Advanced Technologies for Large Scale Supply of Marine Drugs

Marine Drugs, Journal Year: 2025, Volume and Issue: 23(2), P. 69 - 69

Published: Feb. 7, 2025

Marine organisms represent a source of unique chemical entities with valuable biomedical potentialities, broad diversity, and complexity. It is essential to ensure reliable sustainable supply marine natural products (MNPs) for their translation into commercial drugs other products. From structural point view few exceptions, MNPs pharmaceutical importance derive from the so-called secondary metabolism organisms. When production strategies rely on macroorganisms, harvesting or culturing coupled extraction procedures frequently remain only alternative producing these compounds an industrial scale. Their can often be implemented laboratory scale cultures bacterial, fungal, microalgal sources. However, diverse approach, combining traditional methods modern synthetic biology biosynthesis strategies, must considered invertebrate MNPs, as they are usually naturally accumulated in very small quantities. This review offers comprehensive examination various addressing challenges related supply, synthesis, scalability. also underscores recent biotechnological advancements that likely transform current industrial-scale manufacturing pharmaceuticals derived

Language: Английский

Lipid- and Multivariate-Based Analyses to Determine Cell Response to pH Variations and Buffer Composition

Marine Biotechnology, Journal Year: 2025, Volume and Issue: 27(1)

Published: Feb. 1, 2025

Language: Английский