Feasibility of Photoplethysmography in Detecting Arterial Stiffness in Hypertension DOI Creative Commons
Parmis Karimpour, James M. May, P. A. Kyriacou

et al.

Photonics, Journal Year: 2025, Volume and Issue: 12(5), P. 430 - 430

Published: April 29, 2025

Asymptomatic peripheral artery disease (PAD) poses a silent risk, potentially leading to severe conditions if undetected. Integrating new screening tools into routine general practitioner (GP) visits could enable early detection. This study investigates the feasibility of photoplethysmography (PPG) monitoring for assessing vascular health across different blood pressure (BP) conditions. Custom femoral phantoms representing healthy (0.82 MPa), intermediate (1.48 and atherosclerotic (2.06 MPa) vessels were tested under hypertensive, normotensive, hypotensive evaluate PPG’s ability distinguish between states. Extracted features from PPG signal, including amplitude, area curve (AUC), median upslope–downslope ratio, end datum difference, analysed. Kruskal–Wallis tests revealed significant differences unhealthy BP states, supporting as tool. The fiducial points second derivative signal (SDPPG) ba ratio was most pronounced hypertensive (ranging –2.13 –2.06), suggesting change in wall distensibility. Under normotensive conditions, difference ratios smaller (0.01), no meaningful observed reduced sensitivity this metric at lower perfusion pressures. Intermediate states challenging detect, particularly hypotension, need further research. Nonetheless, highlights promise identifying stiffness.

Language: Английский

Feasibility of Photoplethysmography in Detecting Arterial Stiffness in Hypertension DOI Creative Commons
Parmis Karimpour, James M. May, P. A. Kyriacou

et al.

Photonics, Journal Year: 2025, Volume and Issue: 12(5), P. 430 - 430

Published: April 29, 2025

Asymptomatic peripheral artery disease (PAD) poses a silent risk, potentially leading to severe conditions if undetected. Integrating new screening tools into routine general practitioner (GP) visits could enable early detection. This study investigates the feasibility of photoplethysmography (PPG) monitoring for assessing vascular health across different blood pressure (BP) conditions. Custom femoral phantoms representing healthy (0.82 MPa), intermediate (1.48 and atherosclerotic (2.06 MPa) vessels were tested under hypertensive, normotensive, hypotensive evaluate PPG’s ability distinguish between states. Extracted features from PPG signal, including amplitude, area curve (AUC), median upslope–downslope ratio, end datum difference, analysed. Kruskal–Wallis tests revealed significant differences unhealthy BP states, supporting as tool. The fiducial points second derivative signal (SDPPG) ba ratio was most pronounced hypertensive (ranging –2.13 –2.06), suggesting change in wall distensibility. Under normotensive conditions, difference ratios smaller (0.01), no meaningful observed reduced sensitivity this metric at lower perfusion pressures. Intermediate states challenging detect, particularly hypotension, need further research. Nonetheless, highlights promise identifying stiffness.

Language: Английский

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