Immobilization of Nitrilase: Driving Efficiency and Sustainability in Pharmaceutical Synthesis DOI
Rahul Vikram Singh

ChemBioEng Reviews, Journal Year: 2025, Volume and Issue: unknown

Published: April 15, 2025

Abstract Enzyme immobilization has propelled the pharmaceutical sector forward by playing a critical role in chemical synthesis; therefore, biocatalyst reuse industries received significant attention due to its eco‐friendly nature and potential for streamlining future utilization. In particular, nitrilases have emerged as biocatalysts synthesizing intermediates active ingredients (APIs). created platform nitrilase that significantly improved thermal stability reusability, increasing commercial value industry. The current article provides comprehensive analysis of recent advances continuous flow systems, focusing on how this approach contributes efficiency sustainability exploitation advantages immobilization, such stability, ease isolation, along with biocatalysts, proven be an invaluable tool pursuit more environment‐friendly efficient synthesis.

Language: Английский

Eco-pedagogy in chemistry education: challenging market-driven policies DOI
Ahmed Ali Alhazmi,

Rasha Ahmed Almashhour

International Journal of Sustainability in Higher Education, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 29, 2025

Purpose This study aims to examine the impact of market-driven policies on adoption and integration green chemistry into higher education in Saudi Arabia, uncovering challenges opportunities faced by educators institutions promoting sustainable scientific education. Design/methodology/approach used a grounded theory methodology explore Arabian amid policies. In-depth interviews were conducted with 22 participants, data analyzed using systematic coding process. Findings The reveals that significantly influence prioritizing immediate economic returns over long-term sustainability goals. Key include securing funding aligning traditional curricula. Opportunities promote through curricular reform policy adaptation identified. Research limitations/implications is limited education, which may affect generalizability findings other contexts. Practical implications Insights suggest policymakers should re-evaluate prioritization short-term gains develop incentives integrate chemistry. Institutions are encouraged invest faculty development, adopt interdisciplinary approaches collaborate industry government. Social Integrating promotes environmental stewardship prepares future generations address challenges. can shape environmentally conscious societies fostering culture ethical responsibilities. Originality/value contributes discourse providing theoretical analysis dynamics between integration, offering insights for policymakers, researchers.

Language: Английский

Citations

0

A Photochemical Vapor Generation Method for the Determination of Hg and Pb in Imitation Jewelry by Inductively Coupled Plasma Optical Emission Spectrometry DOI Creative Commons
Fabrício Braga, Jefferson Santos de Gois

Chemosensors, Journal Year: 2025, Volume and Issue: 13(4), P. 144 - 144

Published: April 14, 2025

The monitoring of contaminants in imitation jewelry has become important nowadays due to the high amount products sold worldwide. Due complexity sample matrix (composed mainly metals concentration), analysis can be very challenging. One interesting alternative for this purpose is use photochemical vapor generation coupled inductively plasma optical emission spectrometry (PVG-ICP-OES) ability separating analytes from solution prior analysis; additionally, it considered an eco-friendly approach if compared other techniques. Thus, work presents development and application a PVG-ICP-OES system determination Hg Pb after dissolution hydrochloric acid. PVG was built with two UV lamps (254 nm), quartz capillary reactor, glass gas-liquid separator. Acetic acid concentration exposure time were optimized using central composite design, as well carrier gas flow rate radiofrequency (RF) power ICP-OES. optimum conditions achieved at 30% v/v acetic acid, 60 s reaction time, 0.035 L min−1 rate, 1310 W RF power. influence chemical modifiers studied, where found that presence may cause suppression analytical signal. accuracy method evaluated by recovery tests, which ranged 88 102%. detection limits 1 3 mg g−1, allowing jewelry.

Language: Английский

Citations

0

Immobilization of Nitrilase: Driving Efficiency and Sustainability in Pharmaceutical Synthesis DOI
Rahul Vikram Singh

ChemBioEng Reviews, Journal Year: 2025, Volume and Issue: unknown

Published: April 15, 2025

Abstract Enzyme immobilization has propelled the pharmaceutical sector forward by playing a critical role in chemical synthesis; therefore, biocatalyst reuse industries received significant attention due to its eco‐friendly nature and potential for streamlining future utilization. In particular, nitrilases have emerged as biocatalysts synthesizing intermediates active ingredients (APIs). created platform nitrilase that significantly improved thermal stability reusability, increasing commercial value industry. The current article provides comprehensive analysis of recent advances continuous flow systems, focusing on how this approach contributes efficiency sustainability exploitation advantages immobilization, such stability, ease isolation, along with biocatalysts, proven be an invaluable tool pursuit more environment‐friendly efficient synthesis.

Language: Английский

Citations

0