Synergistic Antimicrobial Mechanism of the Ultrashort Antimicrobial Peptide R₃W₄V with a Tadpole-like Conformation

Journal of Chemical Information and Modeling, Journal Year: 2024, Volume and Issue: 64(17), P. 6838 - 6849

Published: Aug. 26, 2024

Antimicrobial peptides (AMPs) are promising candidates in combating multidrug-resistant microorganisms because of their unique mode action. Among these peptides, ultrashort AMPs (USAMPs) possess sequences containing less than 10 amino acids and have some advantages over traditional AMPs. However, one the main limitations designing novel highly active USAMPs is that mechanism action at molecular level not well-known. In this article, we report antimicrobial USAMP verine (R

Language: Английский

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Effects of Pepa1 and Pepa2 on Human Red Blood Cell Membrane: A Molecular Dynamics Simulation Study

Published: Jan. 1, 2024

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Language: Английский

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Relevance of charged and polar amino acids for functionality of membrane toxin TisB

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Oct. 3, 2024

Language: Английский

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