Polymethyl Methacrylate Bone Cement Polymerization Induced Thermal Necrosis at the Cement–Bone Interface: A Narrative Review DOI Creative Commons

Gergo Tamas Szoradi,

Andrei Marian Feier, Sándor-György Zuh

et al.

Applied Sciences, Journal Year: 2024, Volume and Issue: 14(24), P. 11651 - 11651

Published: Dec. 13, 2024

Polymethyl methacrylate (PMMA) bone cement has been a transformative material in orthopedics since its introduction the mid-20th century. Originally used dental medicine, PMMA was adopted for orthopedic applications by Sir John Charnley 1950s, significantly enhancing joint replacement surgeries. The primary appeal of lies biocompatibility, mechanical strength, and ease handling, making it favored choice various procedures, including arthroplasties limb-salvage However, exothermic polymerization process poses risk thermal necrosis surrounding tissue, as local temperatures can exceed 70 °C, causing damage to osteocytes. Research sought mitigate these risks optimizing mixing techniques, reducing mantle thickness, incorporating cooling methods. Recent advancements, such use phase-change materials (PCMs) alternative monomers, have shown promise lowering peak during polymerization. Other strategies include pre-cooling prosthetic components using composite cement. Despite innovations, managing balance between minimizing heat generation maintaining properties remains challenge. impact is significant, compromising implant stability osseointegration. Understanding complex interactions PMMA’s clinical outcomes essential improving surgical practices patient recovery.

Language: Английский

Latest advancements and trends in biomedical polymers for disease prevention, diagnosis, treatment, and clinical application DOI

Mingxia Jiang,

Huapan Fang,

Huayu Tian

et al.

Journal of Controlled Release, Journal Year: 2025, Volume and Issue: 380, P. 138 - 174

Published: Feb. 5, 2025

Language: Английский

Citations

2
An updated review on the modifications, recycling, polymerization, and applications of polymethyl methacrylate (PMMA) DOI
Great Iruoghene Edo, Winifred Ndudi,

Ali B. M. Ali

et al.

Journal of Materials Science, Journal Year: 2024, Volume and Issue: 59(44), P. 20496 - 20539

Published: Nov. 1, 2024

Language: Английский

Citations

12
Improving damping properties of cement mortar using oxidized and methyl methacrylate-grafted coconut fibers DOI
Xiaocong Yang, Dongyang Tian, Zhicheng Gao

et al.

Construction and Building Materials, Journal Year: 2025, Volume and Issue: 461, P. 139957 - 139957

Published: Jan. 1, 2025

Language: Английский

Citations

1
Tuning the Optical Properties of Electrospun Poly(methyl methacrylate) Nanofibres via Montmorillonite and Magnetite Ratios DOI Open Access
Yao Mawuena Tsekpo, Weronika Smok, Krzysztof Matus

et al.

Polymers, Journal Year: 2025, Volume and Issue: 17(3), P. 384 - 384

Published: Jan. 31, 2025

Poly(methyl methacrylate) (PMMA) polymer has unlocked new frontiers in the field of nanotechnology and is suitable for a wide range applications. However, its optical band gap limits use optoelectronics. This study aims to ascertain influence varying montmorillonite magnetite ratios on properties electrospun PMMA nanofibres produced from solution. The were characterised using Fourier-transform infrared spectroscopy (FTIR), atomic force microscopy (AFM), scanning electron (SEM), X-ray diffractometry (XRD), energy-dispersive (EDX), spectroscopic ellipsometry, UV-Vis (UV-Vis). XRD analysis revealed successful incorporation within matrix, with diameters ranging 203 328 nm. altered light absorption characteristics PMMA, resulting increased ultraviolet visible regions compared pristine reduction 4.9 eV 2.5 eV. These findings suggest that host matrix magnetite. observed also indicate suitability materials optoelectronic applications, including chemical sensors protective UV coatings.

Language: Английский

Citations

0
Poly(oligoethylene glycol methylether methacrylate-co-methyl methacrylate) Aggregates as Nanocarriers for Curcumin and Quercetin DOI Open Access

Michaila Akathi Pantelaiou,

Dimitrios Vagenas,

Stergios Pispas

et al.

Polymers, Journal Year: 2025, Volume and Issue: 17(5), P. 635 - 635

Published: Feb. 27, 2025

Amphiphilic statistical copolymers can be utilized for the formulation of nanocarriers drug delivery insoluble substances. Oligoethylene glycol methylether methacrylate and methyl are two biocompatible monomers that used biological applications. In this work, synthesis linear poly(oligoethylene methacrylate-co-methyl methacrylate), P(OEGMA-co-MMA), via reversible addition fragmentation chain transfer (RAFT) polymerization is reported. P(OEGMA-co-MMA) with different comonomer compositions were synthesized characterized by size exclusion chromatography (SEC), 1H-NMR, ATR-FTIR spectroscopy. Self-assembly studies carried out dissolution polymers in water co-solvent protocol. For characterization formed nanoaggregates, DLS, zeta potential, fluorescence spectroscopy (FS) experiments performed. Such measurements delineate association into aggregates structural characteristics dependent on copolymer composition. order to investigate encapsulation properties nanoparticles, curcumin quercetin loaded them. The protocol was followed varying concentrations drugs. Nanocarrier confirmed DLS while UV-Vis FS revealed loading optical drug-loaded nanosystems each case. maximum efficiency found 54% 49% quercetin. all nanocarriers, preliminary qualitive biocompatibility conducted FBS medium aqueous solutions which resulted no significant interactions between serum proteins. Novel fabricated as a first step utilization these nanomedicine.

Language: Английский

Citations

0
Experimental Study of a Novel Semi-Transparent Bi-Facial Agri-Voltaic System: Initial Results DOI Creative Commons
Duncan McGraw,

Tonny Nyonga,

Laura Green

et al.

Deleted Journal, Journal Year: 2025, Volume and Issue: 3

Published: March 3, 2025

Solar (photovoltaic)-agriculture practices have experienced notable progress across several countries over the past few decades, creating a field widely known as agrivoltaics. This co-location practice has proved effective for certain crops that prefer partial shade like tomatoes, lettuce, and peppers, although it is less needing more sun. Availability of natural sunlight with specific spectral signature necessary agricultural many plant species require an optimum-level quality photosynthesis. The goal this work to model validate ground-level irradiance semi-transparent bifacial solar collector equipped custom reflector. By introducing intentional gaps between opaque cells, we hope allow 50% visible light pass through module. Additionally, technology could reduce soil temperature by 2° C, improve moisture retention, enhance yield providing radiation. In our model, can calculate total plants function cell distribution, material absorption, height panel time year spatial resolution 0.0625 m2. When comparing theoretical estimates experimental measurements photosynthetically active radiation (PAR), find discrepancy 32-48%, 19-38% after correction TMY data.

Language: Английский

Citations

0
Comparison of physico-chemical properties of different types of orthopedic acrylic cement DOI

Elnaz Taghizadeh,

Mona Navaei‐Nigjeh, Masoud Mirkazemi

et al.

Journal of Biomaterials Science Polymer Edition, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 21

Published: Jan. 15, 2025

Analyzing the chemical composition of different kinds acrylic cement is necessary to understand their properties and suitability for curing bone defects. Conducting various tests can give valuable insight into composition, viscosity, performance characteristics each kind cement, Therefore, our study aimed find safety standards effectiveness these products medical applications. The polymeric characterization was determined by Nuclear Magnetic Resonance (H-NMR) spectroscopy Fourier-transform infrared (FTIR). Additionally, gel permeation chromatography (GPC) used determine molecular weight poly methyl methacrylate (PMMA), which between 4000 6000 Mw. presence (MMA) monomer observed in all within two minutes using gas chromatography-mass spectrometry (GC-MS). Moreover, images radiopaque compounds were evaluated Field emission scanning electron microscopy (FESEM) Energy Dispersive X-ray (EDAX-MAP). glass transition (Tg) temperature conducted differential calorimetry (DCS) analysis type cement. In addition, setting time spinal cord measured be more than ten minutes. percentage benzoyl peroxide titration, ranging from 0.6% 6%. cytotoxicity studies on human osteoblasts (MG63) cell culture. this study, we tried make a trend line evaluation types that would applicable both regulatory buddies researchers field.

Language: Английский

Citations

0
Antibacterial Properties of PMMA/ZnO(NanoAg) Coatings for Dental Implant Abutments DOI Open Access

Ana Maria Gianina Rehner,

Dana-Ionela Tudorache,

Alexandra Cătălina Bîrcă

et al.

Materials, Journal Year: 2025, Volume and Issue: 18(2), P. 382 - 382

Published: Jan. 15, 2025

Infections continue to pose significant challenges in dentistry, necessitating the development of innovative solutions that can effectively address these issues. This study focuses on creating coatings made from polymethyl methacrylate (PMMA) enriched with zinc oxide-silver composite nanoparticles, layered Ti6Al4V-titanium alloy substrates. The application materials aims create a solution for abutments utilized complete dental implant systems, representing area most susceptible bacterial infections. nanoparticles were synthesized using hydrothermal method, optimized through specific temperature and pressure parameters achieve effective morphologies sizes enhance antibacterial efficacy. layers applied titanium substrate spin coating technique, chosen its advantages compatibility involved. Comprehensive analyses conducted antimicrobial powders, including X-ray diffraction, Fourier transform infrared spectroscopy, scanning electron microscopy, energy-dispersive spectroscopy. Furthermore, PMMA-based incorporating evaluated ensure uniformity homogeneity across surface by IR mapping SBF immersion-SEM analysis. activity samples was demonstrated impressive results against Staphylococcus aureus, Pseudomonas aeruginosa, Candida albicans, as assessed biofilm modulation studies. biocompatibility validated vitro cell-based assays, which excellent between human preosteoblasts, confirming their potential suitability future use implants.

Language: Английский

Citations

0
Local antibiotic delivery: Recent basic and translational science insights in orthopedics DOI
Amir Human Hoveidaei, Seyedarad Mosalamiaghili,

Amirhosein Sabaghian

et al.

Bone, Journal Year: 2025, Volume and Issue: unknown, P. 117416 - 117416

Published: Feb. 1, 2025

Language: Английский

Citations

0
Inverse determination of the thermal contact conductance for an interface between a Co28Cr6Mo hip stem and a PMMA-based bone cement DOI Creative Commons

Patrick Evers,

Magnus Reulbach, Crystal Kayaro Emonde

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Feb. 13, 2025

Abstract Traditional mechanical methods for implant and bone cement removal during total hip arthroplasty (THA) revision surgeries typically lead to surrounding tissue damage increased risk of femoral fractures. Transcutaneous induction heating is a promising new approach as it causes softening the thermoplastic cement, thus prevents increases stability post-revision. However, precise knowledge heat transfer between necessary minimize thermal tissues. In this context, contact conductance (TCC) at interface Co28Cr6Mo stems PMMA-based key issue. The present study addresses challenge measuring TCC by proposing an inverse method determination using infrared thermography measurements process finite element simulation with variable parameter TCC. Results indicate values 3,125 ± 275 Wm − 2 K 1 dry interfaces 5,100 300 wet interfaces. influence conduction on surface temperature significant, impacting measured temperatures 15–19% 23–30% These findings are crucial design procedures minimization assisted THA revisions.

Language: Английский

Citations

0