Non-invasive method for blood glucose monitoring using ECG signal DOI Open Access
Khadidja Fellah Arbi,

Sofiane Soulimane,

Fayçal Saffih

et al.

Polish Journal of Medical Physics And Engineering, Journal Year: 2023, Volume and Issue: 29(1), P. 1 - 9

Published: Feb. 1, 2023

Abstract Introduction: Tight glucose monitoring is crucial for diabetic patients by using a Continuous Glucose Monitor (CGM). The existing CGMs measure the Blood Concentration (BGC) from interstitial fluid. These technologies are quite expensive, and most of them invasive. Previous studies have demonstrated that hypoglycemia hyperglycemia episodes affect electrophysiology heart. However, they did not determine cohort relationship between BGC ECG parameters. Material method: In this work, we propose new method determining surface signals. Recurrent Convolutional Neural Networks (RCNN) were applied to segment Then, extracted features employed two mathematical equations. This has been tested on 04 over multiple days D1namo dataset, signals instead intracardiac signal. Results: We able with an accuracy 94% RCNN algorithm. According results, proposed was estimate Mean Absolute Error (MAE) 0.0539, Squared (MSE) 0.1604. addition, linear confirmed in paper. Conclusion: paper, potential use BGC. Additionally, features. That fact will open perspectives further research, namely physiological models. Furthermore, findings point possible application wearable devices non-invasive continuous blood via machine learning.

Language: Английский

The LOD paradox: When lower isn't always better in biosensor research and development DOI
Hichem Moulahoum, Faezeh Ghorbanizamani

Biosensors and Bioelectronics, Journal Year: 2024, Volume and Issue: 264, P. 116670 - 116670

Published: Aug. 13, 2024

Language: Английский

Citations

19

Electrochemically Synthesized MIP Sensors: Applications in Healthcare Diagnostics DOI Creative Commons
Akinrinade George Ayankojo, Jekaterina Reut, Vitali Syritski

et al.

Biosensors, Journal Year: 2024, Volume and Issue: 14(2), P. 71 - 71

Published: Jan. 30, 2024

Early-stage detection and diagnosis of diseases is essential to the prompt commencement treatment regimens, curbing spread disease, improving human health. Thus, accurate disease biomarkers through development robust, sensitive, selective diagnostic tools has remained cutting-edge scientific research for decades. Due their merits being selective, stable, simple, having a low preparation cost, molecularly imprinted polymers (MIPs) are increasingly becoming artificial substitutes natural receptors in design state-of-the-art sensing devices. While there different MIP approaches, electrochemical synthesis presents unique outstanding method chemical applications, allowing direct formation polymer on transducer as well simplicity tuning film properties, thus accelerating trend commercial MIP-based sensors. This review evaluates recent achievements applications electrosynthesized sensors clinical analysis biomarkers, identifying major trends highlighting interesting perspectives realization MIP-endowed testing devices rapid determination prevailing diseases.

Language: Английский

Citations

16

Recent Advancement in Biofluid-Based Glucose Sensors Using Invasive, Minimally Invasive, and Non-Invasive Technologies: A Review DOI Creative Commons
Vundrala Sumedha Reddy, Bhawana Agarwal, Zhen Ye

et al.

Nanomaterials, Journal Year: 2022, Volume and Issue: 12(7), P. 1082 - 1082

Published: March 25, 2022

Biosensors have potentially revolutionized the biomedical field. Their portability, cost-effectiveness, and ease of operation made market for these biosensors to grow rapidly. Diabetes mellitus is condition having high glucose content in body, it has become one very common conditions that leading deaths worldwide. Although still no cure or prevention, if monitored treated with appropriate medication, complications can be hindered mitigated. Glucose body detected using various biological fluids, namely blood, sweat, urine, interstitial tears, breath, saliva. In past decade, there been an influx potential biosensor technologies continuous level estimation. This literature review provides a comprehensive update on recent advances field biofluid-based sensors detection terms methods, methodology materials used.

Language: Английский

Citations

53

Real-Time Measurement of Liquid Permittivity Through Label-Free Meandered Microwave Sensor DOI
Sina Kiani, Pejman Rezaei, Mina Fakhr

et al.

IETE Journal of Research, Journal Year: 2023, Volume and Issue: 70(5), P. 4606 - 4616

Published: July 9, 2023

In this paper, a microwave sensor with meandered microstrip structure is introduced to measure the permittivity of various liquids. The performance based on change operating resonance frequency during absence and presence materials in sensing area. study, liquids including ethanol, methanol, aqueous glucose solution, deionized water have been selected as samples under test. proposed has implemented RO4003 substrate dimensions 35 × 20 0.508 mm3 6.21 GHz free load state Q-factor 506. When are present area, shifts from 5.42 3.27 GHz. sensitivity 0.64% obtained for presented sensor. Compact size, linearity changes, low cost most important advantages can be used fields industrial, medical, diagnostic due its performance.

Language: Английский

Citations

39

Triboelectric nanogenerators for wearable sensing applications: A system level analysis DOI Creative Commons

R.L. Bulathsinghala,

Wen Ding, R.D.I.G. Dharmasena

et al.

Nano Energy, Journal Year: 2023, Volume and Issue: 116, P. 108792 - 108792

Published: Aug. 18, 2023

Wearable sensing is a rapidly expanding research area with significant future potential and impact, encompassing lifestyle, sports & fitness healthcare applications. The target of the next generation wearable technologies to be energy efficient, accurate, intelligent integrate seamlessly body as second skin. Triboelectric Nanogenerators (TENGs), which use static charging electrostatic induction convert movements into electrical pulses, are envisioned key addition wearables due their self-powered harvesting capabilities. TENGs offer high instantaneous outputs, low cost, flexibility comfort, presenting for autonomous maintenance free operation This paper provides comprehensive review on cutting-edge developments in TENG based systems. Herein, we present holistic system level assessment where analyse power functions well related management, signal acquisition, decision making, connectivity integration processes. drawbacks most critical challenges existing technology discussed, perspectives routes overcome them.

Language: Английский

Citations

32

The Applications of Electrochemical Immunosensors in the Detection of Disease Biomarkers: A Review DOI Creative Commons

Huinan Chen,

Jialü Zhang, Rong Huang

et al.

Molecules, Journal Year: 2023, Volume and Issue: 28(8), P. 3605 - 3605

Published: April 20, 2023

Disease-related biomarkers may serve as indicators of human disease. The clinical diagnosis diseases largely benefit from timely and accurate detection biomarkers, which has been the subject extensive investigations. Due to specificity antibody antigen recognition, electrochemical immunosensors can accurately detect multiple disease including proteins, antigens, enzymes. This review deals with fundamentals types immunosensors. are developed using three different catalysts: redox couples, typical biological enzymes, nanomimetic also focuses on applications those in cancer, Alzheimer’s disease, novel coronavirus pneumonia other diseases. Finally, future trends addressed terms achieving lower limits, improving electrode modification capabilities developing composite functional materials.

Language: Английский

Citations

25

Non-invasive blood glucose monitoring technology in diabetes management: review DOI Open Access
Jeban Chandir Moses, Sasan Adibi, Nilmini Wickramasinghe

et al.

mHealth, Journal Year: 2024, Volume and Issue: 10, P. 9 - 9

Published: Jan. 1, 2024

Abstract: Diabetes is one of the leading non-communicable diseases globally, adversely impacting an individual's quality life and adding a considerable burden to healthcare systems. The necessity for frequent blood glucose (BG) monitoring inconveniences associated with self-monitoring BG, such as pain discomfort, has motivated development non-invasive BG approaches. However, current research progress slow, only few devices have made progress. Hence, we evaluate available technologies validated against recordings provide future direction design, develop, deploy integrated emerging technologies. We searched five databases, Embase, MEDLINE, Proquest, Scopus, Web Science, assess technology's scope in diabetes management paradigm published from 2000 2020. A total three approaches screening, including saliva, skin, breath, were identified discussed. observed statistical relationship between measurements obtained methods standard clinical measures. Opportunities exist advance facilitate early technology adoption practice. results promise validity; however, formulating regulatory guidelines could foresee deployment approved Further, prospects are there systems mobile technologies, data analytics, internet things (IoT) deliver personalised system.

Language: Английский

Citations

10

Review of Microwave Near-Field Sensing and Imaging Devices in Medical Applications DOI Creative Commons
C. Origlia, D. O. Rodriguez-Duarte, J. A. Tobón Vasquez

et al.

Sensors, Journal Year: 2024, Volume and Issue: 24(14), P. 4515 - 4515

Published: July 12, 2024

Microwaves can safely and non-destructively illuminate penetrate dielectric materials, making them an attractive solution for various medical tasks, including detection, diagnosis, classification, monitoring. Their inherent electromagnetic properties, portability, cost-effectiveness, the growth in computing capabilities have encouraged development of numerous microwave sensing imaging systems field, with potential to complement or even replace current gold-standard methods. This review aims provide a comprehensive update on latest advances applications microwaves, particularly focusing near-field ones working within 1-15 GHz frequency range. It specifically examines significant strides clinical devices brain stroke diagnosis breast cancer screening, continuous blood glucose The technical implementation algorithmic aspects prototypes are discussed detail, transceiver systems, radiating elements (such as antennas sensors), algorithms. Additionally, it provides overview other promising cutting-edge applications, such knee injuries colon polyps torso scanning image-based monitoring thermal therapy intervention. Finally, discusses challenges achieving engagement microwave-based technologies explores future perspectives.

Language: Английский

Citations

9

Enzymatic biosensor based on dendritic gold nanostructure and enzyme precipitation coating for glucose sensing and detection DOI
Ran Bi, Xiaoyan Ma, Kunpeng Miao

et al.

Enzyme and Microbial Technology, Journal Year: 2022, Volume and Issue: 162, P. 110132 - 110132

Published: Sept. 16, 2022

Language: Английский

Citations

29

Tackling the challenges of developing microneedle-based electrochemical sensors DOI

Hilmee Abdullah,

Tonghathai Phairatana, Itthipon Jeerapan

et al.

Microchimica Acta, Journal Year: 2022, Volume and Issue: 189(11)

Published: Nov. 1, 2022

Language: Английский

Citations

29