Research Square (Research Square),
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 5, 2024
Abstract
In
the
present
study,
Alphinia
officinarum
rhizome
extract
and
zinc
nitrate
hexahydrate
were
utilized
to
synthesize
eco-friendly
cost-effective
oxide
(ZnO)
nanoparticles
(NPs).
Nanoparticles
of
Zinc
have
attained
unique
research
interest
among
various
metal
oxides.
Morphological
characterizations
ZnO
NPs
analyzed
using
X-ray
diffraction
(XRD),
Fourier
transform
infrared
spectroscopy
(FTIR),
scanning
electron
microscope
(SEM)
used
characterize
NPs.
FTIR
spectrum
revealed
presence
functional
groups
in
XRD,
microscope,
analyses
confirmed
crystal
structure
average
size
The
antimicrobial
activities
tested
on
microorganisms,
that
is,
P.
aeruginosa
ATCC
25619,
MRSA
43300,
C.
albicans
10231.
Moreover,
antibiofilm
activity
was
performed
against
shown
effective
microorganisms.
results
elucidated
cost-effectively
produced
could
be
as
coating
materials
a
wide
range
industrial
applications,
such
pharmaceutical
industries
cosmetics.
RSC Advances,
Journal Year:
2024,
Volume and Issue:
14(29), P. 20992 - 21034
Published: Jan. 1, 2024
This
paper
presents
a
comprehensive
review
of
recent
advancements
in
utilizing
zinc
oxide
nanoparticles
(ZnO
NPs)
to
enhance
antimicrobial
and
UV
protective
properties
healthcare
solutions.
Intelligent Pharmacy,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Aug. 1, 2024
ZnO-NPs
is
an
inorganic
metal
oxide
that
meets
as
medicine,
a
preservative
in
packaging,
well
antibacterial
agent
without
risk.
The
qualities
of
are
influenced
by
their
size,
shape,
concentration,
and
length
contact
with
the
bacterial
cell.
There
many
uses
for
ZnO
including
food
technology,
agriculture,
cosmetology,
optoelectronics,
drug
transporters,
agents.
potential
mediated
plant
extracts
superior
against
fungal
infections
human
diseases.
Trifolium,
Justicia
adhathoda,
Physalis
alkekengi
L,
Cassia
auriculata,
Pretence
blossoms,
Aloe
barbadenis,
Pongamia
pinnata,
Limoniaacidissima,
Plectranthusamboinicus,
Sedum
alfredii
Hance,
Aspidoterys
cordata
have
all
been
discovered
excellent
sources
synthesis
NPs.
above-mentioned
requirements,
which
can
be
utilised
risk16.
It
provides
overview
numerous
approaches,
characterization
techniques,
biomedical
organically
generated
food,
pharmaceutical
textile
sectors.
has
produced
green
more
useful
pharmacological
biological
applications,
particularly
antimicrobials.
Pharmaceutics,
Journal Year:
2023,
Volume and Issue:
15(11), P. 2634 - 2634
Published: Nov. 16, 2023
In
recent
years,
biosynthesized
zinc
oxide
nanoparticles
(ZnONPs)
have
gained
tremendous
attention
because
of
their
safe
and
non-toxic
nature
distinctive
biomedical
applications.
A
diverse
range
microbes
(bacteria,
fungi
yeast)
various
parts
(leaf,
root,
fruit,
flower,
peel,
stem,
etc.)
plants
been
exploited
for
the
facile,
rapid,
cost-effective
synthesis
ZnONPs.
Plant
extracts,
microbial
biomass
or
culture
supernatant
contain
biomolecules
including
enzymes,
amino
acids,
proteins,
vitamins,
alkaloids,
flavonoids,
etc.,
which
serve
as
reducing,
capping
stabilizing
agents
during
biosynthesis
The
ZnONPs
are
generally
characterized
using
UV-VIS
spectroscopy,
TEM,
SEM,
EDX,
XRD,
FTIR,
etc.
Antibiotic
resistance
is
a
serious
problem
global
public
health.
Due
to
mutation,
shifting
environmental
circumstances
excessive
drug
use,
number
multidrug-resistant
pathogenic
continuously
rising.
To
solve
this
issue,
novel,
effective
antimicrobial
needed
urgently.
Biosynthesized
could
be
novel
powerful
characteristics.
It
proven
that
strong
activity
against
microorganisms
bacteria.
possible
mechanisms
generation
reactive
oxygen
species,
physical
interactions,
disruption
cell
walls
membranes,
damage
DNA,
enzyme
inactivation,
protein
denaturation,
ribosomal
destabilization
mitochondrial
dysfunction.
review,
characterization
reviewed
comprehensively.
Also,
applications
highlighted.
Mikrobiolohichnyi Zhurnal,
Journal Year:
2023,
Volume and Issue:
85(6), P. 95 - 104
Published: Dec. 21, 2023
Antimicrobial
resistance
is
one
of
the
most
significant
threats
to
public
health
worldwide.
As
opposed
using
traditional
antibiotics,
which
are
effective
against
diseases
that
multidrug-resistant,
it
vital
concentrate
on
innovative
antibacterial
compounds.
These
innate
bacterial
arsenals
under
term
«bacteriocins»
refer
low-molecularweight,
heat-stable,
membrane-active,
proteolytically
degradable,
and
pore-forming
cationic
peptides.
Due
their
ability
attack
bacteria,
viruses,
fungi,
biofilm,
bacteriocins
appear
be
promising,
currently
accessible
alternative
for
addressing
antimicrobial
(AMR)
problem
minimizing
negative
effects
antibiotics
host’s
microbiome.
Nano-compounds
have
shown
promise
in
a
variety
applications,
including
agents,
drug
delivery
systems,
food
packaging
elements,
functional
formulations,
many
more.
However,
there
certain
disadvantages
chemical
production
nanoparticles
(NPs),
such
as
toxicity
other
impacts.
dual
action
biological
sources
combined
with
metallic
NPs,
use
conjugated
or
green-synthesized
has
become
more
widespread
during
past
ten
years.
Recently,
bacteriocin
emerged
viable
remedy
agent
vitro
overcome
some
these
limitations.
Scientific Reports,
Journal Year:
2024,
Volume and Issue:
14(1)
Published: Aug. 24, 2024
Abstract
In
this
study,
Ziziphus
spina
christi
leaves
was
used
to
synthesize
a
trimetallic
CuO/Ag/ZnO
nanocomposite
by
simple
and
green
method.
Many
characterizations
e.g.
FTIR,
UV–vis
DRS,
SEM–EDX,
TEM,
XRD,
zeta-size
analysis,
DLS,
were
confirm
green-synthesized
nanocomposite.
The
green,
synthesized
exhibited
spherical
dot-like
structure,
with
an
average
particle
size
of
around
7.11
±
0.67
nm
zeta
potential
21.5
mV.
An
extremely
homogeneous
distribution
signals,
including
O
(79.25%),
Cu
(13.78%),
Zn
(4.42%),
Ag
(2.55%),
is
evident
on
the
surface
green-synthetic
nanocomposite,
according
EDX
data.
To
best
our
knowledge,
first
study
effectively
use
industrially
produced
as
potent
antimicrobial
agent
employing
different
statistically
experimental
designs.
highest
yield
synthetic
(1.65
mg/mL),
which
enhanced
1.85
5.7
times;
respectively,
using
Taguchi
approach
in
comparison
Plackett–Burman
strategy
basal
condition.
A
variety
assays
techniques
utilized
evaluate
capabilities
at
200
µg/mL
concentration
against
multidrug-resistant
human
pathogens.
After
36-h
period,
tested
reduced
planktonic
viable
counts
studied
bacteria,
Escherichia
coli
Staphylococcus
aureus
,
showed
percentage
biofilm
reduction
(98.06
0.93
97.47
0.65%;
respectively).
