A particle of concern: explored and proposed underlying mechanisms of microplastic-induced lung damage and pulmonary fibrosis
R. K. Gautam,
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Laltanpuia,
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Nishant Singh
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et al.
Inhalation Toxicology,
Journal Year:
2025,
Volume and Issue:
unknown, P. 1 - 17
Published: Feb. 11, 2025
In
the
past
decade,
microplastics
(MPs)
have
drawn
significant
attention
as
widespread
environmental
contaminants,
with
research
increasingly
highlighting
their
harmful
effects
on
respiratory
health
in
aquatic
and
terrestrial
organisms.
Findings
revealed
human
lung
tissues,
raising
concerns
about
potential
role
damaging
tissue
integrity
contributing
to
pulmonary
fibrosis-a
chronic
inflammatory
condition
characterized
by
scarring
of
epithelial
tissues
due
accumulated
extracellular
matrix,
triggered
factors
such
alcohol,
pathogens,
genetic
mutations,
pollutants.
this
review,
we
explore
both
well-studied
lesser-studied
mechanisms
signaling
pathways,
aiming
shed
light
how
might
act
mediators
that
activate
distinct,
often
overlooked
cascades.
This
review
searched
PubMed
Google
Scholar
using
keywords
like
"plastic,"
"microplastic,"
"lung
fibrosis,"
"pulmonary
system,"
"exposure
route,"
"signaling
pathways,"
combined
"OR"
"AND"
singular
plural
forms.
These
pathways
could
not
only
induce
damage
but
also
play
a
development
fibrosis.
be
targeted
reduce
microplastic-induced
fibrosis,
opening
new
avenues
for
future
treatments.
Language: Английский
Quantification of tire wear particles in road dust based on synthetic/natural rubber ratio using pyrolysis-gas chromatography–mass spectrometry across diverse tire types
Sohee Jeong,
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Hyeonjung Ryu,
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Hyeokjin Shin
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et al.
The Science of The Total Environment,
Journal Year:
2024,
Volume and Issue:
942, P. 173796 - 173796
Published: June 7, 2024
Language: Английский
Semi-quantitative computational analysis of plastic additives in a FLOPP-E and SLOPP-E database subset
Wesley Allen Williams,
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Shyam Aravamudhan
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Microplastics and Nanoplastics,
Journal Year:
2025,
Volume and Issue:
5(1)
Published: March 5, 2025
Language: Английский
From the highway to receiving water bodies: identification and simultaneous quantification of small microplastics (< 100 µm) in highway stormwater runoff
Beatrice Rosso,
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Luca Vezzaro,
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Barbara Bravo
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et al.
Environmental Science and Pollution Research,
Journal Year:
2024,
Volume and Issue:
31(52), P. 61845 - 61859
Published: Oct. 23, 2024
Language: Английский
Semi-quantitative Computational Analysis of Plastic Additives in a FLOPP-E and SLOPP-E Database Subset
Wesley Allen Williams,
No information about this author
Shyam Aravamudhan
No information about this author
Research Square (Research Square),
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 11, 2024
Abstract
Microplastic
(MPL)
abundance
in
the
environment
and
biosphere
is
a
grave
problem
that
confounded
by
many
aspects,
one
vital
aspect
being
characterization
of
their
heterogeneous
matrix.
Currently,
spectroscopy,
chromatography,
soxhelation
aid
this
matter.
However,
these
techniques
are
time
consuming
for
MPL
characterization,
which
can
include
large
number
particles.
Therefore,
we
propose
facile
“Additive
Analysis”
algorithm
provide
top
ten
matches
additives
an
MPL.
For
our
first
trial,
used
2
entries,
from
FLOPP-E
(C2.
Blue
Fiber)
SLOPP-E
(Polyester
12.
Red
Fiber),
as
continuation
previous
work.
second
extended
use
to
semi-randomly
selected
subset
samples
based
on
choosing
1
sample
each
color
polymer.
Both
trials’
reference
in-lab
digitization
Hummel
database
Fourier-transform
Infrared
(FTIR)
spectroscopy
open-source
Raman
Nava.
We
determined
“C2.
Fiber”
contains
amounts
metal-free
phthalocyanine,
potentially
indicating
presence
degradation
context
controls
(t
10,.05:
.4879,
p:
.6387).
“Polyester
Fiber,”
high
likelihood
significant
quinone
azo-family
colorants
sample,
negating
hypothesis
pyrrole
(W:
0,
.036364).
49/56
27/40
hits
were
generated
out
randomly
samples,
with
vast
majority
possessing
(matching
sample)
within
most
scrutinizing
tolerance
5
1/cm
(77.6%/74.07%),
respectively.
FTIR
portion,
3
IDs
tolerances
5,
10,
15
benzenesulfonohydrazide
(1st
2nd
Hit),
titanium
dioxide
(4th
barium
permanganate/barium
sulfate
(6th
Hit).
PR210
(azo
derivative
–
PB25
muscovite
(mineral
1st
Lastly,
distribution
appears
identify
organic
azo-derivative
(Raman)
dominantly.
Our
discussion
concludes
potential
toxicological
impacts
6
IDs.
Language: Английский