Exploring the repeatability of pulse arrival time in healthy subjects: A test-retest approach

Indian Journal of Physiology and Pharmacology, Journal Year: 2024, Volume and Issue: 0, P. 1 - 8

Published: Oct. 15, 2024

Objectives: Vascular ageing is increasingly being recognised as a vital marker of cardiovascular morbidity and mortality. Assessment vascular stiffness an important parameter in this context. Pulse arrival time (PAT) assessed using photoplethysmography (PPG) digital electrocardiogram (ECG) signals feasible cost-effective for assessment. However, there are few, if any, studies that have the test-retest repeatability over time. Materials Methods: We computed PAT finger PPG Lead II ECG measured it sequentially at five instances period 1 month 21 healthy adults (10 males 11 females). Mean diastolic blood pressure (MBP DBP) heart rate (HR) were also each visit. A novel parameter, normalised HR 75 (PAT-75), was computed. PAT-75 compared these visits repeated measures analysis variance. The intraclass correlation coefficient (ICC) used to assess reliability parameter. Results: MBP, DBP, values did not show any difference between visits. significantly different lower afternoon day forenoon. ICC demonstrated only moderate (ICC = 0.57), with further reduction observed 0.38). Conclusion: moderately repeatable on evaluation 1-month period. This finding may implications large-scale applicability technology, therefore, we propose investigation into large cohorts.

Language: Английский

Custom Silicone Vessels for In Vitro Investigations on Vascular Ageing using Photoplethysmography

Published: July 15, 2024

Cardiovascular diseases (CVD) remain a major health challenge, affecting millions of individuals. Alongside the impact CVD, natural process vascular ageing contributes to changes in system, potentially compromising cardiovascular by causing arterial stiffness. Current clinical methods for assessment often require referrals from General Practitioners, leading delays and patient anxiety. Photoplethysmography (PPG), an optical sensing technique employed numerous wearables, holds promise assessing health, particularly context ageing. This paper presents study where novel customisable vessel-tissue phantoms simulate system vitro were implemented. Various additives silicone elastomer explored their on vessel wall thickness elasticity. The results demonstrate that formulation significantly affect mechanical properties developed vessels. In PPG signals acquired customised phantoms. Tests have shown statistical difference between two with vessels varying paves way investigating further potential as indicator

Language: Английский

Advances, Benefits, and Challenges of Wearable Sensors for Healthcare and Stress Management: A Focus on Hemodynamic Parameters and Cortisol Measurement

Published: Nov. 26, 2024

Language: Английский