Hepatitis B Virus (HBV) Integration into the Host Genome and Molecular Mechanisms DOI Creative Commons
Sisi Chen, Xin Yan,

Hao Kang

et al.

IntechOpen eBooks, Journal Year: 2025, Volume and Issue: unknown

Published: March 6, 2025

Hepatitis B Virus (HBV)—infected host cells include more complex replication strategies and procedures. By delving into the strategy of HBV, scientists can better understand its life cycle infection mechanism, providing a theoretical basis for developing effective antiviral treatments. The HBV involves multiple steps, including genome reverse transcription, DNA synthesis, assembly viral particles, each which is potential drug target. integration has significant impact on promote long-term survival transmission virus in host. may interfere with normal function genes, lead to changes cell signaling pathways, even tumorigenesis. Through high-throughput sequencing technology bioinformatics analysis, were able pinpoint site genome, subsequent research. Studies have shown that specific sites are associated severity liver disease, offers new ideas early diagnosis treatment disease.

Language: Английский

Hepatitis B Virus (HBV) Integration into the Host Genome and Molecular Mechanisms DOI Creative Commons
Sisi Chen, Xin Yan,

Hao Kang

et al.

IntechOpen eBooks, Journal Year: 2025, Volume and Issue: unknown

Published: March 6, 2025

Hepatitis B Virus (HBV)—infected host cells include more complex replication strategies and procedures. By delving into the strategy of HBV, scientists can better understand its life cycle infection mechanism, providing a theoretical basis for developing effective antiviral treatments. The HBV involves multiple steps, including genome reverse transcription, DNA synthesis, assembly viral particles, each which is potential drug target. integration has significant impact on promote long-term survival transmission virus in host. may interfere with normal function genes, lead to changes cell signaling pathways, even tumorigenesis. Through high-throughput sequencing technology bioinformatics analysis, were able pinpoint site genome, subsequent research. Studies have shown that specific sites are associated severity liver disease, offers new ideas early diagnosis treatment disease.

Language: Английский

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