Current Research in Biotechnology,
Journal Year:
2023,
Volume and Issue:
6, P. 100153 - 100153
Published: Jan. 1, 2023
Aflatoxins
(AFs)
are
naturally
occurring
mycotoxins
known
to
cause
a
considerable
threat
food
safety
and
affect
animal
health.
Rapid
reliable
analytical
methods
crucial
for
preventing
AF
contamination
in
the
global
supply
chain.
Many
conventional
detection
involve
complex
sample
preparation
steps,
lengthy
analysis
times,
multiple
handling
stages
which
lead
delays
obtaining
results,
addition
being
unaffordable
many
settings
with
resource
constraints.
Herein,
we
demonstrate
proof
of
concept
competitive
immunochromatographic
(IC)
strip
test
quantification
total
using
commercially
available
antibodies
low-cost
portable
CubeTM
analyzer.
We
conducted
preliminary
testing
our
point-of-need
(PON)
method
corn
samples
results
indicated
good
agreement
when
compared
gold
standard
HPLC
method.
Furthermore,
range
5–50
ppb
time
5
min,
makes
this
technology
suitable
rapid
meets
regulatory
requirements
samples.
also
real-time
data
sharing
capabilities
reader
proof-of-concept
centralized
cloud-based
databank,
that
developed
provide
timely
monitoring
different
parts
systems.
It
is
critical
be
easily
accessible
within
systems
dashboard
enable
early
warning,
data-driven
decision-making,
interventions,
improve
overall
coordination
between
various
stakeholders
system.
Foods,
Journal Year:
2024,
Volume and Issue:
13(11), P. 1746 - 1746
Published: June 2, 2024
Mycotoxins
are
well-known
secondary
metabolites
produced
by
several
fungi
that
grow
and
occur
in
different
crops
during
both
pre-harvest
post-harvest
conditions.
The
contamination
occurrence
of
mycotoxins
currently
represent
some
the
major
issues
entire
agri-food
system.
quantification
feeds
foodstuffs
is
extremely
difficult
because
low
concentration
ranges;
therefore,
sample
collection
preparation
essential
to
providing
accurate
detection
reliable
quantification.
Currently,
analytical
methods
available
for
feed
food
products,
liquid
chromatography
coupled
with
high-resolution
mass
spectrometry
(LC-HRMS)
represents
most
instrumental
approach.
In
particular,
fast
development
high-throughput
has
made
it
possible
screen
analyze,
same
run
high
accuracy,
multiple
mycotoxins,
such
as
those
regulated,
masked,
or
modified,
emerging
ones.
Therefore,
aim
this
review
provide
an
overview
state
art
occurrence,
health-related
concerns,
analyses,
discussing
need
perform
multi-screening
approaches
combined
omics
technologies
simultaneously
analyze
matrices.
This
approach
expected
more
comprehensive
information
about
profile
distribution
thus
enhancing
understanding
their
co-occurrence
impact
on
production
chain.
Foods,
Journal Year:
2024,
Volume and Issue:
13(12), P. 1845 - 1845
Published: June 12, 2024
In
the
realm
of
analysis,
lateral
flow
immunoassay
(LFIA)
is
frequently
utilized
due
to
its
capability
be
fast
and
immediate.
However,
biggest
challenge
LFIA
low
detection
sensitivity
tolerance
matrix
interference,
making
it
impossible
enable
accurate,
qualitative
analyses.
this
study,
we
developed
a
new
with
higher
affinity
sensitivity,
based
on
nanobody
(G8-DIG)
CuS
nanoflowers-Au
(CuS
NFs-Au),
for
aflatoxin
B
Biopolymer
gels
have
gained
tremendous
potential
for
therapeutic
applications
due
to
their
biocompatibility,
biodegradability,
and
ability
adsorb
bind
biological
fluids,
making
them
attractive
drug
delivery
therapy.
The
versatility
of
biopolymer
in
theranostic
backgrounds,
with
a
focus
on
integrating
imaging
features
facilitating
real-time
monitoring
delivery.
Different
methods
are
explored
agents
into
gels,
including
encapsulation,
surface
functionalization,
nanoparticle
encapsulation
layer-by-layer
assembly
techniques.
Integration
Agents
Real-Time
Monitoring
Drug
Delivery
We
summarize
the
synthesis
methods,
general
properties,
mechanisms
functionality,
demonstrating
broad
as
multimodal
systems
imaging-based
therapeutics.
These
techniques
not
only
enable
multiple
but
also
provide
signal
enhancement
targeted
facilitates,
increasing
diagnostic
accuracy
efficacy.
In
addition,
current
incorporating
discussed,
role
precise
monitoring.
Current Research in Biotechnology,
Journal Year:
2023,
Volume and Issue:
6, P. 100153 - 100153
Published: Jan. 1, 2023
Aflatoxins
(AFs)
are
naturally
occurring
mycotoxins
known
to
cause
a
considerable
threat
food
safety
and
affect
animal
health.
Rapid
reliable
analytical
methods
crucial
for
preventing
AF
contamination
in
the
global
supply
chain.
Many
conventional
detection
involve
complex
sample
preparation
steps,
lengthy
analysis
times,
multiple
handling
stages
which
lead
delays
obtaining
results,
addition
being
unaffordable
many
settings
with
resource
constraints.
Herein,
we
demonstrate
proof
of
concept
competitive
immunochromatographic
(IC)
strip
test
quantification
total
using
commercially
available
antibodies
low-cost
portable
CubeTM
analyzer.
We
conducted
preliminary
testing
our
point-of-need
(PON)
method
corn
samples
results
indicated
good
agreement
when
compared
gold
standard
HPLC
method.
Furthermore,
range
5–50
ppb
time
5
min,
makes
this
technology
suitable
rapid
meets
regulatory
requirements
samples.
also
real-time
data
sharing
capabilities
reader
proof-of-concept
centralized
cloud-based
databank,
that
developed
provide
timely
monitoring
different
parts
systems.
It
is
critical
be
easily
accessible
within
systems
dashboard
enable
early
warning,
data-driven
decision-making,
interventions,
improve
overall
coordination
between
various
stakeholders
system.
