European journal of medical research,
Journal Year:
2025,
Volume and Issue:
30(1)
Published: Feb. 4, 2025
Abstract
Brain
tumor
treatment
remains
a
significant
challenge
due
to
their
high
mortality
and
resistance
current
therapies.
This
paper
discusses
the
promising
potential
of
hydrogel-based
nanoparticles
as
innovative
drug
delivery
systems
for
brain
therapy.
Extensive
characterization
techniques
reveal
ability
these
Nano-systems
demonstrate
prolonged
blood
circulation
targeted
delivery,
leading
improved
survival
rates.
Designed
with
optimized
physicochemical
characteristics,
effectively
cross
blood–brain
barrier,
circumventing
major
impediment
brain.
By
delivering
drugs
directly
bed,
enhance
therapeutic
outcomes
minimize
adverse
effects.
In
addition,
this
review
investigates
characterizing,
visualizing,
modifying
nanoparticles,
well
standing
challenges
research
avenues
clinical
application.
Further
investigations
are
encouraged
by
investigate
advancements
in
nanoparticle
approaches
tumors.
includes
investigating
tailored
hydrogels,
hybrid
systems,
computational
modeling,
integration
gene
therapy
immunotherapy
techniques.
The
study
also
addresses
need
enhanced
synthesis
techniques,
stability,
scalability,
cost-cutting
measures
overcome
obstacles
advance
use
treating
Graphical
abstract
Gels,
Journal Year:
2025,
Volume and Issue:
11(2), P. 88 - 88
Published: Jan. 23, 2025
There
is
ongoing
research
for
biomedical
applications
of
polyvinyl
alcohol
(PVA)-based
hydrogels;
however,
the
execution
this
has
not
yet
been
achieved
at
an
appropriate
level
commercialization.
Advanced
perception
necessary
design
and
synthesis
suitable
materials,
such
as
PVA-based
hydrogel
applications.
Among
polymers,
drawn
great
interest
in
owing
to
their
attractive
potential
with
characteristics
good
biocompatibility,
mechanical
strength,
apposite
water
content.
By
designing
approach
investigating
structure,
hydrogels
can
attain
superb
cytocompatibility,
flexibility,
antimicrobial
activities,
signifying
that
it
a
candidate
tissue
engineering
regenerative
medicine,
drug
delivery,
wound
dressing,
contact
lenses,
other
fields.
In
review,
we
highlight
current
progresses
on
explaining
diverse
usage
across
variety
areas.
We
explain
numerous
techniques
related
phenomena
based
these
materials.
This
review
may
stipulate
wide
reference
future
acumens
materials
extensive
Journal of Composites Science,
Journal Year:
2025,
Volume and Issue:
9(3), P. 133 - 133
Published: March 13, 2025
Severe
skin
injuries
such
as
burns
and
chronic
wounds
are
a
subject
of
interest
in
the
medical
field,
they
require
much
attention.
These
types
susceptible
to
serious
complications,
which
can
worsen
health
patients
reduce
their
quality
life.
Hydrogels
have
emerged
innovative
wound
dressings
for
treating
acute
wounds,
including
burns,
diabetic
foot
ulcers,
venous
leg
pressure
ulcers.
polymeric
networks
provide
moist
environment,
promote
cellular
migration,
offer
antimicrobial
properties,
being
recognized
superior
conventional
dressings.
This
review
aims
explore
recent
advancements
hydrogel-based
dressings,
emphasizing
state-of-the-art
technologies
used
this
purpose
trend
achieving
personalized
therapeutic
approaches.
Despite
promising
vitro
vivo
findings
described
review,
further
clinical
validation
large-scale
manufacturing
optimizations
required
widespread
adoption.
Gels,
Journal Year:
2025,
Volume and Issue:
11(2), P. 134 - 134
Published: Feb. 13, 2025
The
diketopyrrolopyrrole
(DPP)
core
is
widely
recognized
for
its
applications
in
organic
electronics
and
photonics
due
to
exceptional
electronic
optical
properties.
Recently,
DPP-based
materials
have
shown
remarkable
π-π
stacking
interactions
tunable
self-assembly,
making
them
promising
candidates
gel
formation.
However,
the
development
of
gels
remains
infancy,
primarily
hindered
by
challenges
such
as
limited
gelation
efficiency,
poor
mechanical
robustness,
sensitivity
environmental
conditions.
Overcoming
these
issues
crucial
unlocking
their
full
potential
functional
soft
materials.
This
review
compiles
analyzes
existing
studies
on
DPP-containing
systems,
highlighting
structural
versatility,
self-assembly
mechanisms,
advantages
over
conventional
gelators.
By
examining
works,
we
identify
key
strategies
DPP
formation,
evaluate
physicochemical
performance,
discuss
innovative
approaches
address
current
limitations.
Finally,
propose
future
research
directions
advance
field
establish
a
robust
platform
next-generation
The
discharge
of
silk
sericin
(SS)
as
waste
with
wastewater
presents
a
dual
challenge
in
terms
resource
utilization
and
environmental
protection.
In
this
study,
SS
was
extracted
from
silkworm
cocoons,
multifunctional
hydrogel
tetrakis
(hydroxymethyl)
phosphonium
sulfate
antibacterial
antioxidant
components
developed
cross-linked
polyvinyl
alcohol
agarose
(PATS)
to
provide
mechanical
properties
accelerate
wound
healing.
PATS
demonstrated
excellent
tensile
compressive
properties.
Furthermore,
exhibited
notable
capabilities
against
Escherichia
coli
Staphylococcus
aureus,
significantly
scavenged
the
production
free
radicals.
Additionally,
displayed
favorable
cytocompatibility
hemocompatibility.
Ultimately,
effectively
accelerated
healing
rat
full-thickness
skin
defect
model.
Therefore,
study
provides
theoretical
basis
for
development
dressings
highlights
potential
application
sustainable
biomaterials.
