The
impact
of
COVID-19’s
unexpected
outbreak
forced
the
scientific
world
to
thoroughly
seek
alternative
ways
treatment
in
order
overcome
hindrance
traditional
medicine
alleviating
symptoms
this
virus
and
possibly
be
an
option
for
a
potential
cure
near
future.
antibiotic
erythromycin,
which
was
introduced
1952,
has
been
reported
pose
effective
substitute
medication
various
ailments
such
as
skin,
respiratory,
bone,
female
reproductive
conditions,
cancer,
well
newly
added
aftermath.
Countries,
World
Health
Organization
health
industry
have
recruited
cooperated
with
numerous
universities
institutions,
so
tackle
demand
efficient
antibiotics,
USA
China
leading
effort.
Consequently,
catalytic
mechanism
erythromycin’s
synthesis
industrial
production
discussed
analyzed
further
gain
better
understanding
extrapolate
innovative
environmentally
friendly
methods
producing
antibiotic.
Therefore,
increase
improvement
erythromycin
should
globally
promoted,
deliver
more
results
against
infectious
diseases
COVID
–
19.
Journal of Environmental Management,
Journal Year:
2025,
Volume and Issue:
375, P. 124362 - 124362
Published: Feb. 1, 2025
The
Caloosahatchee
Estuary
in
southwest
Florida,
USA,
is
regularly
subject
to
the
introduction
of
toxic
Microcystis
aeruginosa
blooms,
often
originating
from
eutrophic
Lake
Okeechobee
via
C-43
Canal.
focus
this
study
was
determine
responses
one
these
introduced
blooms
progressively
elevated
salinity
levels
as
bloom
water
mass
moved
through
estuary.
In
upper
estuary,
salinities
were
freshwater,
and
surface
large
colonies
M.
observed,
along
with
peak
microcystin
toxin
concentrations
up
107
μg
L-1,
all
particulate
fraction.
mid-estuary,
increased
2-6,
again
259
however,
significant
extracellular
also
observed
(i.e.,
17.8
L-1),
suggesting
a
level
osmotic
stress
on
aeruginosa.
lower
ranged
6
25
very
few
viable
but
0.5
L-1)
present
throughout
column.
It
noteworthy
that
average
total
column
+
extracellular)
remained
constant
movement
during
its
transit
revealing
negligible
rate
degradation
ten-day
transit.
results
provide
insights
into
changes
distribution
gradient,
which
has
implications
for
management
risks
ecosystem
human
health,
how
may
be
affected
by
releases
three
control
structures
Discharge
rates
play
major
roles
Canal-Caloosahatchee
ecosystem.
potential
discharge
regulation
are
discussed
perspectives
allochthonous
autochthonous
origin.
Biosensors,
Journal Year:
2025,
Volume and Issue:
15(1), P. 41 - 41
Published: Jan. 13, 2025
In
recent
years,
environmental
and
food
safety
have
garnered
substantial
focus
due
to
their
intimate
connection
with
human
health.
Numerous
biosensors
been
developed
for
identifying
deleterious
compounds;
however,
these
reveal
certain
limitations.
Nanopore
sensors,
featuring
nano-scaled
pore
size,
demonstrated
outstanding
performance
in
terms
of
rapidity,
sensitivity,
selectivity
as
a
single-molecule
technique
surveillance.
this
review,
we
present
comprehensive
overview
nanopore
applications
two
fields.
To
elucidate
the
pioneering
roles
nanopores,
analytes
are
categorized
into
three
distinct
groups,
including
metal
ions,
synthetic
contaminants,
biotoxins.
Moreover,
variety
strategies
involved,
such
coalescence
ligand
probes,
implementation
chemical
reactions,
functionalization
etc.
These
scientific
studies
showcase
versatility
diversity
technique,
paving
way
further
developments
technology
safety.
Toxins,
Journal Year:
2024,
Volume and Issue:
16(4), P. 196 - 196
Published: April 19, 2024
Microcystins
(MCs),
natural
hepatotoxic
compounds
produced
by
cyanobacteria,
pose
significant
risks
to
water
quality,
ecosystem
stability,
and
the
well-being
of
animals,
plants,
humans
when
present
in
elevated
concentrations.
The
escalating
contamination
irrigation
with
MCs
presents
a
growing
threat
terrestrial
plants.
customary
practice
irrigating
crops
from
local
sources,
including
lakes
ponds
hosting
cyanobacterial
blooms,
serves
as
primary
conduit
for
transferring
these
toxins.
Due
their
high
chemical
stability
low
molecular
weight,
have
potential
accumulate
various
parts
thereby
increasing
health
hazards
consumers
agricultural
products,
which
serve
foundation
Earth's
food
chain.
can
bioaccumulate,
migrate,
potentially
biodegrade,
within
systems.
This
study
highlights
that
reservoirs
bioaccumulate
come
into
contact
Additionally,
it
investigates
mechanisms
organisms
employ
conjugation
microbial
processes
involved
MC
degradation.
To
gain
comprehensive
understanding
role
chain
elucidate
specific
associated
consuming
irrigated
contaminated
toxins,
further
research
is
necessary.
Environmental Technology,
Journal Year:
2025,
Volume and Issue:
unknown, P. 1 - 14
Published: March 8, 2025
The
escalating
of
water
pollution
associated
with
microcystins
(MCs)
and
antibiotic
resistance
genes
(ARGs)
poses
a
significant
environmental
challenge.
As
one
China's
most
crucial
systems,
the
Yangtze
River's
ecological
health
is
not
only
vital
for
regional
ecosystems
but
also
carries
global
significance.
While
concentration
MCs
detected
in
River
sediments
moderate,
impact
exogenous
on
ARGs
microbial
communities
within
these
remains
poorly
understood.
This
study
examines
18
sediment
samples
collected
from
six
regions
along
upper,
middle,
lower
reaches
River.
By
introducing
MCs,
we
analyzed
responses
sulfonamide
gene
(sul1),
tetracycline
(tetA),
integron
(intI1),
community
composition.
results
indicate
that
MC
inputs
significantly
affect
abundance
sediments,
sul1,
tetA,
intI1
exhibiting
general
increasing
trend.
However,
structure
was
substantially
affected
by
differences
exerting
greater
influence
composition
than
input.
Proteobacteria,
Bacteroidetes,
Acidobacteria,
Chloroflexi
were
dominant
phyla
sediments.
introduction
may
increase
risk
ARG
dissemination.
These
findings
enhance
our
understanding
how
dissemination
structures
ecosystem.
Processes,
Journal Year:
2024,
Volume and Issue:
12(7), P. 1533 - 1533
Published: July 21, 2024
The
impact
of
COVID-19’s
unexpected
outbreak
forced
the
scientific
community
to
seek
alternative
treatment
methods
in
order
overcome
hindrance
traditional
medicine
terms
alleviating
symptoms
this
virus.
Erythromycin,
which
was
introduced
1952,
is
an
antibiotic
that
reported
pose
as
effective
substitute
medication
for
various
ailments
such
skin,
respiratory,
bone,
and
female
reproductive
conditions,
cancer,
well
newly
added
COVID-19.
importance
both
erythromycin
molecule
catalyst
its
production,
namely
P450eryF
cytochrome
P450
family,
many
health-concerned
environmentally
related
applications,
has
led
several
countries,
World
Health
Organization
(WHO)
health
industry
recruit
cooperate
with
numerous
universities
institutions,
attempt
tackle
demand
efficient
antibiotics.
aim
study
discuss
further
analyze
overall
structure
catalytic
mechanism
erythromycin’s
synthesis
industrial
gain
a
better
comprehension
molecule’s
significance
value
pharmaceutical
field.
This
carried
out
through
citation
current
production
rates
per
country
latest
statistics
published
patents.
As
implied
manuscript,
increase
improvement
derivatives
should
be
globally
promoted
deliver
more
results
against
infectious
diseases,
