Repetitive transcranial magnetic stimulation for motor function in stroke: a systematic review and meta-analysis of randomized controlled studies

Systematic Reviews, Journal Year: 2025, Volume and Issue: 14(1)

Published: Feb. 24, 2025

This study aimed to systematically evaluate the safety and effectiveness of repetitive transcranial magnetic stimulation (rTMS) in treating motor dysfunction stroke patients. A systematic search was conducted five online databases, namely, Medline, EMBASE, Cochrane Central Register Controlled Trials (CENTRAL), CINAHL, SPORTDiscus, from their inception July 29, 2024. Studies meeting predetermined inclusion criteria were included. The data analyzed using RevMan 5.4.1 software Stata 15.0. subgroup analysis based on various disease stages intervention frequencies. overall effects estimated either fixed model or random model, with standardized mean differences (SMDs). level evidence assessed Grading Recommendations, Assessment, Development Evaluation (GRADE) framework. total 70 studies encompassing 2951 survivors results quantitative revealed that application 1 Hz rTMS over contralesional primary cortex (M1) significantly improved function during both early stage (< month) moderate effect size (n = 443, SMD 0.44, 95% CI 0.24 0.63, P < 0.00001, I2 47%, fixed-effect model) recovery period (1–6 months) 233, 0.61, 0.34 0.87, 0.0001, 33%, model). In context activities daily living (ADLs), M1 can lead improvements ADLs among individuals 343, 0.67, 0.44 0.89, 79%, However, support improve chronic phase (> 6 is insufficient. Moderate- high-quality suggests may enhance independence ADL (within effect. Nonetheless, as for efficacy 3, 5, 10, 20 treatment after stroke, it needs be further determined. It important interpret these findings caution clinical practice due small sample sizes low quality reviewed. INPLASY, Registration number INPLASY202360042. DOI https://doi.org/10.37766/inplasy2023.6.0042 .

Language: Английский

Clinical Application Research on Stroke Situational Intelligent Rehabilitation Training System Based on Wearable Devices: A Randomized Controlled Trial

Healthcare, Journal Year: 2025, Volume and Issue: 13(7), P. 708 - 708

Published: March 23, 2025

Background/Objectives: With the advancement of intelligent sensing technology, rehabilitation systems based on wearable devices have a positive impact functional recovery and quality life stroke patients. This study aims to evaluate application value contextualized training system for survivors, which is devices, in motor function impairments following stroke. Methods: A randomized controlled trial design was employed, 100 patients were randomly divided into control group (n = 50, receiving standard physical therapy interventions) an experimental 50). The additionally underwent interventions assessments through device-based contextual system, with sessions conducted twice daily 30 min each, five days week, over duration eight weeks. Both groups clinical scale evaluations data collection before after treatment, primary outcome measures including ability (Fugl-Meyer Assessment, FMA), activities living (Modified Barthel Index, MBI), participation therapy. intervention effects both compared weeks rehabilitation. Results: Prior intervention, there no significant differences Fugl-Meyer Assessment (FMA) Modified Index (MBI) scores between (p > 0.05). After rehabilitation, demonstrated significantly superior performance (FMA scores) (MBI < 0.01). Conclusions: enhances survivors. Compared traditional methods, it improves patient adherence overall outcomes.

Language: Английский

Effects of repetitive transcranial magnetic stimulation on lower extremity motor function and optimal parameters in stroke patients with different stages of stroke: a systematic evaluation and meta-analysis

Frontiers in Neurology, Journal Year: 2024, Volume and Issue: 15

Published: July 26, 2024

Repetitive transcranial magnetic stimulation (rTMS), as an emerging non-invasive neuromodulation technique, is now widely employed in rehabilitation therapy. The purpose of this paper to comprehensively summarize existing evidence regarding rTMS intervention for lower limb motor function patients at different stages stroke.

Language: Английский