Biosensors,
Journal Year:
2022,
Volume and Issue:
12(5), P. 289 - 289
Published: May 1, 2022
The
detection
of
hypertension
(HT)
is
great
importance
for
the
early
diagnosis
cardiovascular
diseases
(CVDs),
as
subjects
with
high
blood
pressure
(BP)
are
asymptomatic
until
advanced
stages
disease.
present
study
proposes
a
classification
model
to
discriminate
between
normotensive
(NTS)
and
hypertensive
(HTS)
employing
electrocardiographic
(ECG)
photoplethysmographic
(PPG)
recordings
an
alternative
traditional
cuff-based
methods.
A
total
913
ECG,
PPG
BP
from
69
were
analyzed.
Then,
signal
preprocessing,
fiducial
points
extraction
feature
selection
performed,
providing
17
discriminatory
features,
such
pulse
arrival
transit
times,
that
fed
machine-learning-based
classifiers.
main
innovation
proposed
in
this
research
uncovers
relevance
previous
calibration
obtain
accurate
HT
risk
assessment.
This
aspect
has
been
assessed
using
both
close
distant
time
test
measurements
respect
calibration.
k-nearest
neighbors-classifier
provided
best
outcomes
accuracy
new
before
51.48%.
inclusion
just
one
measurement
into
improved
by
30%,
reaching
gradually
more
than
96%
six
measurements.
Accuracy
decreased
distance
calibration,
but
remained
outstanding
even
days
after
Thus,
use
ECG
combined
subject
can
significantly
improve
discrimination
NTS
HTS
individuals.
strategy
could
be
implemented
wearable
devices
assessment
well
prevent
CVDs.
Advanced Science,
Journal Year:
2022,
Volume and Issue:
9(30)
Published: Aug. 28, 2022
Abstract
Recently,
bioelectronic
devices
extensively
researched
and
developed
through
the
convergence
of
flexible
biocompatible
materials
electronics
design
that
enables
more
precise
diagnostics
therapeutics
in
human
health
care
opens
up
potential
to
expand
into
various
fields,
such
as
clinical
medicine
biomedical
research.
To
establish
an
accurate
stable
bidirectional
bio‐interface,
protection
against
external
environment
high
mechanical
deformation
is
essential
for
wearable
devices.
In
case
implantable
bioelectronics,
special
encapsulation
optimized
designs
configurations
provide
electronic
stability
functionality
are
required
accommodating
organ
properties,
lifespans,
functions
biofluid
environment.
Here,
this
study
introduces
recent
developments
ultra‐thin
encapsulations
with
novel
can
preserve
or
even
improve
electrical
performance
bio‐integrated
by
supporting
safety
from
destruction
contamination
well
optimizing
use
systems
physiological
environments.
addition,
a
summary
materials,
methods,
characteristics
most
widely
used
technologies
introduced,
thereby
providing
strategic
selection
appropriate
choices
recently
bioelectronics.
Journal of Cardiovascular Development and Disease,
Journal Year:
2023,
Volume and Issue:
10(2), P. 74 - 74
Published: Feb. 9, 2023
Arterial
hypertension
(AH)
is
a
progressive
issue
that
grows
in
importance
with
the
increased
average
age
of
world
population.
The
potential
role
artificial
intelligence
(AI)
its
prevention
and
treatment
firmly
recognized.
Indeed,
AI
application
allows
personalized
medicine
tailored
for
each
patient.
Specifically,
this
article
reviews
benefits
AH
management,
pointing
out
diagnostic
therapeutic
improvements
without
ignoring
limitations
innovative
scientific
approach.
Consequently,
we
conducted
detailed
search
on
applications
AH:
articles
(quantitative
qualitative)
reviewed
paper
were
obtained
by
searching
journal
databases
such
as
PubMed
subject-specific
professional
websites,
including
Google
Scholar.
terms
included
intelligence,
neural
network,
deep
learning,
machine
big
data,
arterial
hypertension,
blood
pressure,
pressure
measurement,
cardiovascular
disease,
medicine.
AI-based
systems
could
help
continuously
monitor
BP
using
wearable
technologies;
particular,
can
be
estimated
from
photoplethysmograph
(PPG)
signal
smartphone
or
smartwatch
DL.
Furthermore,
thanks
to
ML
algorithms,
it
possible
identify
new
genes
early
diagnosis
complications.
Moreover,
integrating
omics-based
technologies
will
lead
definition
trajectory
hypertensive
patient
use
most
appropriate
drug.
However,
not
free
technical
issues
biases,
over/underfitting,
“black-box”
nature
many
data
privacy.
In
conclusion,
change
clinical
practice
identifying
trajectories
new,
care
plans
predicting
patients’
risks
necessary
therapy
adjustments
due
changes
disease
progression
and/or
response.
Sensors,
Journal Year:
2022,
Volume and Issue:
22(10), P. 3953 - 3953
Published: May 23, 2022
Accurate
estimation
of
blood
pressure
(BP)
waveforms
is
critical
for
ensuring
the
safety
and
proper
care
patients
in
intensive
units
(ICUs)
intraoperative
hemodynamic
monitoring.
Normal
cuff-based
BP
measurements
can
only
provide
systolic
(SBP)
diastolic
(DBP).
Alternatively,
waveform
be
used
to
estimate
a
variety
other
physiological
parameters
provides
additional
information
about
patient’s
health.
As
result,
various
techniques
are
being
proposed
accurately
estimating
waveforms.
The
purpose
this
review
summarize
current
state
knowledge
regarding
waveform,
three
methodologies
(pressure-based,
ultrasound-based,
deep-learning-based)
noninvasive
research
feasibility
employing
these
strategies
at
home
as
well
ICUs.
Additionally,
article
will
discuss
physical
concepts
underlying
both
invasive
measurements.
We
historical
measurements,
standard
clinical
procedures,
more
recent
innovations
Although
technique
has
not
been
validated,
it
expected
that
precise,
available
near
future
due
its
enormous
potential.
Frontiers in Cardiovascular Medicine,
Journal Year:
2022,
Volume and Issue:
9
Published: July 11, 2022
Novel
smartwatch-based
cuffless
blood
pressure
(BP)
measuring
devices
are
coming
to
market
and
receive
FDA
CE
labels.
These
often
insufficiently
validated
for
clinical
use.
This
study
aims
investigate
a
recently
CE-cleared
smartwatch
using
BP
measurement
in
population
with
normotensive
hypertensive
individuals
scheduled
24-h
measurement.Patients
that
were
ambulatory
monitoring
(ABPM)
recruited
received
an
additional
Samsung
Galaxy
Watch
Active
2
simultaneous
on
their
opposite
arm.
After
calibration,
patients
asked
measure
as
much
possible
period.
Manual
activation
of
the
is
necessary
BP.
Accuracy
was
calculated
sensitivity,
specificity,
positive
negative
predictive
values
ROC
curves.
Bland-Altman
method
Taffé
methods
used
bias
precision
assessment.
variability
average
real
variability,
standard
deviation
coefficient
variation.Forty
included.
demonstrated
proportional
bias,
which
low
systolic
BPs
overestimated,
high
underestimated.
Diastolic
all
increasing
toward
lower
BPs.
Sensitivity
specificity
detecting
and/or
diastolic
hypertension
83
41%,
respectively.
curves
demonstrate
area
under
curve
(AUC)
0.78
0.93
hypertension.
systematically
higher
ABPM
measurements
compared
measurements.This
demonstrates
by
show
systematic
calibration
point,
overestimating
underestimating
BPs,
when
investigated
both
patients.
Standards
traditional
non-invasive
sphygmomanometers
not
met,
but
these
standards
fully
applicable
devices,
emphasizing
urgent
need
new
devices.
The
yet
ready
usage.
Future
studies
needed
further
validate
wearable
also
possibilities
non-invasive,
high-frequency
monitoring.
Nanomaterials,
Journal Year:
2023,
Volume and Issue:
13(5), P. 852 - 852
Published: Feb. 24, 2023
Flexible
sensors
have
been
extensively
employed
in
wearable
technologies
for
physiological
monitoring
given
the
technological
advancement
recent
years.
Conventional
made
of
silicon
or
glass
substrates
may
be
limited
by
their
rigid
structures,
bulkiness,
and
incapability
continuous
vital
signs,
such
as
blood
pressure
(BP).
Two-dimensional
(2D)
nanomaterials
received
considerable
attention
fabrication
flexible
due
to
large
surface-area-to-volume
ratio,
high
electrical
conductivity,
cost
effectiveness,
flexibility,
light
weight.
This
review
discusses
transduction
mechanisms,
namely,
piezoelectric,
capacitive,
piezoresistive,
triboelectric,
sensors.
Several
2D
used
sensing
elements
BP
are
reviewed
terms
materials,
performance.
Previous
works
on
presented,
including
epidermal
patches,
electronic
tattoos,
commercialized
patches.
Finally,
challenges
future
outlook
this
emerging
technology
addressed
non-invasive
monitoring.
ACS Nano,
Journal Year:
2024,
Volume and Issue:
18(27), P. 17407 - 17438
Published: June 26, 2024
Continuous
blood
pressure
(BP)
tracking
provides
valuable
insights
into
the
health
condition
and
functionality
of
heart,
arteries,
overall
circulatory
system
humans.
The
rapid
development
in
flexible
wearable
electronics
has
significantly
accelerated
advancement
BP
monitoring
technologies.
However,
several
persistent
challenges,
including
limited
sensing
capabilities
stability
sensors,
poor
interfacial
between
sensors
skin,
low
accuracy
estimation,
have
hindered
progress
monitoring.
To
address
these
comprehensive
innovations
materials
design,
device
development,
optimization,
modeling
been
pursued
to
improve
performance
systems.
In
this
review,
we
highlight
latest
advancements
systems
toward
continuous
noninvasive
with
a
primary
focus
on
integration,
theoretical
algorithms.
Existing
potential
solutions,
further
research
directions
are
also
discussed
provide
technical
guidance
for
future
ambulatory
measurement
enhanced
capability,
robustness,
long-term
accuracy.
Advances
in
stretchable
and
flexible
sensors
are
meeting
the
demands
of
an
expanding
range
applications,
such
as
wearable
healthcare,
vivo
monitoring,
soft
interactive
robots.
Unlike
conventional
rigid
sensors,
elastic
material-based
more
adaptable
to
applied
objects
which
involve
dynamic
irregular
surfaces.
Flexible
optical
fiber
offer
superior
advantages
over
electronic
including
high
sensitivity,
rapid
response
time,
biocompatibility,
immunity
electromagnetic
interference,
enhanced
safety.
These
desirable
features
have
propelled
them
become
a
prominent
category,
witnessing
substantial
advancements
recent
years.
This
technology
has
successfully
facilitated
diverse
human
health
biological
measurements,
human-machine
interfaces.
In
this
review,
we
provide
concise
overview
latest
developments
sensing,
focusing
on
key
aspects,
preparation
materials,
methodologies,
applications.
Furthermore,
valuable
insights
into
potential
challenges
opportunities
that
lie
ahead
field
sensing
technology.