Review: Biomacromolecules‐based encapsulation technologies for the protection of oxygen‐sensitive next‐generation probiotics DOI Creative Commons
Thị‐Thanh‐Trúc Phùng, Thomas Karbowiak

Food biomacromolecules., Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 11, 2024

Abstract In the recent years, various strains of gut microbiota have been discovered to possess significant therapeutic potential, they are defined as next‐generation probiotics (NGPs). Akkermansia , Faecalibacterium Bacteriodes Eubacterium, and Bifidobacteria among typical NGP which exhibit several interesting bioactivities live biotherapeutics. However, some extremely sensitive oxygen, such prausnitzii . This hinders their cultivation large‐scale production. Therefore, it is essential develop a strategy protect them during production, storage, colonic administration. review, highlights key developed in alongside encapsulation strategies used them. The primary criterion for selecting encapsulating techniques feasibility be performed under strictly anaerobic conditions. Various processes selected according physical forms products, including liquid, gel, solid forms, well final shaping product. critical factors materials include biocompatibility, safety, effective oxygen barrier properties, an optimal release profile gastrointestinal tract. review discusses protection aimed at improving survival thereby effectiveness NGPs.

Language: Английский

3D printed spiral tube–like cellulose scaffold for oral delivery of probiotics DOI Creative Commons
Yue Zhang, Chenmeng Zhou, Feng Ma

et al.

Science Advances, Journal Year: 2024, Volume and Issue: 10(34)

Published: Aug. 23, 2024

Introducing specific strains of probiotics into the gut microbiome is a promising way to modulate intestinal treat various health conditions clinically. However, oral typically have temporary or limited impact on and overall benefits. Here, we reported 3D printed cellulose-derived spiral tube-like scaffold that enabled high efficacy delivery probiotics. Benefiting from unique surface pattern, this system can effectively extend retention time loaded in without invading nearby tissues, provide favorable environment for survival long-term colonization probiotics, influence ecosystem as dietary fiber after degradation. We demonstrate Roseburia intestinalis -loaded exerts noticeable impacts regulation gut-related diseases, including obesity inflammatory bowel disease; thus, universal platform

Language: Английский

Citations

6
Probiotic Bacterial Cellulose: A Bio-mediated Nanomaterial for Health Care Applications DOI
Mainak Chaudhuri, Nabanita Saha, Petr Sáha

et al.

Published: Jan. 1, 2025

Language: Английский

Citations

0
Design and Fabrication of Sustained Bacterial Release Scaffolds to Support the Microbiome DOI Creative Commons

Anne Marie Klein,

Nanang Qosim, Gareth R. Williams

et al.

Pharmaceutics, Journal Year: 2024, Volume and Issue: 16(8), P. 1066 - 1066

Published: Aug. 14, 2024

Fibres in the micro- and nanometre scale are suited to a broad range of applications, including drug delivery tissue engineering. Electrospinning is manufacturing method choice, but it has some limitations. Novel pressure-driven fibre-forming techniques, like pressurised gyration (PG), overcome these limitations; however, compatibility PG with biological materials not yet been evaluated detail. For first time, this limitation was investigated by optimising for microbial cell processing incorporating bacterial cultures into fibrous polymeric scaffolds sustained release. Multiple polymer–solvent systems were trialled, polyvinylpyrrolidone (PVP)/phosphate-buffered saline (PBS) 25% w/v, polyethylene oxide (PEO)/PBS 20% PVP/ethanol w/v. Rheological studies revealed surface tension PVP/PBS, PEO/PBS, be 73.2, 73.9, 22.6 mN/m, respectively. Scanning electron microscopy showed median fibre diameters between 9.8 μm 26.1 μm, PVP producing larger fibres. Overnight Bacillus subtilis then incorporated chosen solutions processed fibres using PG. The produced cell-loaded incubated LB broth assess viability encapsulated cells. Colony counts post-incubation PVP/PBS resulted 60% growth, PEO/PBS led 47% whereas did lead any growth. Based on results gathered during study, can concluded that offers promising way encapsulating cells other sensitive products while having many notable advantages compared electrospinning. This research demonstrates proof concept research-based evidence showcases potential as key disruptive innovation probiotic system design manufacturing.

Language: Английский

Citations

3
A Current Trend in Efficient Biopolymer Coatings for Edible Fruits to Enhance Shelf Life DOI Open Access
V. Ramkumar,

Subburayan Manickavasagam Suresh Kumar,

Mayakrishnan Gopiraman

et al.

Polymers, Journal Year: 2024, Volume and Issue: 16(18), P. 2639 - 2639

Published: Sept. 18, 2024

In recent years, biopolymer coatings have emerged as an effective approach for extending the shelf life of edible fruits. The invention coverings has innovation fruit life. Natural polymers, like chitosan, alginate, and pectin, are used to create these surfaces, which several uses, including creating a barrier that prevents water evaporation, spread living microbes, respiratory movement. These coatings’ primary benefits their environmental friendliness lack damage. This study highlights advancements made in creation usage coatings, highlighting how well they preserve quality, reduce post-harvest losses, satisfy consumer demand natural preservation methods. discusses usefulness coating terms preserving reducing waste, product’s Biopolymer potential sustainable solution synthetic preservatives sector is highlighted formulation process advances combine ingredients implications. essay focuses on essential methods, such new additives, effect safe healthy commercial alternatives.

Language: Английский

Citations

2
The investigation of the mechanism underlying variations in oxidative stress tolerance of Lacticaseibacillus paracasei resulting from fermentation methods through endogenous CRISPR-Cas9 editing methodology DOI
Pengyu Wu, Yutian Zhang,

Qiantong Shan

et al.

Food Microbiology, Journal Year: 2024, Volume and Issue: 127, P. 104697 - 104697

Published: Nov. 30, 2024

Language: Английский

Citations

2
Advances in Cellulose-Based Hydrogels: Current Trends and Challenges DOI Creative Commons
Bogdan-Marian Tofanica, А. М. Михаилиди, C. Samuil

et al.

Gels, Journal Year: 2024, Volume and Issue: 10(12), P. 842 - 842

Published: Dec. 20, 2024

This paper provides a solid foundation for understanding the synthesis, properties, and applications of cellulose-based gels. It effectively showcases potential these gels in diverse applications, particularly biomedicine, highlights key synthesis methods properties. However, to push field forward, future research should address gaps environmental impact, mechanical stability, scalability gels, while also considering how overcome barriers their industrial use. will ultimately allow realization large-scale, sustainable applications.

Language: Английский

Citations

2
Molecular mechanisms underlying the beneficial effects of fermented yoghurt prepared by nano-exopolysaccharide-producing Lactiplantibacillus plantarum LCC-605 based on untargeted metabolomic analysis DOI
Ying Yang,

Xiaotong Shi,

Junze Zhang

et al.

Food Chemistry, Journal Year: 2024, Volume and Issue: 465, P. 142068 - 142068

Published: Nov. 15, 2024

Language: Английский

Citations

1
Research on Development and Characterization of Composite Membranes Based on Hybrid Bacterial Cellulose Combined with Glycerol and Vegetable Residues for the Preservation of Fresh Fruit and Food DOI Creative Commons
Tuan Anh Nguyen, Xuan Huy Nguyen,

Thuy Van Ngo

et al.

Journal of Engineering, Journal Year: 2024, Volume and Issue: 2024, P. 1 - 13

Published: May 6, 2024

This study aims to develop a biocompatible and bioactive food-packaging composite film material. The material is based on bacterial cellulose (BC) microfibers from coconut jelly biomass combined with olive oil as carrier of antibacterial properties. A membrane was fabricated 20%, 30%, 40 wt % glycerol separately impregnated 1%, 2%, 3 in the presence BC. results SEM image structure morphology show that successfully uniform distribution BC, without losing its natural structure. initially applied preserve apples, research showed mass index did not change significantly (ranging 1.13 5.1 g); hardness through bearing test decrease. preservation time membranes, which are vegetable residues, extends up 20 days. highest concentration vitamin C soaked BC/glycerol 30%/olive 2% lowest BC membrane.

Language: Английский

Citations

1
Review: Biomacromolecules‐based encapsulation technologies for the protection of oxygen‐sensitive next‐generation probiotics DOI Creative Commons
Thị‐Thanh‐Trúc Phùng, Thomas Karbowiak

Food biomacromolecules., Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 11, 2024

Abstract In the recent years, various strains of gut microbiota have been discovered to possess significant therapeutic potential, they are defined as next‐generation probiotics (NGPs). Akkermansia , Faecalibacterium Bacteriodes Eubacterium, and Bifidobacteria among typical NGP which exhibit several interesting bioactivities live biotherapeutics. However, some extremely sensitive oxygen, such prausnitzii . This hinders their cultivation large‐scale production. Therefore, it is essential develop a strategy protect them during production, storage, colonic administration. review, highlights key developed in alongside encapsulation strategies used them. The primary criterion for selecting encapsulating techniques feasibility be performed under strictly anaerobic conditions. Various processes selected according physical forms products, including liquid, gel, solid forms, well final shaping product. critical factors materials include biocompatibility, safety, effective oxygen barrier properties, an optimal release profile gastrointestinal tract. review discusses protection aimed at improving survival thereby effectiveness NGPs.

Language: Английский

Citations

0