Real-Time Detection of Yeast Growth on Solid Medium through Passive Microresonator Biosensor

Biosensors, Journal Year: 2024, Volume and Issue: 14(5), P. 216 - 216

Published: April 26, 2024

This study presents a biosensor fabricated based on integrated passive device (IPD) technology to measure microbial growth solid media in real-time. Yeast (Pichia pastoris, strain GS115) is used as model organism demonstrate performance. The comprises an interdigital capacitor the center with helical inductive structure surrounding it. Additionally, 12 air bridges are added increase strength of electric field radiated by at same height. Feasibility verified using capacitive biosensor, and change capacitance values during detection process yeast indicates that can induce changes electrical parameters. proposed IPD-based drop-added 3 mm medium for 100 h operating frequency 1.84 GHz. resonant amplitude varies continuously from 24 72 due colony height vertical yeast, maximum 0.21 dB. overall measurement results also fit well Gompertz curve. between then analyzed reveals linear relationship time coefficient determination 0.9844, indicating suitable monitoring growth. Thus, proved have potential proliferation detection.

Language: Английский

Terahertz metamaterial-prism hybrid sensors for microorganisms detection

Optics Express, Journal Year: 2024, Volume and Issue: 32(27), P. 48915 - 48915

Published: Dec. 9, 2024

In this study, we developed terahertz (THz) metamaterial devices with attenuated total reflection (ATR) geometries for biosensing applications. This was achieved by transferring the patterns fabricated on a polyimide film to prism-top surface. We characterized resonance characteristics of metasurfaces different THz wave polarizations and gap structure orientations in metamaterials. The resonances exhibited sharp compared normal incidence case; quality factor increased from 3.3 6.0. For applications, measured resonant-frequency shift hybrid device depositing yeast cells. sensitivity terms number density 3.4 times that Si substrate under incidence, which presented 4.1-fold increase figure merit. based finite-difference time-domain simulations successfully reproduced our experimental results, including enhanced devices.

Language: Английский

Mechanical Control of Polaritonic States in Lead Halide Perovskite Phonons Strongly Coupled in THz Microcavity

The Journal of Physical Chemistry Letters, Journal Year: 2023, Volume and Issue: 14(46), P. 10318 - 10327

Published: Nov. 9, 2023

We demonstrate the generation and control of polaritonic states in perovskite phonon polaritons, which are strongly coupled middle a flexible Fabry–Perot cavity. fabricated films on microporous substrate coated with graphene oxide, led to virtually free-standing film incorporated into microcavity. Rabi splitting was observed when cavity resonance tune that phonons. The energy increased as thickness increased, reaching 1.9 meV, is 2.4-fold higher than criterion for strong coupling regime. obtained dispersion curves various thicknesses exhibiting two polariton branches; clear beats between branches were time domain. Flexible devices phonons enable macroscopic over through bending processes, add an additional degree freedom manipulation devices.

Language: Английский