Neurotoxicology of Metals DOI

Freeman Lewis,

Somaiyeh Azmoun,

Daniel Shoieb

et al.

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Language: Английский

Accumulation and depuration of tire wear particles in zebrafish (Danio rerio) and toxic effects on gill, liver, and gut DOI
Yun Zhang, Tianyu Zhao, Yanan Zhang

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 951, P. 175625 - 175625

Published: Aug. 18, 2024

Language: Английский

Citations

7
Synergistic neurotoxicity of clothianidin and photoaged microplastics in zebrafish: implications for neuroendocrine disruption DOI

Ping Ding,

Yajing Han, Yanan Sun

et al.

Environmental Pollution, Journal Year: 2025, Volume and Issue: unknown, P. 125797 - 125797

Published: Feb. 1, 2025

Language: Английский

Citations

0
Unravelling the developmental toxicity of heavy metals using zebrafish as a model: a narrative review DOI
Soumen K. Manna, Sayeed Mohammed Firdous

BioMetals, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 22, 2025

Language: Английский

Citations

0
Triple combination exposure to MPs, Pb2+ and As3+ induces ferroptosis at environmentally relevant concentrations in early development of zebrafish DOI Creative Commons
Yue Cao, Xuebiao Yao, Yushan Zhu

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2025, Volume and Issue: 292, P. 117942 - 117942

Published: Feb. 26, 2025

Language: Английский

Citations

0
Evaluation of lead exposure effects on tissue accumulation, behavior, morphological and hemato-biochemical changes in common carp, Cyprinus carpio DOI Creative Commons
Syed Sikandar Habib,

Sawera Maqaddas,

Francesco Fazio

et al.

Journal of Trace Elements in Medicine and Biology, Journal Year: 2024, Volume and Issue: 86, P. 127523 - 127523

Published: Sept. 6, 2024

Language: Английский

Citations

3
Morpho-Anatomical Degeneration of Dopaminergic Neurons in Adult Zebrafish Brain after Exposure to Nickel DOI Creative Commons
Pietro Cacialli, Serena Ricci, Maurizio Lazzari

et al.

Fishes, Journal Year: 2024, Volume and Issue: 9(8), P. 319 - 319

Published: Aug. 12, 2024

Chronic exposure to heavy metals has been widely demonstrated induce pathological features in different tissues and, particular, the central nervous system. Specific neurons, including dopaminergic were observed be more susceptible toxic agents. Several previous studies performed on zebrafish (Danio rerio) models that nickel (one of most abundant metals) induces impairment memory and anxious-like behaviors. Nevertheless, this phenotypical evidence not associated with system damage, no reports showing effects neurons are available. In study, we aim analyze precise distribution variation adult after chronic (96 h) ions dissolved water at sub-lethal doses (0.4 mg L−1; 2 L−1 4 L−1). The treatment evaluated by measuring transcript protein levels tyrosine hydroxylase (TH), described as a neuron marker. As shown, expression th1 th2 genes was reduced entire brain treated nickel. Immunostaining analysis allowed us localize TH-expressing mainly posterior tuberculum, where they dose-dependent fashion. Consistently, TUNEL assay revealed significant increase apoptosis cells Our findings represent first effect

Language: Английский

Citations

0
Neurobehavioral and bioaccumulative toxicity in adult in‐vivo zebrafish model due to prolonged cadmium exposure in the presence of ketoprofen DOI Open Access

S Madesh,

Gokul Sudhakaran, Ramu Meenatchi

et al.

Journal of Biochemical and Molecular Toxicology, Journal Year: 2024, Volume and Issue: 38(11)

Published: Oct. 15, 2024

Increasing industrial activity causes the release of chemical compounds into aquatic habitats, including toxic heavy metals like cadmium and medications ketoprofen, posing considerable ecological concerns. Although previous studies have shown that ketoprofen individually cause cognitive impairment, there is a lack information on combined neurological effects two substances. We investigated consequences persistent exposure in presence adult zebrafish, providing an essential model for understanding cumulative impacts vertebrate organisms. Behavioral assessments, bioaccumulation rates, biochemical studies, histopathological exams were conducted over 42 days authentic environmental settings. The results our study show (10 µg/L) 100 at environmentally relevant concentrations had significant impact locomotor activity, social interactions, responses, indicating neurotoxicity co-exposure groups compared to single pollutant groups. Biochemical tests disturbances antioxidant defense systems, while histological examinations reveal structural changes zebrafish brain regions. Ketoprofen influences accumulation brain, underscoring importance conducting complete evaluations understand intricate interactions between pollutants. This improves complex medications, stressing need consider when assessing models.

Language: Английский

Citations

0
Triple Combination Exposure to Mps, Pb2+ and As3+ Induces Ferroptosis at Environmentally Relevant Concentrations in Early Development of Zebrafish DOI
Yue Cao,

Xiaole Zhao,

Xuebiao Yao

et al.

Published: Jan. 1, 2024

Language: Английский

Citations

0
Neurotoxicology of Metals DOI

Freeman Lewis,

Somaiyeh Azmoun,

Daniel Shoieb

et al.

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Language: Английский

Citations

0