The role of vitamin D levels in the development and progression of kidney disease: The current state of the problem. A review DOI
И. Н. Захарова, А. Н. Цуцаева, Leonid Klimov

et al.

Pediatrics Consilium Medicum, Journal Year: 2025, Volume and Issue: 1(1), P. 44 - 50

Published: April 4, 2025

Progressive loss of kidney function is associated with significant morbidity and mortality an important global health concern, given the high prevalence chronic disease (CKD). Recently, there has been increased interest in finding new therapeutic strategies that may slow progression renal dysfunction. Numerous studies using various experimental models have proven treatment active metabolites vitamin D can a renoprotective effect, preventing fibrosis, apoptosis, inflammation. In addition, deficiency insufficiency are common conditions CKD patients pre-dialysis stages. It established serum level directly proportional to function. Recent clinical shown reducing proteinuria receiving goes beyond classical role maintaining bone mineral metabolism. Therefore, analogs potential become components achieve better outcomes advanced those on hemodialysis. Current guidelines recommend only moderate secondary hyperparathyroidism deficiency. This review presents results numerous demonstrating among diseases, effect rate progression, as well use infectious non-infectious diseases.

Language: Английский

A Comprehensive Review on the Beneficial Roles of Vitamin D in Skin Health as a Bio-Functional Ingredient in Nutricosmetic, Cosmeceutical, and Cosmetic Applications DOI Creative Commons

Sofia Neonilli A. Papadopoulou,

Elena A. Anastasiou,

Theodora Adamantidi

et al.

Applied Sciences, Journal Year: 2025, Volume and Issue: 15(2), P. 796 - 796

Published: Jan. 15, 2025

Vitamin D, also called the “sunshine” vitamin, has gained great attention recently due to observed high percentage of worldwide population being deficient in this essential bioactive vitamin. Primarily, vitamin D was known for its important role bone health. Nevertheless, recent research shown importance brain, heart, muscles, immune system, and skin health, distinct bio-functionality almost every tissue human body. Therefore, deficiency been highly correlated with multiple diseases, including dermatologically associated ones. Moreover, different methodologies are applied synthesize while main sources plasma levels factors that can cause adverse modifications multiple. Further upon exhibited notable against such as psoriasis, atopic dermatitis, vitiligo, acne, rosacea. In article, a critical review most relevant significant information regarding relationship between health is thoroughly conducted, emphasis given potential uses benefits several cosmetic applications. Current status, limitations, future perspectives potent extensively discussed.

Language: Английский

Citations

2
The role of vitamin D levels in the development and progression of kidney disease: The current state of the problem. A review DOI
И. Н. Захарова, А. Н. Цуцаева, Leonid Klimov

et al.

Pediatrics Consilium Medicum, Journal Year: 2025, Volume and Issue: 1(1), P. 44 - 50

Published: April 4, 2025

Progressive loss of kidney function is associated with significant morbidity and mortality an important global health concern, given the high prevalence chronic disease (CKD). Recently, there has been increased interest in finding new therapeutic strategies that may slow progression renal dysfunction. Numerous studies using various experimental models have proven treatment active metabolites vitamin D can a renoprotective effect, preventing fibrosis, apoptosis, inflammation. In addition, deficiency insufficiency are common conditions CKD patients pre-dialysis stages. It established serum level directly proportional to function. Recent clinical shown reducing proteinuria receiving goes beyond classical role maintaining bone mineral metabolism. Therefore, analogs potential become components achieve better outcomes advanced those on hemodialysis. Current guidelines recommend only moderate secondary hyperparathyroidism deficiency. This review presents results numerous demonstrating among diseases, effect rate progression, as well use infectious non-infectious diseases.

Language: Английский

Citations

0