility,
low
toxicity.
Furthermore,
is
versatile
biopolymer
due
to
its
polycationic
nature
reactive
groups
that
allow
polymer
form
interesting
structures
or
modified
various
ways
suit
targeted
applications.
In
review,
we
provide
an
up-to-date
development
chitosan-based
nanoparticles,
hydrogels,
nanofibers,
films,
well
application
field.
This
review
also
highlights
several
strategies
enhance
biomaterial
for
fast
growing
applications
drug
delivery
systems,
bone
scaffolds,
wound
healing,
dentistry.
Frontiers in Bioengineering and Biotechnology,
Journal Year:
2024,
Volume and Issue:
12
Published: June 26, 2024
Introduction:
The
production
of
bone-like
structural
scaffolds
through
bone
tissue
engineering
technology
is
a
promising
method
for
regeneration
to
repair
defects.
Deer
antler,
an
easily
harvested
and
abundantly
sourced
initial
structure,
resembles
the
composition
structure
human
cancellous
can
serve
as
new
material
allogeneic
transplantation.
Methods:
This
study
involved
preparation
characterization
antler
powder/chitosan/β-glycerophosphate
sodium/polyvinyl
alcohol
(AP/CS/β-GP/PVA)
porous
hydrogel
verify
their
properties
osteogenic
mechanisms.
microstructure,
hydrophilicity,
mechanical
were
studied
using
Scanning
Electron
Microscopy
(SEM),
contact
angle
measurement,
universal
testing
machine.
interactions
between
various
components
investigated
Fourier-Transform
Infrared
Spectroscopy
(FTIR).
Biocompatibility,
properties,
expression
osteogenesis-related
proteins
evaluated
Cell
Counting
Kit-8
(CCK-8)
assays,
alkaline
phosphatase
staining,
Alizarin
Red
live/dead
cell
Western
blot
analysis.
Results:
results
showed
that
content
deer
powder
increased,
both
hydrophilicity
scaffold
materials
improved,
while
porosity
slightly
decreased
with
increase
in
content.
culture
experiments
demonstrated
higher
proportion
beneficial
proliferation
differentiation
mouse
pre-osteoblast
(MC3T3-E1)
cells,
containing
10%
8%
showing
best
effects.
upregulation
RUNX2,
OCN,
OSX,
OPN
protein
may
promote
differentiation.
Discussion:
Therefore,
AP/CS/β-GP/PVA
have
potential
become
biomaterial
engineering.
Heliyon,
Journal Year:
2025,
Volume and Issue:
11(3), P. e42177 - e42177
Published: Jan. 23, 2025
Modern
techniques
of
thin
film
deposition
(e.g.,
atomic
layer
[ALD])
have
paved
the
way
for
modification
surface
target
substrates
with
films,
nanoparticles,
or
other
types
nanomaterials.
This
novel
can
improve
base
material's
properties
and
enhance
specific
through
adding
functionalized
groups
to
surface.
In
this
study,
ALD
silver
was
conducted
on
commercially
available
Type
I
collagen
membrane
its
bioactivity
promote
bone
healing.
Two
different
sample
were
studied:
pristine
silver-coated
via
(Ag/Collagen).
Chemical
morphological
changes
investigated
X-ray
photoelectron
spectroscopy
scanning
electron
microscopy
studied
in
vitro
vivo.
Nano-islands
obtained
fibrils
an
average
diameter
∼16
nm.
Comparison
gingival
cells
cultured
collagen,
demonstrated
that
attained
nanoparticle
size
concentration
are
below
toxicity
level
silver.
vivo
assessment
rat
model
showed
biocompatibility
Ag/Collagen,
greater
new
formation
compared
control.
solvent-free
method
be
used
functionalize
sensitive
materials
surgeries
as
grafting
agents
osteopromotive
without
any
adverse
effects
cellular
environment.
Pharmaceutics,
Journal Year:
2025,
Volume and Issue:
17(2), P. 249 - 249
Published: Feb. 14, 2025
Gels
constitute
a
versatile
class
of
materials
with
considerable
potential
for
applications
in
both
technical
and
medical
domains.
Physicochemical
property
characterization
is
critical
evaluation
method
gels.
Common
techniques
include
pH
measurement,
structural
analysis,
mechanical
assessment,
rheological
phase
transition
studies,
among
others.
While
numerous
research
articles
report
results,
few
reviews
comprehensively
summarize
the
appropriate
numerical
ranges
these
properties.
This
lack
standardization
complicates
harmonized
methods
hinders
direct
comparisons
between
different
To
address
this
gap,
it
essential
to
systematically
investigate
analyze
data
from
extensive
body
literature
on
In
review,
we
provide
comprehensive
summary
general
present
detailed
analysis
gel
support
future
promote
standardized
protocols.
Gels,
Journal Year:
2025,
Volume and Issue:
11(3), P. 175 - 175
Published: Feb. 27, 2025
Bone
tissue
engineering
has
emerged
as
a
promising
approach
to
addressing
the
limitations
of
traditional
bone
grafts
for
repairing
defects.
This
regenerative
medicine
strategy
leverages
biomaterials,
growth
factors,
and
cells
create
favorable
environment
regeneration,
mimicking
body’s
natural
healing
process.
Among
various
biomaterials
explored,
hydrogels
(HGs),
class
three-dimensional,
hydrophilic
polymer
networks,
have
gained
significant
attention
scaffolds
engineering.
Thus,
this
review
aimed
investigate
potential
synthetic
HGs,
molecules
used
its
functionalization,
enhanced
applications.
HGs
offer
several
advantages
such
scaffolds,
including
biocompatibility,
biodegradability,
tunable
mechanical
properties,
ability
encapsulate
deliver
bioactive
molecules.
These
properties
make
them
ideal
candidates
supporting
cell
attachment,
proliferation,
differentiation,
ultimately
guiding
formation
new
tissue.
The
design
optimization
HG-based
involve
adapting
their
composition,
structure,
meet
specific
requirements
regeneration.
Current
research
focuses
on
incorporating
molecules,
factors
cytokines,
into
HG
further
enhance
osteoinductive
osteoconductive
properties.
Additionally,
strategies
improve
strength
degradation
kinetics
are
being
explored
ensure
long-term
stability
support
formation.
development
advanced
holds
great
revolutionizing
providing
effective
treatment
options
patients
with