Investigating the Relationship between TyG, TyG-BMI Index and Laboratory Indicators and COVID-19 Severity DOI Open Access
Cai Liang,

Huaiwu Jiang,

Pu Feng

et al.

Advances in Infectious Diseases, Journal Year: 2023, Volume and Issue: 13(04), P. 641 - 651

Published: Jan. 1, 2023

Objective: The objective of this study was to investigate the relationship between triglyceride-glucose (TyG) index, triglyceride-glucose-BMI (TyG-BMI) laboratory indices, and disease severity in patients with COVID-19. Methods: A retrospective analysis COVID-19 treated at a tertiary hospital Mianyang City, Sichuan Province, China, from 1 May 31 2023 performed. were divided into two groups: 66 cases moderate group 61 severe group. Additionally, 69 uninfected individuals medical examination center during same period selected as control Spearman rank correlation used determine indices severity. Multiple logistic regression performed identify factors affecting ROC curves constructed assess predictive value TyG TyG-BMI for Results: There significant differences smoking diabetes three groups (P < 0.05). levels ALT, AST, index higher compared groups, while ALB lower Correlation showed that TC, TG, HbA1c, positively correlated severity, negatively multivariate revealed ALB, risk COVID-19, smoking, demonstrated predicted an area under curve (AUC) 0.642, AUC 0.718 patients. Conclusion: Smoking, are valuable assessing having than index.

Language: Английский

The triglyceride-glucose index is a predictor of major adverse cardiovascular events in patients with coronary artery disease and psoriasis: a retrospective cohort study DOI Creative Commons

Bingqi Fu,

Yan Zeng, Man Wang

et al.

Diabetology & Metabolic Syndrome, Journal Year: 2024, Volume and Issue: 16(1)

Published: July 31, 2024

Abstract Background The association between the triglyceride-glucose (TyG) index and clinical outcomes in patients with both coronary artery disease (CAD) psoriasis is unclear. This study investigated TyG major adverse cardiovascular events (MACE) CAD psoriasis. Methods retrospective cohort included diagnosed who underwent angiography at Fuwai Hospital, Beijing, China, January 2017 May 2022. endpoint was occurrence of MACE or end follow-up time. Multivariate Cox proportional analysis restricted cubic splines (RCS) were used to determine MACE. Receiver operating characteristic (ROC) curves optimal threshold value for predicting Results enrolled 293 psoriasis, including 258 (88.1%) males a mean age 58.89 ± 9.61 years. Patients divided into four groups based on quartiles: Q1 ( N = 74), Q2 73), Q3 Q4 73). After adjusting potential confounders, independently associated MACE, as continuous variable (HR 1.53, 95% CI 1.03–2.28, P 0.035) categorical (Q1: reference; Q2: HR 1.85, 0.88–3.87, 0.105; Q3: 2.39, 1.14-5.00, 0.021; Q4: 2.19, 1.001–4.81, 0.0497; trend 0.039). RCS showed an linear (P-overall 0.027, P-non-linear 0.589). ROC curve that ≥ 8.73 (area under 0.60, 0.53–0.67). significantly 2.10, 1.32–3.34, 0.002). adjustment independent 2.00, 1.17–3.42, 0.011). Conclusions positive correlation might be Graphical

Language: Английский

Citations

2
The prognostic significance of insulin resistance in COVID-19: a review DOI
Esmaeil Mehraeen, Faeze Abbaspour, Maciej Banach

et al.

Journal of Diabetes & Metabolic Disorders, Journal Year: 2024, Volume and Issue: 23(1), P. 305 - 322

Published: Jan. 20, 2024

Language: Английский

Citations

1
Prognostic Value of Hyperglycemia and Insulin Resistance Among Patients with Confirmed COVID-19 Infections at Admission to the Alexandria Fever Hospital, Egypt DOI

Fathy Zakaria Alsewy,

Magdy Helmy Megallaa, Salma Alaa Eldin Imbaby

et al.

Metabolic Syndrome and Related Disorders, Journal Year: 2024, Volume and Issue: 22(7), P. 551 - 557

Published: April 29, 2024

The interaction between COVID-19 infection, hyperglycemia, and insulin resistance (IR) may lead to poor outcome.

Language: Английский

Citations

0
Hyperglycemia as a predictor of mortality in adult patients with COVID-19 hospitalized in a public hospital in Peru DOI Creative Commons
Juan B. Peña,

Sonia Chia,

Olga Flores

et al.

Endocrine and Metabolic Science, Journal Year: 2024, Volume and Issue: 16, P. 100185 - 100185

Published: June 3, 2024

To investigate the association between glycemic levels and mortality in patients without diabetes hospitalized for COVID-19 Perú. In a retrospective study conducted from April to June 2020 Cayetano Heredia hospital, 529 were admitted with positive SARS-CoV-2 laboratory result or computed tomography chest scan suggestive images of pneumonia. Patients classified into three groups according their first blood glucose measure. Group 1: level lower than 100 mg/dL; 2: mg/dL 126 mg/dL, 3: over mg/dL. Demographical characteristics, concomitant diseases, data, treatment received during hospitalization also described. Regression-adjusted models used analyze interest. The number who met inclusion criteria was 289. Mortality occurred 137 cases (47 %). 1, group 2 3 had 29/77 (38 %), 58/120 (48 50/92 (54 %) mortality/severe cases, respectively. After all available confounding factors adjusted, 73 % increased hazard compared ones (aHR: 1.73 [95%CI: 1.05–2.84]; p = 0.032). Hyperglycemia (≥ mg/dL) at baseline previous history is associated COVID-19. Routine testing should never miss measure glycemia as this allows timely management, thereby minimizing its negative impact on patients' outcomes. Clinical relevance Admission > non-diabetic significantly higher middle-income countries.

Language: Английский

Citations

0
COVID persistente como factor de riesgo de diabetes ¿Es la diabetes una nueva pandemia dentro de la pandemia de la enfermedad por el coronavirus de 2019 (COVID-19)? DOI Open Access

Francisco Cordero

Diabetes práctica, Journal Year: 2023, Volume and Issue: 14(3)

Published: Jan. 1, 2023

Aunque la emergencia planetaria por pandemia causada el virus SARS-CoV-2 parece haber llegado a su fin, persistencia de síntomas después infección, conocida como COVID persistente o Long COVID, es un problema médico y social alcance mundial. Alrededor del 43 % las personas infectadas este coronavirus experimentan largo plazo. Esto puede afectar cientos millones en todo mundo. Además, COVID-19 aumentar riesgo desarrollar enfermedades crónicas metabólicas, diabetes mellitus. Se ha observado que dañar células beta pancreáticas contribuir al desarrollo diabetes. La inflamación inducida también resistencia insulina función musculoesquelética organismo hígado. Existe una relación bidireccional entre diabetes, manera con mellitus tienen aumentado complicaciones COVID-19. Es esencial optimizar manejo metabólico los pacientes para que, caso ser infectados tengan mejor pronóstico sobre consecuencias ambas se pueda reducir así carga sistemas salud.

Citations

0
Investigating the Relationship between TyG, TyG-BMI Index and Laboratory Indicators and COVID-19 Severity DOI Open Access
Cai Liang,

Huaiwu Jiang,

Pu Feng

et al.

Advances in Infectious Diseases, Journal Year: 2023, Volume and Issue: 13(04), P. 641 - 651

Published: Jan. 1, 2023

Objective: The objective of this study was to investigate the relationship between triglyceride-glucose (TyG) index, triglyceride-glucose-BMI (TyG-BMI) laboratory indices, and disease severity in patients with COVID-19. Methods: A retrospective analysis COVID-19 treated at a tertiary hospital Mianyang City, Sichuan Province, China, from 1 May 31 2023 performed. were divided into two groups: 66 cases moderate group 61 severe group. Additionally, 69 uninfected individuals medical examination center during same period selected as control Spearman rank correlation used determine indices severity. Multiple logistic regression performed identify factors affecting ROC curves constructed assess predictive value TyG TyG-BMI for Results: There significant differences smoking diabetes three groups (P < 0.05). levels ALT, AST, index higher compared groups, while ALB lower Correlation showed that TC, TG, HbA1c, positively correlated severity, negatively multivariate revealed ALB, risk COVID-19, smoking, demonstrated predicted an area under curve (AUC) 0.642, AUC 0.718 patients. Conclusion: Smoking, are valuable assessing having than index.

Language: Английский

Citations

0