Factors influencing COVID-19 vaccination: a study performed in fall of 2021 among Romanian adults from general practitioners

Humanities and Social Sciences Communications, Journal Year: 2025, Volume and Issue: 12(1)

Published: March 1, 2025

Language: Английский

---

The Impact of Infectious Diseases on Clinical Characteristics and Immunological Correlations in Pediatric Henoch–Schönlein Purpura: A Five-Year Retrospective Study

Biomedicines, Journal Year: 2025, Volume and Issue: 13(1), P. 113 - 113

Published: Jan. 6, 2025

Background/Objectives: Immunoglobulin A (IgA) vasculitis (IgAV), classically known as Henoch-Schönlein purpura (HSP), is a type of nonthrombocytopenic small-vessel vasculitis. HSP the most frequent kind systemic in children, characterized by purpura, arthritis or arthralgia, gastrointestinal pain, and kidney dysfunction. The aim our research was to investigate observe clinical characteristics children diagnosed with explore correlation between infectious diseases HSP. Furthermore, this retrospective study considered other factors, such demographic (sex, area/environment, age), their effect on pediatric population Methods: To answer question, we conducted five-year hospital-based that included 144 hospitalized who were during hospitalization. Measurements immunological panels (IgA, IgM, IgG, IgE), C3, C4, C-reactive protein, fibrinogen, hematite sedimentation rate (VSH) determined using blood samples revealed there strong elements panel manifestations. Results: Additionally, elevated IgG normal IgA serum levels patients are strongly associated diseases. Conclusions: Notably, exhibited high post-treatment higher risk relapses.

Language: Английский

---

Connecting the Dots: How MicroRNAs Link Asthma and Atherosclerosis

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(8), P. 3570 - 3570

Published: April 10, 2025

Asthma and atherosclerosis are chronic conditions with distinct pathophysiologies, but overlapping inflammatory mechanisms that suggest a potential common regulatory framework. MicroRNAs (miRNAs), small non-coding RNA molecules modulate gene expression post-transcriptionally, could be key players in linking these disorders. This review outlines how miRNAs contribute to the complex interplay between asthma atherosclerosis, focusing on involved pathways, immune cell regulation vascular remodeling. We discuss specific miRNAs, such as miR-155, miR-21 miR-146a, which have been shown cytokine production T differentiation, impacting respiratory cardiovascular health. The found both emphasize their role biomarkers, also therapeutic targets. Understanding molecular connections may unlock novel approaches for innovative, integrated treatment strategies address significantly improve patient outcomes. Further research is needed explore mechanistic pathways validate translational of miRNA-based interventions preclinical clinical settings.

Language: Английский

---

Exploration of Food Attitudes and Management of Eating Behavior from a Psycho-Nutritional Perspective

Healthcare, Journal Year: 2024, Volume and Issue: 12(19), P. 1934 - 1934

Published: Sept. 27, 2024

Background/Objectives: This study investigates the relationship between food attitudes and management of eating behavior from a psycho-nutritional perspective, with focus on Health Belief Model (HBM). The objective was to explore how emotional cravings influence different aspects dietary attitudes, identify indirect pathways through which these affect toward dieting behaviors. Methods: Data were collected 659 participants using validated scales that assessed tendencies, bulimia preoccupation, culinary behaviors, expectations positive outcomes, cravings. Descriptive statistics, Pearson’s correlations, network analysis employed uncover significant associations among variables. A sequential mediation conducted SPSS PROCESS Macro 6 pathways. Results: revealed Emotional craving had negative effect tendencies (effect size: −0.523) preoccupation 0.1006). These results highlight complex interplay cravings, in shaping attitudes. Conclusions: findings emphasize dynamic their collective impact provides insights into potential intervention strategies aimed at improving habits by addressing effects behavior.

Language: Английский

---

Osteoporosis: a problem still faulty addressed by the Romanian healthcare system. Results of a questionnaire survey of people aged 40 years and over

Frontiers in Medicine, Journal Year: 2024, Volume and Issue: 11

Published: Oct. 23, 2024

Purpose We aimed to investigate the knowledge and awareness level of osteoporosis, its risk factors, possible causes underdiagnosis, as well preventive measures lifestyle behavior Romanian population. Patients methods A non-interventional, cross-sectional study was performed, consisting an in-person survey, in 10 pharmacies located both urban rural settings Romania. The survey distributed patients ≥40 years old. Results Of 189 respondents, 78.8% were women, majority age group being 60–69 (31.7%) 50–59 (30.7%) old coming from areas (69.3%). Although 75.1% participants declared knowing about having a moderate knowledge, women more aware pathology, 77.3% have never performed DXA test. Moreover, already diagnosed with osteoporosis did not show better disease than those without diagnosis. Nearly half respondents know that family history increases developing it 60% them thought symptoms may develop before fracture occurs. strategies tend be disregarded thus, underused. 42.9% reported do undergo treatment, although they are existence effective strategies. dataset used build participant compatibility network. network’s clustering revealed six relevant communities, which correlated questionnaire results but reflect patterns feature associations. Conclusion Preventive therapeutic education programs urgently needed population decrease disability high mortality risks improve quality life.

Language: Английский

---

Under-Prescription of Drugs in the Elderly Population of Western Romania: An Analysis Based on STOPP/START Version 2 Criteria

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(19), P. 5970 - 5970

Published: Oct. 8, 2024

: Numerous European countries, including Romania, are facing the concern of rapid ageing their populations. Moreover, Romania's life expectancy ranks among lowest in Union. In light this, it is imperative that assessment medication-related harm be given national priority order to secure and enhance pharmacotherapy medical act. this study, we sought describe evaluate under-prescribing practices Romanian elderly population.

Language: Английский

---