Cichorium intybus L., Asteraceae: Taxonomy, chemical composition and pharmacological activity DOI Open Access

Filip Balaž,

Ana Tomás,

Nevena Grujić

et al.

Hrana i ishrana, Journal Year: 2024, Volume and Issue: 65(1), P. 1 - 9

Published: Jan. 1, 2024

Cichorium intybus L. (chicory), Asteraceae, is extensively recognized for its historical and modern uses in healthcare, agriculture, dietary practices. This study highlights the taxonomy, bioactive compounds, therapeutic properties of chicory. The species rich substances, such as inulin, phenolic acids (e.g., chlorogenic caffeic acids), sesquiterpene lactones, flavonoids quercetin luteolin). These phytochemicals are key to free radical scavenging, inflammation-modulating hepatoprotective action, microbial growth inhibition, anthelmintic blood sugar regulation. Inulin serves a prebiotic fiber, promoting gut health metabolic regulation, while exhibit potent antioxidant anticancer activities. Sesquiterpene lactones contribute anti-inflammatory antimicrobial effects, whereas enhance plant's potential by modulating biological pathways. Chicory's pharmacological applications extend liver protection, glucose metabolism immune modulation, underscoring managing chronic diseases. Despite extensive profile, further clinical studies necessary confirm efficacy, establish optimal dosages, explore long-term safety. work supports integration chicory into functional foods pharmaceutical formulations, leveraging diverse benefits address global challenges.

Language: Английский

Asteraceae in Pakistan and Kashmir with special emphasis on distribution pattern and endemism DOI
Muhammad Naeem Qaiser, Anjum Perveen, J. B. Alam

et al.

Genetic Resources and Crop Evolution, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 21, 2025

Language: Английский

Citations

0
Biological potential and therapeutic effectiveness with diverse signaling pathways of phyto-product chicoric acid: a comprehensive review with computational evidence DOI

Muhammad Nazir,

Iqra Farzeen,

Saima Zafar

et al.

Naunyn-Schmiedeberg s Archives of Pharmacology, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 27, 2025

Language: Английский

Citations

0
Evaluation of Inulin and Polyphenol Content and the Cytotoxicity of Cichorium intybus L. var. foliosum Root Extracts Obtained by Pectinase- and Pressure-Assisted Extraction DOI Open Access
Łukasz Duda, Grażyna Budryn, Monika A. Olszewska

et al.

Nutrients, Journal Year: 2025, Volume and Issue: 17(6), P. 1040 - 1040

Published: March 16, 2025

Background: Cichorium intybus L., a member of the Asteraceae family, has numerous health-promoting properties that categorize its preparations as functional foods and herbal medicines. Most previous research focused on root C. var. sativum (industrial chicory) rich source inulin, while witloof variety (C. foliosum) is less explored. Objectives: This study aimed to evaluate cytotoxicity foliosum extracts obtained with different extraction protocols analyze their polysaccharide polyphenol content. Methods: Freeze-dried were prepared using water three methods: pectinase-assisted, pressure-assisted, combination both. The contents total polyphenols, caffeic acid derivatives in measured by Layne–Eynon, Folin–Ciocalteu, UHPLC-PDA methods, respectively. Cytotoxicity inulin was tested vitro L929 cell line, MTT method, paracetamol reference standard. Results: Inulin levels ranged from 43.88 50.95 g/100 g dry matter (dm), polyphenols between 816.7 906.4 mg/100 dm, phenolic acids 11.50 187.1 pressure-assisted yielding highest phytochemical recovery. tests showed IC50 values 4.72 7.31 mg/mL for extracts, compared 3.02 19.77 inulin. Conclusions: Given high content active compounds low cytotoxicity, merit further into medicinal properties. Pressure-assisted recommended effective chicory.

Language: Английский

Citations

0
Research on Quality Evaluation of the Seeds of Cichorium glandulosum Boiss. et Huet. DOI Creative Commons
Chen Xu,

Jian‐Shuang Jiang,

Fengling Li

et al.

Foods, Journal Year: 2025, Volume and Issue: 14(8), P. 1434 - 1434

Published: April 21, 2025

The seeds of Cichorium glandulosum Boiss. et Huet. (CS) are known for various effects. However, the research on establishment quality evaluation standards CS is currently limited. Therefore, this study employed Ultra Performance Liquid Chromatography–Tandem Mass Spectrometry (UPLC-MS/MS) to analyze components CS. Forty-nine compounds were identified through manual analysis and database comparison. then verified using HPLC standards. Additionally, 19 batches collected establish fingerprint chromatogram. Five major chemical selected subsequent analysis. MIR, combined with three variable selection algorithms preprocessing methods, was used build prediction models. For indexes Chlorogenic Acid, 1,4-Dicaffeoylquinic 1,5-Dicaffeoylquinic R2 values both training set test above 0.9, RPD all greater than 2.5, RER 10. This indicated that combination mid-infrared spectroscopy chemometrics had excellent model applicability performance these indexes. A system has been initially established, laying a foundation

Language: Английский

Citations

0
ND-FISH with New Oligo Probes for Chromosome Identification of Cichorium intybus Revealing Karyotypic Variation and Divergence of Asteraceae Species DOI Creative Commons

Mei‐Ling Chen,

Chengzhi Jiang,

Doudou Huang

et al.

Plants, Journal Year: 2024, Volume and Issue: 13(22), P. 3135 - 3135

Published: Nov. 7, 2024

Chicory (

Language: Английский

Citations

0
Isolation and PCR Validation of DNA from Chicory (<i>Cichorium intybus</i> L.) Leaves Using an Optimized CTAB Method to Propel Medicinal Insights DOI Open Access
Shadab Ahamad, M. P. S. Arya,

Gohar Taj

et al.

Journal of Diseases and Medicinal Plants, Journal Year: 2024, Volume and Issue: 10(4), P. 69 - 72

Published: Dec. 27, 2024

Isolating and purifying DNA from plants, particularly species like <i>Cichorium intybus </i>(chicory), poses significant challenges due to the presence of rigid cell walls high levels polyphenols polysaccharides. These compounds can severely hinder efficiency traditional extraction protocols, often resulting in poor-quality DNA. Conventional methods, such as Cetyl-trimethyl-ammonium bromide (CTAB) protocol, are found inadequate these biochemical barriers. In this study, we formulated an optimized isolation protocol for chicory that eliminates need liquid nitrogen phenol during processing. The refined approach resulted high-quality suitable downstream applications. effectiveness method was validated by polymerase chain reaction (PCR) amplification sucrose: sucrose 1-fructosyl transferase (<i>1-SST)</i> gene, a key gene involved biosynthesis inulin- compound with notable medicinal nutritional value. PCR yielded expected 2.01 kb product, confirming quality integrity extracted Overall, quantity were well-suited molecular analysis, demonstrating success our method. This provides valuable tool research on other plants similar challenges, facilitating more efficient genetic studies holding potential advancing biotechnological

Language: Английский

Citations

0
Cichorium intybus L., Asteraceae: Taxonomy, chemical composition and pharmacological activity DOI Open Access

Filip Balaž,

Ana Tomás,

Nevena Grujić

et al.

Hrana i ishrana, Journal Year: 2024, Volume and Issue: 65(1), P. 1 - 9

Published: Jan. 1, 2024

Cichorium intybus L. (chicory), Asteraceae, is extensively recognized for its historical and modern uses in healthcare, agriculture, dietary practices. This study highlights the taxonomy, bioactive compounds, therapeutic properties of chicory. The species rich substances, such as inulin, phenolic acids (e.g., chlorogenic caffeic acids), sesquiterpene lactones, flavonoids quercetin luteolin). These phytochemicals are key to free radical scavenging, inflammation-modulating hepatoprotective action, microbial growth inhibition, anthelmintic blood sugar regulation. Inulin serves a prebiotic fiber, promoting gut health metabolic regulation, while exhibit potent antioxidant anticancer activities. Sesquiterpene lactones contribute anti-inflammatory antimicrobial effects, whereas enhance plant's potential by modulating biological pathways. Chicory's pharmacological applications extend liver protection, glucose metabolism immune modulation, underscoring managing chronic diseases. Despite extensive profile, further clinical studies necessary confirm efficacy, establish optimal dosages, explore long-term safety. work supports integration chicory into functional foods pharmaceutical formulations, leveraging diverse benefits address global challenges.

Language: Английский

Citations

0