COVID-19, post-acute COVID-19 syndrome (PACS, “long COVID”) and post-COVID-19 vaccination syndrome (PCVS, “post-COVIDvac-syndrome”): Similarities and differences

Pathology - Research and Practice, Journal Year: 2023, Volume and Issue: 246, P. 154497 - 154497

Published: May 3, 2023

Worldwide there have been over 760 million confirmed coronavirus disease 2019 (COVID-19) cases, and 13 billion COVID-19 vaccine doses administered as of April 2023, according to the World Health Organization. An infection with severe acute respiratory syndrome 2 (SARS-CoV-2) can lead an disease, i.e. COVID-19, but also a post-acute (PACS, "long COVID"). Currently, side effects vaccines are increasingly being noted studied. Here, we summarise currently available indications discuss our conclusions that (i) these specific similarities differences PACS, (ii) new term should be used refer (post-COVID-19 vaccination syndrome, PCVS, colloquially "post-COVIDvac-syndrome"), (iii) is need distinguish between (ACVS) (PACVS) - in analogy PACS ("long Moreover, address mixed forms caused by natural SARS-CoV-2 vaccination. We explain why it important for medical diagnosis, care research use terms (PCVS, ACVS PACVS) order avoid confusion misinterpretation underlying causes enable optimal therapy. do not recommend "Post-Vac-Syndrome" imprecise. The article serves current problem "medical gaslighting" relation PCVS raising awareness among professionals supplying appropriate terminology disease.

Language: Английский

---

Opportunities Presented by COVID-19 for Healthcare Green Supply Chain Management and Sustainability Performance: The Moderating Effect of Social Media Usage

IEEE Transactions on Engineering Management, Journal Year: 2023, Volume and Issue: 71, P. 4441 - 4454

Published: Feb. 2, 2023

This research explores the opportunities presented by COVID-19 for green supply chains' environmental practices and ecological sustainability performances in healthcare sector. study investigates connections between uncertainty-fear of COVID-19, chain management (GSCM), three pillars a firm's performance (environmental, economic, social). Moreover, this examines moderating role social media usage (SMU) on effect healthcare-GSCM. When conducting empirical part, uses partial least squares structural equation modeling method based sample 483 managers. The findings prove that has beneficial impact Besides, SMU moderates relationship healthcare-GSCM, indicating importance gathering information sector during COVID-19. Likewise, when interacting with firms' performances, healthcare-GSCM positively impacts though it negligible economic performance. adds to "social cognitive theory" introducing concept Furthermore, "resource-based view "knowledge-based exploring SMU's outbreak.

Language: Английский

---

Vaccination with the Inactivated Vaccine (Sinopharm BBIBP-CorV) Ensures Protection against SARS-CoV-2 Related Disease

Vaccines, Journal Year: 2022, Volume and Issue: 10(6), P. 920 - 920

Published: June 9, 2022

Vaccination against coronavirus disease 2019 (COVID-19) has become an important public health solution. Developing a safe and effective vaccine COVID-19 is viable long-term solution to control the pandemic. As one of two inactivated severe acute respiratory syndrome virus 2 (SARS-CoV-2) vaccines developed in China that entered WHO emergency use list, Sinopharm BBIBP-CorV, aluminum-hydroxide-adjuvanted, whole-virus vaccine, been widely distributed, with more than 400 million doses administered 40 countries. The evidence safety, efficacy, effectiveness BBIBP-CorV gathered reviewed. We further comment on latest papers disclosed results between rAd26-rAd5, ChAdOx1.

Language: Английский

---

Efficacy of Linezolid in the management of pneumonic COVID-19 patients. Bioinformatics-based clinical study

The Journal of Infection in Developing Countries, Journal Year: 2024, Volume and Issue: 18(03), P. 326 - 331

Published: March 31, 2024

Introduction: At the beginning in July 2023, there has been a significant increase daily hospital admissions attributed to new variant of COVID-19. Aim this study is explore clinical benefits and outcomes using linezolid management pneumonic COVID-19 patients. Methodology: The included 230 patients with SARS-CoV-2 infection confirmed by RT-PCR. Group 1: 118 were managed Linazolid alongside steroids. 2: (control group) treated according Protocol for Egyptian outlines WHO guidelines (112 patients). Each patient group was categorized into 3 age groups: 20-40 years, 41-65 over 65 years. Patients carefully followed up until recovery or mortality. A docking analysis carried out investigate potential act as an Mpro inhibitor. Results: 1's average time 15.1 days contrast 18.7 2 (control). There no deaths reported. In silico investigations revealed that Linezolid able achieve binding mode comparable co-crystalized Conclusions: considered effective antiviral weapon against SARS-COV-2. It could be used plan individuals due SARS-COV-2 infection. We recommend it combat current wave caused Omicron EG-5 Variant.

Language: Английский

---

Perceptions, Knowledge, and Experiences of Using Face Masks among Egyptian Healthcare Workers during the COVID-19 Pandemic: A Cross-Sectional Study

Healthcare, Journal Year: 2023, Volume and Issue: 11(6), P. 838 - 838

Published: March 13, 2023

Using face masks appropriately is important for preventing the community spread of respiratory infections. A cross-sectional study was conducted to evaluate knowledge level and experience using between healthcare teams protect them limit COVID-19 infection. structured questionnaire distributed 228 members in July-December 2021. It divided into two sections consisted 29 questions a total possible score 0 29. The first section related perceptions about (13 items); second (16 items). average this 23.21/29 with respect their proper use techniques. team studied had satisfactory mask techniques, shed light on unsatisfactory practices. Following instructions very vital protecting person wearing infection during health care by blocking droplets produced speaking or coughing. Providing how pandemic critical increase awareness practice prevent from spreading.

Language: Английский

---

Assessment of the factors affecting the clinical outcomes of infection and safety of vaccines against SARS-CoV-2 among Egyptian patients

BMC Infectious Diseases, Journal Year: 2025, Volume and Issue: 25(1)

Published: March 19, 2025

Abstract Background Understanding the factors that influence clinical outcomes of COVID-19 and safety various vaccines is important to inform public health strategies, particularly in diverse communities. This study aimed assess affecting vaccination among Egyptian population. Methods In a retrospective study, we examined 1597 patients who tested positive for COVID-19. Among them, 1280 had received vaccination, while 317 not. We collected data from medical records, which included characteristics, comorbidities, disease severity, type adverse hematological effects postvaccination. calculated relative risk, odds ratio, 95% confidence intervals (CIs). Results 1,597 cases, 74.1% were mild, 24.8% moderate, 1.1% severe. Significant moderate/severe cases male sex (RR 0.78, CI 0.64–0.95), cardiovascular diseases 1.86, 1.32–2.64), respiratory 1.40, 1.08–1.82), diabetes mellitus 1.41, 1.07–1.86), previous infection 1.22, 1.02–1.46). Vaccination reduced severity with BBIBP-CorV (Sinopharm) showing significant protective effect (OR 0.62–0.98). Clinical presentations varied, 97.6% having an oxygen saturation ≥ 92%. Logistic regression indicated factors. Linear revealed increased hemoglobin leucocyte counts, whereas decreased platelet counts. Conclusion Vaccination, (Sinopharm), significantly reduces Egyptians, despite effects. trial number Not applicable.

Language: Английский

---

Spike protein-related proteinopathies: a focus on the neurological side of spikeopathies

Annals of Anatomy - Anatomischer Anzeiger, Journal Year: 2025, Volume and Issue: unknown, P. 152662 - 152662

Published: April 1, 2025

Language: Английский

---

Efficacy of COVID-19 vaccines

Microbial Pathogenesis, Journal Year: 2022, Volume and Issue: 171, P. 105729 - 105729

Published: Sept. 2, 2022

Language: Английский

---

Assessment of COVID-19 vaccination among healthcare workers in Iraq; adverse effects and hesitancy

PLoS ONE, Journal Year: 2022, Volume and Issue: 17(11), P. e0274526 - e0274526

Published: Nov. 18, 2022

Several messenger ribonucleic acid (mRNA) and inactivated COVID-19 vaccines are available to the global population as of 2022. The acceptance vaccine will play a key role in combating worldwide pandemic. Public confidence this is largely based on its safety effectiveness. This study was designed provide independent evidence adverse effects associated with among healthcare workers Iraq identify attitudes who rejected vaccination. We conducted cross-sectional collect data Pfizer, AstraZeneca, Sinopharm vaccines. Data were collected between October 2021 February A total 2,202 participants enrolled study: (89.97%) received injections (10.03%) hesitant receive Participants either Pfizer (62.9%), AstraZeneca (23.5%) or (13.6%). Most significantly less prevalent second dose than first dose. Notably, more females males. Following dose, experienced vaccine. Interestingly, prevalence infection two doses reduced compared those According vaccine-hesitated participants, insufficient knowledge (29.9%), expeditious development (27.6%) lack trust (27.1%) three major reasons for refusing results our indicated that these do not present significant problem should prevent successful control

Language: Английский

---

Vaccine Uptake and COVID-19 Frequency in Pregnant Syrian Immigrant Women

Vaccines, Journal Year: 2023, Volume and Issue: 11(2), P. 257 - 257

Published: Jan. 25, 2023

Immigrants have difficulties in the use of essential health services such as vaccinations. Vaccine uptake among pregnant immigrant women is very low. The aim study was to examine vaccination status who received an center (IHC) affiliated primary care institutions. research a retrospective-designed cross-sectional type study. sample consists Syrian from strengthened IHC District Health Directorate Istanbul between August 2020 and 2022. Age, trimesters, number pregnancies, high-risk pregnancy status, dates against influenza, COVID-19 tetanus, vaccine types were evaluated. statistical significance level determined p < 0.05. None had influenza vaccine. Of whose tetanus data evaluated, 29.7% at least two doses women, 19.4% vaccinated with minimum 4.2% infection during their pregnancy. fully COVID-19. Public interventions are needed improve coverage disadvantaged groups.

Language: Английский

---