Synthesis and characterization of new electrospun medical scaffold-based modified cellulose nanofiber and bioactive natural propolis for potential wound dressing applications

RSC Advances, Journal Year: 2024, Volume and Issue: 14(36), P. 26183 - 26197

Published: Jan. 1, 2024

Recently, the design of polymer nanofibers using electrospinning process has attracted much interest. Particularly use natural polymers promoted many advantages in their biomedical applications. However, combination multiple remains a great challenge terms electrospun production and applied performance. From this perspective, current investigation highlights study preparation nanomaterial scaffolds based on combined for improved wound healing First, we have synthesized crosslinked by reacting microcrystalline cellulose (MC) chitosan (CS) biopolymer

Language: Английский

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Potential of Natural Plant-Based Materials in the Development of Biocompatible Drug-Eluting Surgical Sutures: A Review

Deleted Journal, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 5, 2024

Sutures are maneuvered in surgery for wound closure procedure with the aim of healing after injury or discretionary interventions hemostasis articulation. In spite renaissance advancement sutures, natural fibers like silk and catgut chromium threads still used surgical modified version terms biocompatibility, antimicrobial properties, drug-eluting characteristics. Natural plant biomaterials have lots opportunities to act as sutures potential prevent inflammatory responses, increased collagen synthesis, helping overall tissue reconstruction. Further, materials more advantageous than synthetic high biodegradability, reduced antigenicity, renewability. The present investigation addresses number plants their parts, demonstrating suture material, such Boehmeria nivea, Tinospora cordifolia, Moringa oleifera, Curcuma longa, Lawsonia inermis, Aloe vera, Azadirachta indica, Nepeta dschuparensis B., Chamomile plant, Cocos nucifera L., Trigonella foenum-graecum, Linum usitatissimum, Commelina benghalensis, Syzygium cumini. Instead, there numerous which unexplored but possess suturing material Though, continuous furtherance development is not a perfect universal affordable right every patient. Thus by combining core characteristics advanced technology, it might be possible develop ideal plant-based materials. This review focuses on biocompatible suture, while digging deep into how phyto-constituents can serve advance this field.

Language: Английский

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Antimicrobial polymers: elucidating the role of functional groups on antimicrobial activity

Arab Journal of Basic and Applied Sciences, Journal Year: 2024, Volume and Issue: 31(1), P. 325 - 344

Published: June 18, 2024

The swift increase in antimicrobial resistance across the world presents a significant challenge, further raised by insufficient advancement design of new agents. Over past two decades, variety sources has been investigated for generating antimicrobials. Recently, polymers (APs) have emerged as multifaceted agents, displaying effectiveness against range pathogens such bacteria, fungi, and viruses. Their notable biocompatibility, efficiency, multifunctionality, ease modification make them focal point research. APs are particularly valued their structural versatility, which allows integration functional groups. Polymer functionalization does not only enhance or introduce properties but also maintains high levels biocompatibility. This review reveals broad breadth APs, can be potentially used antiseptics, food packaging, biomedical sector, e.g. medical implants' coatings. In laboratory settings, shown promising therapeutic effects, however there remains an urgent need computational biology to fully understand behaviour stability. Recombinant biotechnological approaches essential facilitating production require industrial collaboration effectively optimize scale up these processes.

Language: Английский

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Production and Characterization of Electrospun Chitosan, Nanochitosan and Hyaluronic Acid Membranes for Skin Wound Healing

Journal of Biomedical Materials Research Part B Applied Biomaterials, Journal Year: 2024, Volume and Issue: 112(10)

Published: Sept. 26, 2024

ABSTRACT The development of new wound dressings made from biomaterials, which offer a better cost–benefit ratio and accelerate the healing process, is increasing nowadays. Various biopolymers can be electrospun to form functional membranes for healing. Therefore, in this study, chitosan nanochitosan with or without hyaluronic acid were prepared using electrospinning technique, characterized evaluated skin wounds rats. Chitosan solutions, acid, at concentrations 1%–4% PEO (polyethylene oxide) subjected process obtain by scanning electron microscopy (SEM), mechanical tests, antimicrobial activity. effect was monitoring area lesions, contraction wounds, histologic analysis, induction pro‐inflammatory cytokine (IL‐1 α TNF‐α) production achieved greater fiber diameter uniformity, resistance, elasticity, thermal stability, addition good adhesion bed permeation capacity. Despite not presenting activity vitro, they contributed interleukins animals tested, provided physical protection, reduced more markedly until seventh day evaluation, an acceleration especially when functionalized acid. These results indicate that may promising accelerating chronic humans.

Language: Английский

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From waste to Innovation: Advancing the circular economy with nanofibers using recycled polymers and natural polymers from renewable or waste residues

Journal of Industrial and Engineering Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 1, 2024

Language: Английский

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