Endocrine-Disrupting Compounds in Urban Soils of Malaysia: Occurrence, Contamination, and Impacts on Health and the Environment DOI Creative Commons

Michael Lie,

Joseph Kasongo,

Elias Mtui

et al.

Tropical Aquatic and Soil Pollution, Journal Year: 2024, Volume and Issue: 4(2)

Published: Oct. 11, 2024

Endocrine-disrupting compounds (EDCs) have garnered increasing concern in recent years due to their association with severe health issues and significant environmental impacts. EDCs, which can interfere endogenous hormone systems, are diverse structure often characterized by low molecular mass halogen substitutions. Their presence the environment, originating from both natural synthetic sources, has been well-documented water bodies, but studies on occurrence soils remain limited. This review provides a comprehensive overview of occurrence, contamination, impacts EDCs urban Malaysia. The paper discusses primary sources including pharmaceuticals, pesticides, industrial chemicals, combustion byproducts, examines pathways through these enter soil. Health risks associated exposure as well ecological consequences, also explored. highlights current status contamination Malaysian soils, identifies gaps research, outlines challenges monitoring mitigating contaminants. Understanding dynamics soil is crucial for developing effective strategies protect human environment settings.

Language: Английский

Identification of Endocrine Disrupting Chemicals Targeting NTD-related Hub Genes During Pregnancy via In Silico Analysis DOI
Junjie U. Guo, Hao Yu,

Yujun Guo

et al.

Reproductive Toxicology, Journal Year: 2025, Volume and Issue: unknown, P. 108904 - 108904

Published: April 1, 2025

Language: Английский

Citations

0
Epigenetic Mechanisms of Endocrine-Disrupting Chemicals in Breast Cancer and Their Impact on Dietary Intake DOI Creative Commons
Desh Deepak Singh

Journal of Xenobiotics, Journal Year: 2024, Volume and Issue: 15(1), P. 1 - 1

Published: Dec. 24, 2024

Addressing the consequences of exposure to endocrine-disrupting chemicals (EDCs) demands thorough research and elucidation mechanism by which EDCs negatively impact women lead breast cancer (BC). Endocrine disruptors can affect major pathways through various means, including histone modifications, erroneous expression microRNA (miRNA), DNA methylation, epigenetic modifications. However, it is still uncertain if modifications triggered help predict negative outcomes. Consequently, important understand how different endocrine disrupters or signals interact with regulate signalling mechanisms. This study proposes that epigenome may be impacted several EDCs, such as cadmium, arsenic, lead, bisphenol A, phthalates, polychlorinated biphenyls parabens, organochlorine, dioxins. Further, this also examines on lifestyle variables. In research, essential consider potential impacts EDC comprehend function in tissues.

Language: Английский

Citations

0
Comprehensive Study on Endocrine Disruptor Removal from Wastewater Using Different Microalgae Species DOI Creative Commons

Naoki Enrique Solano García,

Rosalı́a Rodrı́guez, Gemma Vicente

et al.

Applied Sciences, Journal Year: 2024, Volume and Issue: 15(1), P. 132 - 132

Published: Dec. 27, 2024

The concentration of endocrine disruptor compounds (EDCs) in wastewater is increasing, posing significant risks to living organisms. This study concerns the simultaneous degradation a variety EDCs from wastewater, including methylparaben (MeP), propylparaben (PrP), butylparaben (BuP), benzophenone (BP), bisphenol A (BPA), and estrone (E), presence microalgae Scenedesmus sp. or Chlorella vulgaris. potential for abiotic removal these their underlying mechanisms were also studied. significantly enhanced parabens, achieving complete within 7 days, primarily through mechanism biodegradation. BPA was improved by microalgae, reaching 82% 90% days with C. vulgaris, respectively. BP predominantly abiotic, accomplishing 95% days. E mainly approximately 40% notable contribution biodegradation later stages, accounting 27% final total provides insights into EDC highlighting vulgaris remove mixture wastewater.

Language: Английский

Citations

0
Endocrine-Disrupting Compounds in Urban Soils of Malaysia: Occurrence, Contamination, and Impacts on Health and the Environment DOI Creative Commons

Michael Lie,

Joseph Kasongo,

Elias Mtui

et al.

Tropical Aquatic and Soil Pollution, Journal Year: 2024, Volume and Issue: 4(2)

Published: Oct. 11, 2024

Endocrine-disrupting compounds (EDCs) have garnered increasing concern in recent years due to their association with severe health issues and significant environmental impacts. EDCs, which can interfere endogenous hormone systems, are diverse structure often characterized by low molecular mass halogen substitutions. Their presence the environment, originating from both natural synthetic sources, has been well-documented water bodies, but studies on occurrence soils remain limited. This review provides a comprehensive overview of occurrence, contamination, impacts EDCs urban Malaysia. The paper discusses primary sources including pharmaceuticals, pesticides, industrial chemicals, combustion byproducts, examines pathways through these enter soil. Health risks associated exposure as well ecological consequences, also explored. highlights current status contamination Malaysian soils, identifies gaps research, outlines challenges monitoring mitigating contaminants. Understanding dynamics soil is crucial for developing effective strategies protect human environment settings.

Language: Английский

Citations

0